Ependymoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Phase I Study of APX005M in Pediatric Central Nervous System Tumors [Phase 1]
Phase I study of APX005M in pediatric central nervous system tumors; the trial is active but not recruiting and results have been posted. Sp…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 update on erdafitinib for FGFR-mutant relapsed or refractory pediatric cancers enrolled in the Pediatric MATCH trial; results were p…
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors [Phase 1]
The SJDAWN Phase 1 trial at St. Jude evaluated molecularly-driven doublet therapies for children and young adults with recurrent brain tumor…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Everolimus for Children With Recurrent or Progressive Ependymoma [Phase 2]
Everolimus was studied in a Phase 2 trial for children with recurrent or progressive ependymoma. The study is completed and results were pos…
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CLINICAL_TRIALS trial_result · 2024-04-24Clinical Trial Update: Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating palbociclib in relapsed or refractory pediatric tumors with activating alterations in cell cycle ge…
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CLINICAL_TRIALS trial_result · 2024-04-08Clinical Trial Update: Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children [Phase 1]
Phase 1b trial update for PVSRIPO in recurrent malignant glioma in children has completed enrollment and results posted.
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CLINICAL_TRIALS trial_result · 2024-04-05Clinical Trial Update: Molecular-Guided Therapy for Childhood Cancer [NA]
A completed clinical trial evaluating molecular-guided therapy for several childhood cancers, with results posted in April 2024.
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
This Phase 2 Pediatric MATCH trial evaluated vemurafenib in children with BRAF V600-mutant relapsed or refractory advanced solid tumors, non…
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CLINICAL_TRIALS trial_result · 2023-07-13Clinical Trial Update: Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors [Phase 2]
A Phase 2 clinical trial evaluated memantine for preventing cognitive late effects in pediatric patients undergoing cranial radiation therap…
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CLINICAL_TRIALS trial_result · 2023-05-16Clinical Trial Update: Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 Pediatric MATCH trial evaluating Ulixertinib for MAPK-pathway-mutant tumors in children, including advanced solid tumors, Non-Hodgki…
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CLINICAL_TRIALS trial_result · 2023-03-24Clinical Trial Update: A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer [Phase 1, Phase 2]
A phase 1/2 trial evaluating bempegaldesleukin (BEMPEG) in combination with nivolumab in pediatric and young adult patients with recurrent o…
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CLINICAL_TRIALS trial_result · 2023-03-02Clinical Trial Update: Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma [Phase 3]
A Phase 3 trial comparing maintenance chemotherapy versus observation after induction chemotherapy and radiation for newly diagnosed ependym…
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CLINICAL_TRIALS trial_result · 2021-12-28Clinical Trial Update: Carboplatin and Bevacizumab for Recurrent Ependymoma [Phase 2]
Phase 2 trial of carboplatin plus bevacizumab for recurrent ependymoma has completed, and results have been posted. The study evaluated effi…
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CLINICAL_TRIALS trial_result · 2021-11-30Clinical Trial Update: Marizomib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial, and Spinal Cord Ependymoma [Phase 2]
Phase 2 trial of marizomib for recurrent ependymoma in various locations was terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2020-12-10Clinical Trial Update: Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas [Phase 1, Phase 2]
Clinical trial update on proton beam radiation therapy for various adult brain tumors, spanning Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2020-08-26Clinical Trial Update: Bevacizumab and Lapatinib in Children With Recurrent or Refractory Ependymoma [Phase 2]
A Phase 2 trial evaluating bevacizumab and lapatinib in children with recurrent or refractory ependymoma has been completed with results pos…
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CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma [Phase 2]
Phase 2 trial update on risk-adapted therapy for young children with embryonal brain tumors, choroid plexus carcinoma, high-grade glioma, or…
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children [Phase 2, Phase 3]
This document is an update on a Phase 2/Phase 3 therapy optimization trial for relapsed or refractory pediatric brain tumors, which has comp…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Yoga Therapy in Treating Patients With Malignant Brain Tumors [NA]
This entry notes a terminated clinical trial at Wake Forest evaluating yoga therapy for adults with malignant brain tumors.
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor [Phase 1]
Phase 1 trial evaluating autologous dendritic cells loaded with brain tumor stem cells for progressive malignant brain tumors has completed.
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CLINICAL_TRIALS trial_result · 2017-03-01Clinical Trial Update: Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma [Phase 2]
Phase 2 trial evaluating observation or radiation therapy and/or chemotherapy and a second surgery in children after initial surgery for epe…
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CLINICAL_TRIALS trial_result · 2017-02-17Clinical Trial Update: Antineoplaston Therapy in Treating Patients With Ependymoma [Phase 2]
Phase 2 trial update on antineoplaston therapy for ependymoma; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2016-03-07Clinical Trial Update: AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors [Phase 1]
Phase 1 study of AZD2171 (cediranib) in children with recurrent, progressive, or refractory primary central nervous system tumors has comple…
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CLINICAL_TRIALS trial_result · 2016-02-02Clinical Trial Update: Phase I Study of 5-Fluorouracil in Children and Young Adults With Recurrent Ependymoma [Phase 1]
This clinical trial update reports the completion of a Phase I study evaluating 5-fluorouracil in children and young adults with recurrent e…
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CLINICAL_TRIALS trial_result · 2016-01-11Clinical Trial Update: Single-agent Erlotinib in Patients Previously Treated With Oral Etoposide in Protocol OSI-774-205 [Phase 2]
This is a Phase 2 trial update for single-agent erlotinib in ependymoma patients previously treated with oral etoposide (OSI-774-205); the s…