Epilepsy
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Investigating the Role and Electrophysiological Characteristics of the Human Claustrum Based on SEEG [NA]
A completed clinical trial investigating the role and electrophysiology of the human claustrum in refractory epilepsy and consciousness usin…
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FDA approval · 2025-07-11FDA Approved: PERAMPANEL — Original Application (Novadoz Pharmaceuticals LLC)
FDA approved the original ANDA for PERAMPANEL from Novadoz Pharmaceuticals LLC, making a generic version of perampanel available. This suppo…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Pharmacogenetics-Based Study on Individualized Use of Sodium Valproate [Phase 4]
Phase 4 pharmacogenetics-based study investigating individualized use of sodium valproate in epilepsy; currently recruiting.
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Risk Factors and Outcomes in Patients Treated in Neurocritical Care
This clinical trial update summarizes risk factors and outcomes for patients treated in neurocritical care, covering conditions such as suba…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: RNS System NAUTILUS Study [Phase 3]
Update on the RNS System NAUTILUS Phase 3 trial. The study is currently active and not recruiting.
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Sleep and Rehearsal-Driven Memory in Epilepsy
This clinical trial is investigating sleep- and rehearsal-driven memory consolidation in epilepsy and is currently recruiting.
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FDA approval · 2025-07-07FDA Approved: PREGABALIN — Supplemental Application (Amneal Pharmaceuticals NY LLC)
The FDA approved a supplemental application for pregabalin filed by Amneal Pharmaceuticals NY LLC.
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients [Phase 1]
A Phase 1 dose-escalation trial to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of SIF001 in healthy volunteers and e…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: A Study to Investigate JNJ-40411813 in Combination With Levetiracetam or Brivaracetam in Epilepsy [Phase 2]
Phase 2 study evaluating JNJ-40411813 in combination with levetiracetam or brivaracetam for focal onset seizures in epilepsy; the trial has …
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Evaluation of the NaviFUS System in Drug Resistant Epilepsy [NA]
Clinical trials registry update showing the NaviFUS System is being evaluated for drug-resistant epilepsy, including temporal lobe epilepsy,…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Subcutaneous Intersectional Short Pulse Stimulation in Epileptic Patients [NA]
A clinical trial evaluating subcutaneous intersectional short pulse stimulation for epilepsy is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Cognitive Enhancement Intervention for Creating a Healthy L.I.F.E (Lifestyle Interventions for Epilepsy) [NA]
This entry reports a recruiting clinical trial evaluating a cognitive enhancement lifestyle intervention for epilepsy as part of the L.I.F.E…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Multimodal Study of the Human Brain Epilepsy Tissue [NA]
A multimodal study investigating human brain epilepsy tissue is currently recruiting under the sponsor Assistance Publique - Hôpitaux de Par…
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: Epidiolex® for Anxiety in Pediatric Epilepsy [Phase 4]
A Phase 4 trial evaluating Epidiolex for anxiety in pediatric epilepsy has completed; no results are provided in the snippet.
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FDA approval · 2025-07-01FDA Approved: PREGABALIN CAPSULES, CV — Supplemental Application (Cipla USA Inc.)
FDA approved a supplemental application for Pregabalin Capsules, CV from Cipla USA Inc., under ANDA to market this generic pregabalin capsul…
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FDA approval · 2025-07-01FDA Approved: CARBAMAZEPINE — Supplemental Application (Bionpharma Inc.,)
FDA approved a supplemental application for carbamazepine from Bionpharma Inc. This action confirms regulatory clearance for the product und…
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: Clinical Study Evaluating the Safety of Lactobacillus Probiotic in Children With Drug Resistant Epilepsy [Phase 2]
This clinical trial update reports the completion of a Phase 2 safety study evaluating a Lactobacillus probiotic in children with drug-resis…
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: HOBSCOTCH Phase III [NA]
Phase III trial update for HOBSCOTCH in epilepsy shows the study status is completed.
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Pre-operative Mapping of the Anterior Temporal Lobe Using Functional MRI Innovative Techniques in in Drug-resistant Epileptic Patients [NA]
This clinical trial update describes a study to map the anterior temporal lobe before surgery using innovative functional MRI techniques in …
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FDA approval · 2025-06-27FDA Approved: LEVETIRACETAM — Supplemental Application (Prasco Laboratories)
FDA approved a supplemental application from Prasco Laboratories for a generic version of levetiracetam.
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: A Study to Test the Safety and Tolerability of Brivaracetam in Children and Adolescents With Seizures [Phase 3]
A Phase 3 trial is evaluating the safety and tolerability of brivaracetam in children and adolescents with seizures; the study status is rec…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Investigating the Functional Characteristics During Wakefulness and Sleep Based on SEEG [NA]
A clinical trial at Xuanwu Hospital in Beijing is evaluating functional characteristics during wakefulness and sleep using SEEG in patients …
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FDA approval · 2025-06-26FDA Approved: LACOSAMIDE ORAL SOLUTION — Original Application (Ajenat Pharmaceuticals LLC)
The FDA approved lacosamide oral solution under an original generic application (ANDA 219699) from Ajenat Pharmaceuticals LLC.
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Electrophysiologic Studies of Cognition in Epilepsy Patients [NA]
The clinical trial examining electrophysiologic measures of cognition in drug-resistant epilepsy has completed and posted results.
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FDA approval · 2025-06-24FDA Approved: LACOSAMIDE — Supplemental Application (Glenmark Pharmaceuticals Inc. USA)
FDA approved a supplemental application for lacosamide from Glenmark Pharmaceuticals USA, enabling continued generic lacosamide under the AN…