Endometrial Hyperplasia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Weight Loss Intervention With Tirzepatide and Progestin Intrauterine Device to Treat Endometrial Hyperplasia and Grade 1 Endometrial Cancer [Phase 2]
Phase 2 clinical trial evaluating tirzepatide in combination with a progestin-releasing intrauterine device to treat endometrial hyperplasia…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Mirena for the Treatment of Nonatypical Endometrial Hyperplasia for 6 Months [Phase 3]
A Phase 3 clinical trial is evaluating Mirena for six months as a treatment for nonatypical endometrial hyperplasia; the study is currently …
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Progestins for the Treatment of Endometrial Cancer or Precancers of the Uterus Before Surgery, The Pro-Window Trial [Phase 2]
Phase 2 trial update on progestins for treating endometrial cancer or precancers before surgery; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Uterine Preservation Via Lifestyle Transformation [Phase 2]
A Phase 2 clinical trial evaluating lifestyle transformation aimed at preserving the uterus in individuals with endometrial hyperplasia or G…
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CLINICAL_TRIALS withdrawal · 2026-01-12Clinical Trial Update: Primary Prevention and Uterine Preservation in Premenopausal Women With Obesity and Endometrial Hyperplasia [Phase 2]
Phase 2 trial investigating primary prevention and uterine preservation in premenopausal women with obesity and endometrial hyperplasia has …
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Cervical Cytology DNA Methylation for Endometrial Lesion Screening and Follow-up
This entry describes a planned clinical trial evaluating cervical cytology DNA methylation as a screening and follow-up tool for endometrial…
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FDA approval · 2025-12-12FDA Approved: MEDROXYPROGESTERONE ACETATE — Supplemental Application (Prasco Laboratories)
The FDA approved a supplemental application for Medroxyprogesterone acetate from Prasco Laboratories, resulting in labeling changes associat…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Effect of Metformin on Endometrial Thickness in Postmenopausal Breast Cancer Patients Receiving Tamoxifen [NA]
A completed clinical trial investigated whether metformin influences endometrial thickness in postmenopausal breast cancer patients undergoi…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Topical Lidocaine vs. Traditional Management in Manual Vacuum Aspiration Pain Management. [NA]
This document reports the completed clinical trial comparing topical lidocaine with traditional pain management during manual vacuum aspirat…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: POPQ Associated With Total Laparoscopic Hysterectomy
A clinical trial investigating POPQ assessment with total laparoscopic hysterectomy is sponsored by the Medical University of Silesia and is…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Surgical and Obstetric Outcomes in Endometrial Adenocarcinoma and Atypical Endometrial Hyperplasia With Conservative Treatment
A clinical trial evaluating surgical and obstetric outcomes in endometrial adenocarcinoma and endometrial hyperplasia when treated with cons…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Cohort Study of Intrauterine Diseases
An ongoing cohort study of intrauterine diseases (endometrial cancer, endometrial hyperplasia, and endometrial polyps) is currently recruiti…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: Metformin for the Treatment of Endometrial Hyperplasia [EARLY_Phase 1]
An early-phase Phase 1 trial evaluated metformin for treating endometrial hyperplasia and has completed, including cases with and without at…
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Frequency of Endometrial Cancer Precursors Associated with Lynch Syndrome
This completed clinical trial investigated how frequently precursors to endometrial cancer occur in individuals with Lynch syndrome.
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: Pilot Study: Can Ultrasound Guided Biopsy be Used as an Alternative to Hysteroscopy? [NA]
A completed pilot study evaluated ultrasound-guided biopsy as an alternative to hysteroscopy for evaluating endometrial conditions; results …
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: High Flow Oxygen During Operative Hysteroscopy. [NA]
A completed clinical trial evaluating the use of high-flow oxygen during operative hysteroscopy to assess safety and respiratory outcomes.
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Virtual Reality's Role in See&Treat Hysteroscopy [NA]
A completed clinical trial from Federico II University evaluated the use of virtual reality-assisted see-and-treat hysteroscopy for endometr…
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CLINICAL_TRIALS research · 2024-07-15Clinical Trial Update: Pipelle® Under Ultrasound Guidance (PUG) to Investigate Post-menopausal Bleeding. [NA]
A clinical trial is investigating Pipelle under ultrasound guidance (PUG) to evaluate post-menopausal bleeding, and recruitment is currently…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Prospective Study for Endometrial Carcinoma and Hyperplasia in Childbearing-age Women [NA]
This ClinicalTrials.gov entry describes a prospective study evaluating endometrial cancer and endometrial hyperplasia in childbearing-age wo…
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CLINICAL_TRIALS withdrawal · 2023-07-05Clinical Trial Update: Levonorgestrel-Releasing Intrauterine System (LNG-IUS) in the Management of Atypical Endometrial Hyperplasia [Phase 3]
Phase 3 trial of levonorgestrel-releasing intrauterine system for endometrial hyperplasia was withdrawn.
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CLINICAL_TRIALS trial_result · 2022-08-08Clinical Trial Update: A Pilot Study on Fertility Conservative Treatment of Atypical Endometrial Hyperplasia in Singapore [Phase 2]
A Phase 2 pilot study assessing fertility-conserving treatment for atypical endometrial hyperplasia conducted in Singapore.
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FDA approval · 2021-10-07FDA Approved: CLIMARA PRO — Supplemental Application (Bayer HealthCare Pharmaceuticals Inc.)
The FDA approved a supplemental application for Climara Pro (estradiol and levonorgestrel) submitted by Bayer, potentially updating labeling…
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CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial Hyperplasia [Phase 2]
Phase 2 trial of megestrol in endometrial neoplasia or endometrial hyperplasia was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2019-05-01Clinical Trial Update: Vaginal Estrogens Comparative Trial on Pelvic Organ Prolapse Patients [Phase 4]
Phase 4 clinical trial update comparing vaginal estrogens in pelvic organ prolapse patients has completed.
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CLINICAL_TRIALS trial_result · 2019-04-05Clinical Trial Update: A Study Comparing Mirena and Systemic Progestin for Endometrial Hyperplasia [Phase 4]
Phase 4 trial comparing Mirena to systemic progestin for endometrial hyperplasia has completed.