Empyema
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Pleural Space Saline Irrigation in Addition to Standard Intrapleural Thrombolytic Therapy in Empyema/Complicated Parapneumonic Effusion [NA]
A Mayo Clinic-sponsored clinical trial is recruiting to evaluate pleural space saline irrigation in addition to standard intrapleural thromb…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: UNC Pleural Fluid Registry
UNC Pleural Fluid Registry trial is currently recruiting to collect pleural fluid data from patients with several conditions including lung …
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Once Daily Intrapleural Enzyme Therapy in Complicated Parapneumonic Effusion or Empyema [Phase 4]
Phase 4 clinical trial evaluating once-daily intrapleural enzyme therapy for complicated parapneumonic effusion or empyema; currently NOT_YE…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Effectiveness and Safety of Sodium Bicarbonate Pleural Lavage in the Treatment of Complex Pleural Effusion [NA]
A clinical trial is recruiting to test the effectiveness and safety of sodium bicarbonate lavage for complex pleural effusion and empyema.
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Comparative Study Between Outcome of ICT Drainage and VATS in Management of Second Stage Empyema [NA]
A clinical trial protocol comparing intercostal tube drainage (ICT) with video-assisted thoracoscopic surgery (VATS) for second-stage empyem…
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CLINICAL_TRIALS trial_result · 2022-11-22Clinical Trial Update: Management of Pleural Space Infections [Phase 4]
A Phase 4 clinical trial update on managing pleural space infections (empyema and parapneumonic effusion) has completed.
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CLINICAL_TRIALS trial_result · 2022-09-27Clinical Trial Update: Trial of Antiseptic Irrigation for Pleural Infection [Phase 2]
Phase 2 clinical trial update for an antiseptic irrigation approach in pleural infection (empyema/pleural empyema).
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CLINICAL_TRIALS trial_result · 2022-01-27Clinical Trial Update: Treatment of Complicated Parapneumonic Effusion With Fibrinolytic Therapy Versus VATs Decortication [NA]
Clinical trial comparing fibrinolytic therapy to video-assisted thoracoscopic surgery (VATs) decortication for complicated parapneumonic eff…
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CLINICAL_TRIALS trial_result · 2021-02-04Clinical Trial Update: Fibrinolysis Compared to Thoracoscopy for Pleural Infection [Phase 4]
Phase 4 trial comparing fibrinolysis to thoracoscopy for pleural infection/ empyema has completed with posted results.
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CLINICAL_TRIALS trial_result · 2017-01-18Clinical Trial Update: Efficacy and Safety of Prophylactic Use of an Antibiotic for Medical Thoracoscopy [Phase 4]
Phase 4 clinical trial update evaluating prophylactic antibiotic use during medical thoracoscopy for pleural conditions, focusing on efficac…
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CLINICAL_TRIALS withdrawal · 2016-01-28Clinical Trial Update: Empyema Treated With tPA & DNAse [Phase 3]
A Phase 3 trial evaluating empyema treatment with intrapleural tPA and DNase has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-06-01Clinical Trial Update: Clinical Trial Corticoids For Empyema And Pleural Effusion In Children [Phase 2]
A Phase 2 trial evaluating corticosteroids for parapneumonic pleural effusion and empyema in children has completed.
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CLINICAL_TRIALS trial_result · 2014-08-21Clinical Trial Update: KatGuide Method Versus Conventional Method at Insertion of Chest Tube [Phase 3]
A Phase 3 trial comparing the KatGuide method to conventional chest tube insertion has completed, evaluating outcomes in pneumothorax and re…
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CLINICAL_TRIALS trial_result · 2012-04-24Clinical Trial Update: Efficacy and Safety of Activase (Ateplase) vs Placebo in Complicated Pleural Effusions (CPE)/Empyemas [NA]
Clinical trial evaluating intrapleural Activase (alteplase) versus placebo in complicated pleural effusions and empyema completed with resul…
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CLINICAL_TRIALS trial_result · 2011-09-07Clinical Trial Update: Procoagulant Activity in Patients With Community Acquired Pneumonia, Pleural Effusion and Empyema
A completed clinical trial studied procoagulant activity in patients with community-acquired pneumonia, pleural effusion, and empyema, spons…
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CLINICAL_TRIALS trial_result · 2008-05-09Clinical Trial Update: Thoracoscopy Versus Fibrinolysis in Children With Empyema [Phase 2, Phase 3]
A completed phase 2/3 clinical trial comparing thoracoscopy to fibrinolysis for treating empyema in children.
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CLINICAL_TRIALS research · 2006-08-01Clinical Trial Update: Alteplase for Treatment of Empyema and Complicated Parapneumonic Effusion [NA]
Clinical trial update on using alteplase to treat empyema and complicated parapneumonic effusion; current trial status is unknown.