Eosinophilic Asthma
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CLINICAL_TRIALS trial_result · 2026-07-13Clinical Trial Results: Severe Asthma, MepolizumaB and Affect: SAMBA Study
Clinical trial results for SAMBA study evaluating Mepolizumab in severe eosinophilic asthma with psychological distress were completed and r…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Mepolizumab and Physical Activity in Severe Asthma
This document reports an update on a clinical trial evaluating mepolizumab with physical activity in severe asthma; the study is currently a…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: STEP: Phase IIIb Study of Benralizumab to Step-down Maintenance Therapy in Patients With Severe Eosinophilic Asthma [Phase 3]
Phase IIIb trial update for benralizumab as step-down maintenance therapy in severe eosinophilic asthma; the study is currently active but n…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma [Phase 2]
This entry describes a Phase 2 clinical trial evaluating KT-621 taken orally in adults with moderate-to-severe eosinophilic asthma; recruitm…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Mepolizumab Effectiveness in Patients With Chronic Rhinosinusitis, Nasal Polyps and Comorbid Severe Eosinophilic Asthma
A clinical trial update assessing the effectiveness of mepolizumab for patients with chronic rhinosinusitis with nasal polyps and comorbid s…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Real World Study to Capture Clinical and Patient Centered Outcomes in Adults With Severe Eosinophilic Asthma Treated With Benralizumab.
Real-world study results in adults with severe eosinophilic asthma treated with benralizumab (Fasenra) has been completed, focusing on clini…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Real-life Observational Study in Severe Eosinophilic Asthma Adult Participant Treated With Benralizumab in Italy
A real-world observational study in adults with severe eosinophilic asthma in Italy is evaluating outcomes for patients treated with benrali…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment [Phase 3]
Phase 3 trial evaluating benralizumab 30 mg SC as add-on therapy in uncontrolled eosinophilic asthma patients on medium-dose ICS-LABA, compa…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Changes in Gene Transcription and Immunophenotypes Following Mepolizumab Treatment for Asthma
This Mayo Clinic-sponsored clinical trial in eosinophilic asthma assessed mepolizumab and reports changes in gene transcription and immunoph…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Patient-Reported OUTcomes of Benralizumab in Real-World Use in Severe EosiNophilic Asthma Patients
This completed clinical trial update reports patient-reported outcomes for benralizumab used in real-world treatment of severe eosinophilic …
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Efficacy of Mepolizumab in Polish Patients With Severe Eosinophilic Asthma
A clinical trial update reports the efficacy of mepolizumab in Polish patients with severe eosinophilic asthma, with results posted on Clini…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Beyond EOsinophils: proteoMICS to Identify Potential Biomarker of Organ Damage and Response to MEPOLIZUMAB in EGPA [Phase 4]
A Phase 4 clinical trial update describes using proteoMICS to identify biomarkers of organ damage and response to mepolizumab in eosinophili…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: A Study to Evaluate the Long-term Safety, Pharmacodynamics and Efficacy of SHR-1703 in Eosinophilic Asthma Patients [Phase 2]
A Phase 2 clinical trial to evaluate the long-term safety, pharmacodynamics, and efficacy of SHR-1703 in patients with eosinophilic asthma, …
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CLINICAL_TRIALS withdrawal · 2025-12-15Clinical Trial Update: A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma. [Phase 3]
A Phase 3 clinical trial evaluating dexpramipexole for severe eosinophilic asthma in adolescents and adults has been terminated.
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Phase III Long-Term Extension Study With Dexpramipexole [Phase 3]
Areteia Therapeutics reports termination of the Phase III long-term extension study of dexpramipexole for eosinophilic asthma. The trial sta…
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CLINICAL_TRIALS other · 2025-12-15Clinical Trial Update: A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3) [Phase 3]
A Phase 3 trial (EXHALE-3) evaluating dexpramipexole for severe eosinophilic asthma in adolescents and adults has been terminated.
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Treatment With Mepolizumab on Patients With Severe Refractory Eosinophilic Asthma
This clinical trial update notes that a study evaluating mepolizumab in patients with severe refractory eosinophilic asthma has been complet…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: A Multi-dose Study on the Safety and Efficacy of Self-administered Intranasal AD17002 Treatment for Eosinophilic Asthma [Phase 2]
A Phase 2 multi-dose study of a self-administered intranasal treatment (AD17002) for eosinophilic asthma is listed as not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: REverse LuNg Airway and Vascular RemOdeling in Asthma ReMission (ReNORM) [NA]
Clinical trial REverse Lung Airway and Vascular Remodeling in Asthma Remission (ReNORM) is not yet recruiting and is studying asthma with eo…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: AD17002 Treating Poorly Controlled, Moderate to Severe Eosinophilic Asthma [Phase 1, Phase 2]
Clinical trial AD17002 for poorly controlled, moderate-to-severe eosinophilic asthma has completed Phase 1 and Phase 2 studies.
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma [Phase 3]
Phase 3 clinical trial update for dexpramipexole in adolescents and adults with eosinophilic asthma; the study is listed as active but not r…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Evaluating the Effect of Benralizumab in Severe, Poorly-controlled Eosinophilic Asthma Using Inhaled Hyperpolarized 129-Xenon MRI [NA]
This entry describes a clinical trial evaluating benralizumab for severe eosinophilic asthma using inhaled hyperpolarized Xenon-129 MRI, wit…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Eosinophil Subpopulations in Eosinophilic-associated Diseases
A University of Florence trial update notes a study on eosinophil subpopulations in eosinophilic diseases. The study includes eosinophilic a…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: The Influence of Mepolizumab on Structural and Inflammatory Cells in Severe Eosinophilic Asthma
ClinicalTrials.gov update describes a study examining the effect of mepolizumab on structural and inflammatory cells in adults with severe e…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Identification of Autoantigens in EGPA and Severe Eosinophilic Asthma
A completed study from Queen Mary University of London investigates autoantigens in eosinophilic granulomatosis with polyangiitis (Churg-Str…