Down Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-01-29Clinical Trial Update: A 4-Week Safety Study of Oral ELND005 in Young Adults With Down Syndrome Without Dementia [Phase 2]
Phase 2 safety study of oral ELND005 in young adults with Down syndrome without dementia completed.
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CLINICAL_TRIALS trial_result · 2016-01-20Clinical Trial Update: Can Increased Body Mass Index Prevent Adequate Ultrasound Examination for Trisomy 21 Risk Assessment?
The completed study from Benha University evaluated whether higher body mass index affects the adequacy of ultrasound examinations used in t…
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CLINICAL_TRIALS trial_result · 2015-09-17Clinical Trial Update: Clinical Performance of the MaterniT21 PLUS LDT in Multiple Gestation Pregnancies
Clinical trial update reporting the clinical performance of the MaterniT21 PLUS LDT in multiple gestation pregnancies.
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: A Molecular and Functional Brain Imaging Study in Individuals With Down Syndrome and Healthy Controls Following Single Dose RG1662 [Phase 1]
A Phase 1 brain imaging study evaluating a single dose of RG1662 in individuals with Down syndrome and healthy controls; the study has compl…
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CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: Evaluation of a Simplified Method for Diagnosis of Sleep Apnea in Children and Adults With Down Syndrome
A completed clinical trial evaluated a simplified method for diagnosing sleep apnea in individuals with Down syndrome.
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CLINICAL_TRIALS trial_result · 2015-06-03Clinical Trial Update: A New Prenatal Blood Test for Down Syndrome
A completed clinical trial evaluating a new prenatal blood test for detecting Down syndrome (trisomy 21) in fetuses has been reported.
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CLINICAL_TRIALS trial_result · 2015-03-12Clinical Trial Update: Rivastigmine Study in Adolescents With Down Syndrome [Phase 1, Phase 2]
The document reports the completion of a Phase 1/2 clinical trial of rivastigmine in adolescents with Down syndrome. Results were posted in …
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CLINICAL_TRIALS trial_result · 2015-03-05Clinical Trial Update: Effects of Whole-body Vibration Training on Body Composition in Adolescents With and Without Down Syndrome [NA]
A completed clinical trial examining how whole-body vibration training affects body composition in adolescents with Down syndrome compared t…
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CLINICAL_TRIALS trial_result · 2015-03-03Clinical Trial Update: A Study of RG1662 in Individuals With Down Syndrome [Phase 1]
A Phase 1 study of RG1662 in individuals with Down syndrome has completed.
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CLINICAL_TRIALS trial_result · 2014-11-07Clinical Trial Update: An Interactive Informed Consent and Education Program for Pregnant Women [Phase 1]
Phase 1 completed trial of an interactive informed consent and education program for pregnant women. The study included considerations relat…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: Use of eHealth in Communication With Patients About Prenatal Diagnosis [NA]
Final results from a completed clinical trial evaluating how eHealth tools can be used to communicate with patients about prenatal diagnosis…
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CLINICAL_TRIALS trial_result · 2014-07-14Clinical Trial Update: Non-invasive Chromosomal Examination of Trisomy Study
The trial update notes the completion of Roche Sequencing Solutions' Non-invasive Chromosomal Examination of Trisomy Study, which investigat…
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CLINICAL_TRIALS trial_result · 2014-01-28Clinical Trial Update: Phase II Study of Florbetaben (BAY94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid. [Phase 2]
Phase II trial evaluating Florbetaben PET imaging (BAY94-9172) for detection/exclusion of cerebral beta-amyloid; study completed with result…
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CLINICAL_TRIALS trial_result · 2014-01-28Clinical Trial Update: A Bicycle Training Intervention [NA]
This update notes the completion of a bicycle training intervention clinical trial conducted by the University of Michigan in individuals wi…
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CLINICAL_TRIALS trial_result · 2014-01-24Clinical Trial Update: Treadmill Training and Orthotic Use in Infants With Down Syndrome [NA]
This clinical trial update reports that the study evaluating treadmill training and orthotic use in infants with Down syndrome is completed …
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CLINICAL_TRIALS trial_result · 2013-12-30Clinical Trial Update: Gait in Children With Down Syndrome While Wearing Orthoses [NA]
A completed clinical trial studied gait in children with Down syndrome while wearing orthoses, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-07-16Clinical Trial Update: Comparison of Aneuploidy Risk Evaluations
This clinical trial update reports on a completed study comparing methods for evaluating fetal aneuploidy risk in pregnancy, including Down …
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CLINICAL_TRIALS trial_result · 2013-07-02Clinical Trial Update: Non-invasive Prenatal Diagnostic Validation Study
The study completed validation of a non-invasive prenatal diagnostic test for fetal chromosomal abnormalities.
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CLINICAL_TRIALS trial_result · 2013-03-13Clinical Trial Update: Egcg, a dyrk1a Inhibitor as Therapeutic Tool for Reversing Cognitive Deficits in Down Syndrome Individuals. [Phase 2]
A Phase 2 clinical trial evaluating EGCG, a DYRK1A inhibitor, as a potential therapy to reverse cognitive deficits in individuals with Down …
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CLINICAL_TRIALS trial_result · 2013-02-13Clinical Trial Update: Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10 [Phase 3]
Phase 3 trial evaluating donepezil for cognitive dysfunction in children with Down syndrome was terminated; results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-02-01Clinical Trial Update: Efficacy and Safety of Memantine Hydrochloride in Enhancing the Cognitive Abilities of Young Adults With Down Syndrome [Phase 4]
Phase 4 trial evaluating memantine hydrochloride for cognitive enhancement in young adults with Down syndrome; results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-01-10Clinical Trial Update: Prenatal Test for Fetal Aneuploidy Detection
Completed clinical trial update on Roche's prenatal test for fetal aneuploidy detection, including Down syndrome (Trisomy 21).
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CLINICAL_TRIALS trial_result · 2013-01-01Clinical Trial Update: Eyelash Line Resection for Entropion Associated With Down's Syndrome [NA]
A completed clinical trial assessing eyelash line resection to correct entropion in individuals with Down syndrome.
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CLINICAL_TRIALS trial_result · 2012-11-28Clinical Trial Update: Efficacy of Rivastigmine in Patients With Down Syndrome [NA]
A completed clinical trial assessed the efficacy of rivastigmine in patients with Down syndrome.
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CLINICAL_TRIALS trial_result · 2012-05-09Clinical Trial Update: Multicenter Vitamin E Trial in Aging Persons With Down Syndrome [Phase 3]
The document reports completion of the multicenter Phase 3 trial of vitamin E in aging individuals with Down syndrome and Alzheimer’s diseas…