Dupuytren Contracture
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Post-contracture Release Radiation for Dupuytren's Disease
This clinical trial update indicates recruitment is ongoing for a study evaluating radiation therapy after contracture release in Dupuytren'…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Ultrasound Features of Dupuytren's Disease [NA]
A clinical trial sponsored by Universitaire Ziekenhuizen KU Leuven is studying ultrasound characteristics of Dupuytren's contracture and is …
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Micronerves in Dupuytren and the Impact of Its Dissection on Recurrence
A clinical trial update noting that a study evaluating Micronerves for Dupuytren's disease is currently recruiting and examining the impact …
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring [NA]
A Mayo Clinic-sponsored clinical trial is evaluating whether prophylactic limited palmar fasciectomy affects surgical outcomes and scarring …
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CLINICAL_TRIALS trial_result · 2025-11-14Clinical Trial Update: NAC-REPAIR for Post-surgical Pain [Phase 2]
A Phase 2 clinical trial update for NAC-REPAIR addressing post-surgical pain across multiple hand and foot conditions, with the study status…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test [NA]
A clinical trial update from the University of Texas at Austin outlines a study to understand patient preferences for a voluntary musculoske…
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: Nylon Versus Chromic Gut Sutures for Minor Hand Surgery [NA]
An UT Austin-sponsored clinical trial comparing nylon versus chromic gut sutures for various minor hand surgeries has completed. The study e…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Preoperative Serial Casting, Education, and Therapy for Dupuytren's Contracture [NA]
A Bournemouth University trial investigates preoperative serial casting, education, and therapy for Dupuytren's contracture, with the study …
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Fasciectomy vs Collagenase Injection in Recurrent Dupuytren Disease [Phase 4]
Phase 4 clinical trial update comparing fasciectomy versus collagenase injection for recurrent Dupuytren disease; the study is active but no…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Trial Comparing Treatment Strategies in Dupuytren's Contracture [Phase 4]
Phase 4 clinical trial update for Dupuytren Contracture comparing treatment strategies; the study is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-02-26Clinical Trial Update: Effectiveness of Splinting After Collagenase Injection [Phase 3]
A Phase 3 clinical trial evaluated the effectiveness of splinting after collagenase injections for Dupuytren's contracture. The study has co…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist Surgery [Phase 4]
Phase 4 trial evaluating the efficacy of liposomal bupivacaine for ultrasound-guided supraclavicular nerve blocks in hand and wrist surgery.
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture [NA]
A clinical trial evaluating ultrasound-guided needle knife for Dupuytren's contracture is currently recruiting.
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: Radiation Therapy for Dupuytren's Contracture Following Non-Surgical Release [NA]
An ongoing clinical trial is evaluating radiation therapy after non-surgical release for Dupuytren's contracture and is currently recruiting…
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FDA approval · 2024-10-11FDA Approved: XIAFLEX — Supplemental Application (Endo USA, Inc.)
The FDA approved a supplemental application for XIAFLEX (collagenase clostridium histolyticum) submitted by Endo USA, Inc., to modify/expand…
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CLINICAL_TRIALS research · 2024-05-31Clinical Trial Update: Effectiveness of Night Splinting After Percutaneous Needle Fasciotomy in Dupuytren's Contracture [NA]
This clinical trial update describes the ongoing recruitment for evaluating the effectiveness of night splinting after percutaneous needle f…
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FDA approval · 2023-07-12FDA Approved: XIAFLEX — Supplemental Application (Endo USA, Inc.)
The FDA approved a supplemental application for XIAFLEX (collagenase clostridium histolyticum) from Endo USA, Inc.
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CLINICAL_TRIALS trial_result · 2023-05-17Clinical Trial Update: Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture [Phase 4]
Phase 4 clinical trial evaluating percutaneous needle fasciotomy with or without corticosteroid injection for Dupuytren's Contracture is cur…
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FDA approval · 2022-06-09FDA Approved: XIAFLEX — Supplemental Application (Endo USA, Inc.)
The FDA approved a supplemental application for XIAFLEX (collagenase clostridium histolyticum) submitted by Endo USA, Inc., representing an …
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CLINICAL_TRIALS trial_result · 2022-04-26Clinical Trial Update: Dupuytren´s Disease Study. Primary Disease, MCP Joint, Xiapex, PNF [Phase 4]
Phase 4 clinical trial update for Dupuytren Contracture evaluating Xiapex with PNF; study completed.
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CLINICAL_TRIALS trial_result · 2021-06-01Clinical Trial Update: The Role of Tranexamic Acid in Reducing Post Operative Hand Edema After Hand and Wrist Surgery [Phase 4]
Phase 4 clinical trial evaluating tranexamic acid to reduce postoperative hand edema after hand and wrist surgery.
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FDA approval · 2021-04-13FDA Approved: XIAFLEX — Supplemental Application (Endo USA, Inc.)
FDA approved a supplemental application for Xiaflex (collagenase clostridium histolyticum) submitted by Endo USA, Inc. The approval expands …
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EMA withdrawal · 2020-03-02EMA Withdrawn: Xiapex (collagenase Clostridium histolyticum) — Swedish Orphan Biovitrum AB
The EMA has withdrawn Xiapex (collagenase Clostridium histolyticum) from the market for Dupuytren Contracture by Swedish Orphan Biovitrum AB…
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CLINICAL_TRIALS trial_result · 2019-09-26Clinical Trial Update: Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery [Phase 2]
Phase 2 trial comparing ibuprofen plus acetaminophen vs oxycodone alone after hand surgery to assess pain control and recovery outcomes.
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CLINICAL_TRIALS trial_result · 2018-06-29Clinical Trial Update: Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data
A completed University of Oxford analysis using routine data to describe the epidemiology and outcomes of upper limb surgeries, covering a r…