Epilepsy
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: Intrinsic Optical Imaging Study to Map Neocortical Seizure in Human Epilepsy Patients
A clinical trial investigating intrinsic optical imaging to map neocortical seizures in human epilepsy patients has been terminated.
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: Compassionate Use Program With Brivaracetam for the Treatment of Patients With Epilepsy
An update on a compassionate-use program evaluating brivaracetam for patients with epilepsy.
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CLINICAL_TRIALS trial_result · 2025-06-18Clinical Trial Update: Neural Circulatory Control and SUDEP Risk.
This entry reports a Mayo Clinic clinical trial investigating neural circulatory control and the risk of sudden unexpected death in epilepsy…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: This Study Will Assess the Etiology, Potential Risk Factors, and Seizure Types in Patients Over 50 With Epileptic Seizure Disorder, Using Laboratory Tests, EEG, and Neuroimaging Findings.
This clinical trial seeks to identify the causes, risk factors, and seizure types in adults over 50 with epilepsy, employing laboratory test…
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FDA approval · 2025-06-17FDA Approved: ACETAZOLAMIDE — Original Application (Sagent Pharmaceuticals)
FDA approved Sagent Pharmaceuticals' Original Application for Acetazolamide, including Acetazolamide and Acetazolamide Sodium formulations.
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: ONO-2017 Study Japanese Patients With Primary Generalized Tonic Clonic Seizures. [Phase 3]
A Phase 3 clinical trial update for ONO-2017 in Japanese patients with primary generalized tonic-clonic seizures (epilepsy, generalized) sho…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: De-identified UNMH EEG Corpus Database Creation With Fully De-identified Clinical Information
This study aims to create a fully de-identified EEG corpus database linked to clinical information for epilepsy and status epilepticus and i…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Effect of Sulthiame on EEG in Childhood Epilepsy Syndromes
A clinical trial is evaluating the effect of sulthiame on EEG patterns in childhood epilepsy syndromes and is currently recruiting.
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FDA label_change · 2025-06-14FDA Approved: VALTOCO — Supplemental Application (Neurelis, Inc)
FDA approved a supplemental application for VALTOCO (diazepam) from Neurelis, Inc. The approval updates the product labeling.
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Study on Neurocognitive Plasticity in Patients With Focal and Drug-resistant Epilepsy [NA]
This clinical-trial update confirms the completion of a study evaluating neurocognitive plasticity in patients with focal, drug-resistant ep…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Prospective Regional Epilepsy Database
A prospective regional epilepsy database trial at Sahlgrenska University Hospital is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Deep Brain Stimulation vs. Vagus Nerve Stimulation for Epileptic Spasms [NA]
This clinical trial compares deep brain stimulation versus vagus nerve stimulation for epileptic spasms and is currently not recruiting.
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: TMS - Intracranial Electrodes [NA]
Update on an ongoing clinical trial evaluating transcranial magnetic stimulation with intracranial electrodes for epilepsy, currently enroll…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Characterization and Analysis of Evoked Cortical Responses in Participants With Medication-intractable Epilepsy [NA]
Clinical trial update on characterizing evoked cortical responses in participants with medication-intractable epilepsy. The study is current…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Predisposing Factors for Post-stroke Epilepsy
A clinical trial registered by Norwegian University of Science and Technology studying predisposing factors for post-stroke epilepsy, curren…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Functional Organization of the Superior Temporal Gyrus for Speech Perception [NA]
An update on an ongoing clinical trial studying the functional organization of the superior temporal gyrus for speech perception in people w…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Coronary and Cerebral Microvascular Dysfunction in Neurological Diseases
This entry provides an update on a clinical trial investigating coronary and cerebral microvascular dysfunction in stroke, epilepsy, and tra…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Spatiotemporal Dynamics of the Human Emotion Network [NA]
A UCSF-led clinical trial is investigating the spatiotemporal dynamics of the human emotion network and is currently enrolling by invitation…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Evaluation of Memory and Forgetting in Patients With Epilepsy [NA]
A completed clinical trial conducted by Hospices Civils de Lyon evaluated memory and forgetting in patients with epilepsy.
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Effects of Social Feedback on Intracranial EEG [NA]
A Dartmouth College-sponsored clinical trial is investigating how social feedback affects intracranial EEG signals in people with epilepsy a…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Safety of Cenobamate in Japanese Subjects With Partial Onset Seizures [Phase 2]
Phase 2 clinical trial update evaluating the safety of cenobamate in Japanese subjects with partial-onset seizures; the study (NCT06590896) …
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Lacosamide Intravenous Injection for Emergency Termination of Status Epilepticus
A clinical trial evaluating intravenous lacosamide for emergency termination of status epilepticus. The study is currently not recruiting.
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FDA approval · 2025-05-30FDA Approved: ACETAZOLAMIDE — Original Application (Aurobindo Pharma Limited)
FDA approved Aurobindo Pharma Limited's original application for a generic acetazolamide product.
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CLINICAL_TRIALS withdrawal · 2025-05-29Clinical Trial Update: Impact of Pharmaceutical Interviews on the Medication Adherence of Epileptic Patients [NA]
A clinical trial evaluating whether pharmaceutical interviews improve medication adherence in epilepsy patients has been terminated.
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EMA approval · 2025-05-28EMA Authorised: Lacosamide Accord (lacosamide) — Accord Healthcare S.L.U.
The European Medicines Agency authorised Lacosamide Accord for epilepsy. The product contains lacosamide and is marketed by Accord Healthcar…