Epilepsy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-08-23Clinical Trial Update: A Randomized Controlled Trial to Investigate Possible Drug-drug Interactions Between Clobazam and Cannabidiol [Phase 2]
Phase 2 randomized trial assessing potential drug-drug interactions between clobazam and cannabidiol in epilepsy; results posted after compl…
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CLINICAL_TRIALS trial_result · 2018-08-22Clinical Trial Update: A Dose-ranging Study With Brivaracetam in Patients From 16 to 65 Years With Refractory Partial Onset Seizures. [Phase 2]
Phase 2 dose-ranging study of brivaracetam in patients with refractory partial onset seizures completed; results posted.
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FDA approval · 2018-08-21FDA Approved: SABRIL — Supplemental Application (Lundbeck Pharmaceuticals LLC)
FDA approved a supplemental application for Sabril (vigabatrin) submitted by Lundbeck Pharmaceuticals LLC.
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FDA approval · 2018-08-21FDA Approved: SABRIL — Supplemental Application (Lundbeck Pharmaceuticals LLC)
The FDA approved a supplemental application for SABRIL (vigabatrin) by Lundbeck Pharmaceuticals LLC.
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CLINICAL_TRIALS trial_result · 2018-08-07Clinical Trial Update: Cognitive Effects of Treatment of Interictal Discharges [NA]
Clinical trial assessing cognitive effects of treatment of interictal discharges in epilepsy has completed and results posted.
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: An Open-Label, Safety and Tolerability Study of Chronic Intermittent Use of Diazepam Nasal Spray. [Phase 2]
This open-label Phase 2 study assessed the safety and tolerability of chronic intermittent diazepam nasal spray in epilepsy, and the trial w…
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults [Phase 3]
Phase 3 clinical trial evaluating CBD as adjunctive treatment for seizures in Lennox-Gastaut syndrome; trial completed with results posted i…
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: Cannabidiol Oral Solution as an Adjunctive Treatment for Treatment-resistant Seizure Disorder [Phase 3]
This clinical trial update reports the results of a Phase 3 study of cannabidiol oral solution as an adjunctive treatment for treatment-resi…
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FDA label_change · 2018-07-23FDA Approved: LAMICTAL — Supplemental Application (GlaxoSmithKline LLC)
FDA approved a supplemental application for Lamictal (lamotrigine) from GlaxoSmithKline, resulting in changes to the product labeling.
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FDA approval · 2018-07-23FDA Approved: LAMICTAL ODT — Supplemental Application (GlaxoSmithKline LLC)
FDA approved a supplemental application for Lamictal ODT (lamotrigine) submitted by GlaxoSmithKline LLC.
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CLINICAL_TRIALS trial_result · 2018-07-23Clinical Trial Update: Vagus Nerve Stimulation Titration Protocol to Improve Tolerance and Accelerate Adaptation
A completed clinical trial examining a titration protocol for the vagus nerve stimulator to improve tolerability and speed adaptation in epi…
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Antiepileptic Efficacy Study of GWP42003-P in Children and Young Adults With Dravet Syndrome (GWPCARE1) [Phase 3]
Phase 3 trial update on GWP42003-P in children and young adults with Dravet syndrome. Completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Evaluation of Stress Sensitivity and Hyperemotivity in Epilepsy Compared to and a Group of Healthy Volunteers [NA]
This clinical trial update describes a study evaluating stress sensitivity and hyperemotivity in people with epilepsy compared to healthy vo…
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CLINICAL_TRIALS trial_result · 2018-07-19Clinical Trial Update: A Dose-ranging Pharmacokinetics and Safety Study of GWP42003-P in Children With Dravet Syndrome (GWPCARE1) [Phase 2]
Phase 2 dose-ranging pharmacokinetics and safety study of GWP42003-P in children with Dravet syndrome completed; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: A Pilot Study of Creative Arts Interventions for Neurology Inpatients [NA]
Completed pilot trial assessing the feasibility and potential effects of creative arts interventions for neurology inpatients, including ind…
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: Eslicarbazepine Acetate Monotherapy Long Term Study [Phase 3]
A Phase 3 long-term monotherapy trial of eslicarbazepine acetate in epilepsy has completed, with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: Investigation of Human Epileptic Networks by fMRI [NA]
This clinical trial update reports that the investigation of human epileptic networks by functional MRI has completed.
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CLINICAL_TRIALS trial_result · 2018-07-10Clinical Trial Update: Detecting Generalized Tonic-Clonic Seizures With a Seizure Detection and Warning System in Epilepsy Patients
Completed clinical trial evaluating Brain Sentinel's Seizure Detection and Warning System for detecting generalized tonic-clonic seizures in…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: The Role of Serotonin in Seizures
A clinical trial exploring the role of serotonin in seizures conducted by NINDS has been terminated.
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Brain P-gp and Inflammation in People With Epilepsy
This clinical trial update reports the completion of a study evaluating brain P-glycoprotein and inflammation in people with partial epileps…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Brain Infusion of Muscimol to Treat Epilepsy [Phase 1]
A Phase 1 clinical trial evaluating brain infusion of muscimol for epilepsy was terminated.
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CLINICAL_TRIALS trial_result · 2018-07-02Clinical Trial Update: An Open-label Extension Study to Evaluate the Safety and Tolerability of Perampanel (E2007) Administered as an Adjunctive Therapy in Epilepsy Subjects [Phase 3]
An open-label extension study assessed the safety and tolerability of perampanel as an adjunctive therapy for epilepsy; the Phase 3 trial is…
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FDA approval · 2018-06-27FDA Approved: LAMICTAL — Supplemental Application (GlaxoSmithKline LLC)
The FDA approved a supplemental application for Lamictal (lamotrigine) submitted by GlaxoSmithKline LLC to update the product labeling.
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FDA approval · 2018-06-27FDA Approved: LAMICTAL ODT — Supplemental Application (GlaxoSmithKline LLC)
The FDA approved a supplemental application for LAMICTAL ODT (lamotrigine) from GlaxoSmithKline LLC. The approval updates the labeling for t…
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CLINICAL_TRIALS trial_result · 2018-06-20Clinical Trial Update: STEP: Enhanced Physical Activity in Children and Youth With Epilepsy [NA]
The STEP trial evaluating enhanced physical activity in children and youth with epilepsy has completed. The update does not include results.