Endotoxemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study [NA]
This document provides an update on a randomized, open-label trial evaluating Polymyxin B hemoperfusion for endotoxemic septic shock; the st…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive Components [NA]
An Ohio State University trial is evaluating how whole wheat and its major bioactive components influence gut microbiota and related health …
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults With Metabolic Syndrome [NA]
A completed clinical trial investigated cardiometabolic benefits of potatoes mediated along the gut–vessel axis in adults with metabolic syn…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Dietary Green Tea Confection For Resolving Gut Permeability-Induced Metabolic Endotoxemia In Obese Adults [NA]
A completed clinical trial from Ohio State University evaluated a green tea confection to address gut permeability–associated metabolic endo…
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Determining the Fingerprint of Endotoxin Tolerance [NA]
This completed clinical trial conducted by Radboud University Medical Center investigates the fingerprint of endotoxin tolerance in endotoxe…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Rifaximin in Cirrhosis: Effects on Endotoxin and Haemostatic Indexes [Phase 4]
A Phase 4 trial of rifaximin in liver cirrhosis investigating endotoxin and haemostatic indexes was terminated.
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CLINICAL_TRIALS trial_result · 2019-12-19Clinical Trial Update: Defibrotide in the Human Endotoxemia Model --- an Exploratory Trial Investigating the Effects and the Mechanisms of Defibrotide [Phase 4]
Exploratory Phase 4 trial investigating defibrotide effects and mechanisms in a human endotoxemia model in healthy volunteers.
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CLINICAL_TRIALS trial_result · 2019-02-22Clinical Trial Update: A New Model of Acute Febrile Disease [NA]
The clinical trial has completed a study modeling an acute febrile disease, including endotoxemia and metabolic or immobilization conditions…
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic Shock [NA]
Clinical trial update on the safety and efficacy of Polymyxin B hemoperfusion for septic shock, with completed status and results posted.
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: Effects of Vasopressors on Immune Response [Phase 4]
A Phase 4 clinical trial assessing the effects of vasopressors on the immune response in endotoxemia has completed.
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CLINICAL_TRIALS trial_result · 2016-06-23Clinical Trial Update: PK/PD of EA-230 During Endotoxemia [Phase 1]
Phase 1 study evaluating the pharmacokinetics and pharmacodynamics of EA-230 during endotoxemia; the trial has completed.
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CLINICAL_TRIALS trial_result · 2015-12-15Clinical Trial Update: Ticagrelor in Human Endotoxemia Response to Human Endotoxemia [NA]
A clinical trial evaluating ticagrelor in humans with endotoxemia has completed.
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CLINICAL_TRIALS trial_result · 2015-08-14Clinical Trial Update: The Effects of Atazanavir-induced Hyperbilirubinemia During Human Endotoxemia [NA]
This completed trial investigates the effects of Atazanavir-induced hyperbilirubinemia during controlled human endotoxemia to assess safety …
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: The Role of Dietary Fat on Postprandial Endotoxemia in Healthy Adults [NA]
A completed clinical trial evaluating whether dietary fat affects postprandial endotoxemia in healthy adults. The study status is listed as …
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CLINICAL_TRIALS trial_result · 2015-05-20Clinical Trial Update: Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1α [Phase 1, Phase 2]
Completed Phase 1/2 trial update examining how oxygen status (hypoxia, normoxia, hyperoxia) influences endotoxemia-induced inflammation and …
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR II [Phase 3]
Phase 3 study evaluating the in vivo effects of C1-esterase inhibitor on the innate immune response during endotoxemia; the trial status is …
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CLINICAL_TRIALS trial_result · 2013-06-27Clinical Trial Update: The Effects of Immunostimulation With GM-CSF or IFN-y on Immunoparalysis Following Human Endotoxemia [NA]
This clinical trial evaluated whether immunostimulation with GM-CSF or interferon-gamma can counteract immunoparalysis after endotoxemia; th…
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CLINICAL_TRIALS trial_result · 2013-04-10Clinical Trial Update: Probiotic Sport Study [NA]
A completed clinical trial evaluating a probiotic therapy for oxidative stress, inflammation, and endotoxemia.
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CLINICAL_TRIALS trial_result · 2011-06-20Clinical Trial Update: Antiinflammatoric and Antioxidative Effect of Melatonin in Human Endotoxaemia [Phase 4]
Phase 4 trial assessing the anti-inflammatory and antioxidative effects of melatonin in humans with endotoxemia; the study status is complet…
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CLINICAL_TRIALS trial_result · 2011-04-22Clinical Trial Update: In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia [NA]
A completed human trial evaluating the in vivo effects of a C1-esterase inhibitor on the innate immune response during endotoxemia.
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CLINICAL_TRIALS trial_result · 2010-11-05Clinical Trial Update: Anti-inflammatory Effects of GTS-21 After LPS [NA]
A completed trial evaluated the anti-inflammatory effects of the alpha7 nicotinic receptor agonist GTS-21 after LPS exposure in endotoxemia …
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CLINICAL_TRIALS trial_result · 2010-11-05Clinical Trial Update: The Effects of Oral Dipyridamole Treatment on the Innate Immune Response During Human Endotoxemia [Phase 4]
Phase 4 clinical trial evaluating the effects of oral dipyridamole on the innate immune response in humans with endotoxemia; the study statu…
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CLINICAL_TRIALS trial_result · 2009-10-01Clinical Trial Update: A Possible Therapeutic Role for Adenosine During Inflammation [Phase 1]
A Phase 1 study evaluates adenosine as a potential therapy to modulate inflammation in endotoxemia; the trial has completed.
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CLINICAL_TRIALS trial_result · 2008-10-17Clinical Trial Update: Blockade of Vascular Potassium Channels During Human Endotoxemia [Phase 1]
A Phase 1 study evaluated blockade of vascular potassium channels in humans with endotoxemia, and the trial has completed.
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CLINICAL_TRIALS trial_result · 2008-05-21Clinical Trial Update: Study of Gene Activity in Fat and Muscle in Diabetics and Healthy Controls [NA]
A completed clinical trial update from Rigshospitalet studying gene activity in fat and muscle in people with Type 2 diabetes and healthy co…