Epidermolysis Bullosa Simplex
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: An International, Multicenter, Randomized, Double-Blind, Parallel Group, Vehicle-Controlled, Phase 2/3 Study With Open-Label Extension Evaluating the Efficacy and Safety of Diacerein 1% Ointment for the Treatment of Generalized Epidermolysis Bullosa Simplex (EBS) [Phase 2, Phase 3]
An international, multicenter Phase 2/3 randomized, double-blind, parallel-group, vehicle-controlled study is evaluating the efficacy and sa…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: A Phase II, Placebo Controlled, Clinical Trial of Topical TolaSure Targeting Aggregated Mutant Keratin in Epidermolysis Bullosa Simplex [Phase 2]
Phase II placebo-controlled trial evaluating Topical TolaSure for aggregated mutant keratin in Epidermolysis Bullosa Simplex; currently recr…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: A 44-week Monocentric Open Study Assessing the Efficacy and Safety of Deucravacitinib in Adults With Inflammatory Genodermatoses [Phase 2]
Phase 2 monocentric trial evaluating the efficacy and safety of deucravacitinib in adults with inflammatory genodermatoses; currently recrui…
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CLINICAL_TRIALS withdrawal · 2025-06-05Clinical Trial Update: A Pilot Study to Explore the Role of Gut Flora in Epidermolysis Bullosa
A pilot study by ProgenaBiome evaluating the role of gut flora in Epidermolysis Bullosa has been withdrawn. The study covered Epidermolysis …
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: A 20-Week Study Assessing the Efficacy of Apremilast in Patients with EB Simplex Generalized [Phase 2]
A Phase 2 trial assessing apremilast for Epidermolysis Bullosa Simplex is currently recruiting at Centre Hospitalier Universitaire de Nice.
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CLINICAL_TRIALS trial_result · 2023-08-23Clinical Trial Update: Injections of Botulinic Toxin in Plantar Lesions of Localized Epidermolysis Bullosa Simplex [Phase 2, Phase 3]
Clinical trial update for botulinic toxin injections in plantar lesions of Epidermolysis Bullosa Simplex across Phase 2 and Phase 3.
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: INM-755 (Cannabinol) Cream for Treatment of Epidermolysis Bullosa [Phase 2]
Phase 2 clinical trial of INM-755 (cannabinol) cream for epidermolysis bullosa has completed.
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CLINICAL_TRIALS trial_result · 2020-09-16Clinical Trial Update: Long Term Open-label Study Evaluating Safety of Diacerein 1% Ointment Topical Formulation in Subjects With Epidermolysis Bullosa Simplex [Phase 2]
Phase 2 long-term open-label study evaluating the safety of diacerein 1% ointment topical formulation in epidermolysis bullosa simplex.
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: To Evaluate the Pharmacokinetic of Diacerein and Rhein After Maximum Use in Patients With Epidermolysis Bullosa (EB) [Phase 1]
Phase 1 pharmacokinetic study evaluating diacerein and rhein after maximum use in patients with epidermolysis bullosa, completed with result…
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CLINICAL_TRIALS trial_result · 2020-01-30Clinical Trial Update: Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study [Phase 2]
Phase 2 trial investigating topical sirolimus 2% for Epidermolysis Bullosa Simplex and related conditions has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-11-05Clinical Trial Update: Safety and Efficacy of Diacerein 1% Ointment for Subjects With Epidermolysis Bullosa Simplex (EBS) [Phase 2]
Phase 2 clinical trial of 1% diacerein ointment for epidermolysis bullosa simplex was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2017-12-06Clinical Trial Update: Effect of Broccoli Sprout Extract on Keratinocyte Differentiation in Normal Skin [Phase 1]
A Phase 1 trial funded by Johns Hopkins University evaluating whether broccoli sprout extract affects keratinocyte differentiation in normal…
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CLINICAL_TRIALS trial_result · 2017-10-24Clinical Trial Update: Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study [Phase 2]
Phase 2 clinical trial update evaluating topical sirolimus 2% for patients with epidermolysis bullosa simplex.
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CLINICAL_TRIALS research · 2015-06-12Clinical Trial Update: Diacerin for the Treatment of Epidermolysis Bullosa Simplex [Phase 2]
This document reports a Phase 2 clinical trial evaluating Diacerin for Epidermolysis Bullosa Simplex, with the current trial status listed a…
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CLINICAL_TRIALS trial_result · 2011-10-14Clinical Trial Update: Treatment of Dowling Maera Type of Epidermolysis Bullosa Simplex by Oral Erythromycin [Phase 3]
A Phase 3 clinical trial is evaluating oral erythromycin for the Dowling-Meara type Epidermolysis Bullosa Simplex.
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CLINICAL_TRIALS research · 2011-03-09Clinical Trial Update: Botulinumtoxin A Treatment in Epidermolysis Bullosa Simplex and Pachyonychia Congenita [Phase 2]
Phase 2 clinical trial update on Botulinumtoxin A for Epidermolysis Bullosa Simplex and Pachyonychia Congenita; sponsor is Uppsala Universit…