Epidermolysis Bullosa
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Improve Adherence to Weak or Strong Opioid Analgesics at the Time of Care in Children With Hereditary Epidermolysis Bullosa
A completed clinical trial evaluating adherence to opioid analgesics in children with Epidermolysis bullosa.
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa [Phase 1]
Phase 1 pilot study update for ELK-003 Eye Drops to treat ocular manifestations of epidermolysis bullosa, currently active/not recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Epidermolysis Bullosa (Phase III, Cross-over) [Phase 3]
This clinical trial update describes a Phase III crossover study evaluating allogeneic ABCB5-positive dermal mesenchymal stromal cells for E…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Evaluation of the Efficacy of ROPIVACAINE in Children and Young Adults With Hereditary Epidermolysis Bullosa [NA]
This clinical trial update reports completion of a study evaluating the efficacy of ropivacaine in children and young adults with hereditary…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Reproductive Options in Inherited Skin Diseases
A clinical trial update indicates a study on reproductive options for inherited skin diseases is ongoing at Maastricht University Medical Ce…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: Characterization of the Microbiome in Colonized Dystrophic and Junctional Epidermolysis Bullosa Wounds Before and After Use of APR-TD011 ® Spray Solution [EARLY_Phase 1]
This early-phase (Phase 1) trial characterized the wound microbiome in dystrophic and junctional Epidermolysis Bullosa and examined changes …
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Pregabalin Treatment for RDEB Pain and Itch [Phase 3]
Phase 3 trial of pregabalin for pain and itch in recessive dystrophic epidermolysis bullosa has completed.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: MT2015-20: Biochemical Correction of Severe EB by Allo HSCT and Serial Donor MSCs [Phase 2]
Phase 2 trial results evaluating allogeneic hematopoietic stem cell transplantation and serial donor mesenchymal stromal cells for biochemic…
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Study of Cellutome System for Treatment of Individual Lesions in EB Pts [NA]
Completed clinical trial of the Cellutome System for treating individual lesions in Epidermolysis Bullosa; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2023-07-10Clinical Trial Update: Gene Transfer for Recessive Dystrophic Epidermolysis Bullosa [Phase 1, Phase 2]
Phase 1/2 clinical trial update for a gene transfer approach targeting recessive dystrophic epidermolysis bullosa has completed with results…
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: Phase III Efficacy and Safety Study of Oleogel-S10 in Epidermolysis Bullosa [Phase 3]
A Phase 3 clinical trial evaluating Oleogel-S10 for Epidermolysis Bullosa has completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: INM-755 (Cannabinol) Cream for Treatment of Epidermolysis Bullosa [Phase 2]
Phase 2 clinical trial of INM-755 (cannabinol) cream for epidermolysis bullosa has completed.
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CLINICAL_TRIALS trial_result · 2022-12-23Clinical Trial Update: A Neurokinin-1 Receptor Antagonist for the Treatment of Pruritus in Patients With Epidermolysis Bullosa [Phase 2]
Phase 2 trial investigating a neurokinin-1 receptor antagonist for pruritus in Epidermolysis Bullosa has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-12-05Clinical Trial Update: Phase 3, Open-label Clinical Trial of EB-101 for the Treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB) [Phase 3]
Phase 3 open-label trial of EB-101 for recessive dystrophic epidermolysis bullosa has completed.
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CLINICAL_TRIALS trial_result · 2022-05-03Clinical Trial Update: Topical Gentamicin Nonsense Suppression Therapy of EB [Phase 1, Phase 2]
A combined Phase 1/2 trial investigating topical gentamicin as a nonsense suppression therapy for Epidermolysis Bullosa has completed.
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CLINICAL_TRIALS trial_result · 2022-04-14Clinical Trial Update: Dose-ranging Study of Dentoxol® Mouthrinse for Managing Oral Symptoms in People With Epidermolysis Bullosa. [Phase 2]
A Phase 2 dose-ranging study evaluating Dentoxol Mouthrinse for oral symptoms in Epidermolysis Bullosa with oral ulcers; status currently un…
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CLINICAL_TRIALS trial_result · 2020-09-16Clinical Trial Update: Long Term Open-label Study Evaluating Safety of Diacerein 1% Ointment Topical Formulation in Subjects With Epidermolysis Bullosa Simplex [Phase 2]
Phase 2 long-term open-label study evaluating the safety of diacerein 1% ointment topical formulation in epidermolysis bullosa simplex.
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: To Evaluate the Pharmacokinetic of Diacerein and Rhein After Maximum Use in Patients With Epidermolysis Bullosa (EB) [Phase 1]
Phase 1 pharmacokinetic study evaluating diacerein and rhein after maximum use in patients with epidermolysis bullosa, completed with result…
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Study of Effectiveness and Safety of SD-101 in Participants With Epidermolysis Bullosa [Phase 2]
Phase 2 trial update on SD-101 for Epidermolysis Bullosa has completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-11-04Clinical Trial Update: Open-Label Extension Study to Evaluate the Safety of SD-101 Cream in Participants With Epidermolysis Bullosa [Phase 2]
Open-label extension study assessing safety of SD-101 cream in Epidermolysis Bullosa; terminated with posted results.
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CLINICAL_TRIALS trial_result · 2019-08-02Clinical Trial Update: Open Label Extension Study to Evaluate the Long-term Safety of Zorblisa (SD-101-6.0) in Patients With Epidermolysis Bullosa [Phase 3]
Open-label extension study assessing long-term safety of Zorblisa (SD-101-6.0) in Epidermolysis Bullosa; study terminated with results poste…
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CLINICAL_TRIALS trial_result · 2019-08-01Clinical Trial Update: Trial To Assess Efficacy Of A Chimeric Skin In Patients With Epidermolysys Bullosa [Phase 2]
Phase 2 trial update evaluating a chimeric skin product in patients with epidermolysis bullosa has completed.
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CLINICAL_TRIALS trial_result · 2019-07-02Clinical Trial Update: Neurokinin-1 Receptor Antagonist for the Treatment of Itch in EB Patients [Phase 2]
Phase 2 trial update for a neurokinin-1 receptor antagonist addressing itch in epidermolysis bullosa patients; results posted after completi…
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CLINICAL_TRIALS trial_result · 2018-10-16Clinical Trial Update: ESSENCE Study: Efficacy and Safety of SD-101 Cream in Participants With Epidermolysis Bullosa [Phase 3]
Phase 3 trial updates for SD-101 cream in Epidermolysis Bullosa have been completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-04-19Clinical Trial Update: The Efficacy of Trimethoprim in Wound Healing of Patients With Epidermolysis Bullosa [Phase 2]
A Phase 2 trial evaluating the efficacy of trimethoprim for wound healing in patients with Epidermolysis Bullosa has completed. The update s…