Down Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-06-13Clinical Trial Update: Treatment Trial of Subclinical Hypothyroidism in Down Syndrome [NA]
A completed clinical trial evaluating treatment for subclinical hypothyroidism in individuals with Down syndrome; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Gait Parameters of Persons With Down Syndrome With and Without Orthotics Using GaitRite
A completed clinical trial examined gait parameters in individuals with Down syndrome with and without orthotics using the GaitRite system.
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CLINICAL_TRIALS trial_result · 2019-01-09Clinical Trial Update: Down Syndrome Metabolic Health Study
Clinical trial update for a Down Syndrome metabolic health study (NCT01821300) completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: Obstructive Sleep Apnea and Down Syndrome: Clinical Examination Issue [NA]
A completed clinical trial update related to obstructive sleep apnea in individuals with Down syndrome, noting a clinical examination issue.
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: Phenotypic Specific Communication Intervention for Children With Down Syndrome [NA]
The Vanderbilt University-sponsored study evaluating a phenotypic-specific communication intervention for children with Down syndrome has co…
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CLINICAL_TRIALS trial_result · 2018-06-12Clinical Trial Update: Indicators of Growth, Nutritional Status and Comorbide Disorders of Newborns With Down Syndrome
A completed clinical trial assessing indicators of growth, nutritional status, and comorbidities in newborns with Down syndrome.
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Treatment of Sleep Disturbances in School-age Children With Down Syndrome [NA]
A clinical trial investigating treatments for sleep disturbances in school-age children with Down syndrome has completed, sponsored by Cinci…
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17 [Phase 3]
Phase 3 trial evaluating donepezil hydrochloride (Aricept) for cognitive dysfunction in children with Down syndrome aged 11 to 17 was termin…
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CLINICAL_TRIALS trial_result · 2017-10-25Clinical Trial Update: A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS) [Phase 2]
A Phase 2 trial of RG1662 in adults and adolescents with Down syndrome (CLEMATIS) has completed.
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CLINICAL_TRIALS trial_result · 2017-10-18Clinical Trial Update: Parent Supported Weight Reduction in Down Syndrome [NA]
A completed clinical trial update examining parent-supported weight reduction for individuals with Down syndrome.
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: A Double-blind, Placebo-controlled Comparative Study and Open-label Extension Study to Confirm the Efficacy and Safety of E2020 in Subjects With Down Syndrome Having Regression Symptoms and Disabled Activities of Daily Living. [Phase 2]
A Phase 2 double-blind, placebo-controlled study with an open-label extension assessing the efficacy and safety of E2020 (donepezil) in indi…
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CLINICAL_TRIALS trial_result · 2017-08-15Clinical Trial Update: T21,18 and 13 Screening by Cell Free Fetal DNA in Low Risk Patients [NA]
A completed clinical trial evaluated cell-free fetal DNA screening for Trisomy 21, 18, and 13 in low-risk pregnancies.
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CLINICAL_TRIALS trial_result · 2017-07-06Clinical Trial Update: A Study of RO5186582 in Down Syndrome Among Children 6 to 11 Years of Age [Phase 2]
A Phase 2 study evaluating RO5186582 for Down syndrome in children aged 6 to 11 was terminated. No results are provided in the available sni…
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CLINICAL_TRIALS trial_result · 2017-05-05Clinical Trial Update: Frequency of Metabolic Syndrome in Down Syndrome Patients
This completed clinical trial examined the frequency of metabolic syndrome in individuals with Down syndrome. The sponsor listed is Universi…
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CLINICAL_TRIALS trial_result · 2017-05-02Clinical Trial Update: Down Syndrome Biomarker Initiative (DSBI)
The Down Syndrome Biomarker Initiative (DSBI) trial has completed, documenting biomarker findings in individuals with Down syndrome and Alzh…
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CLINICAL_TRIALS trial_result · 2017-04-27Clinical Trial Update: Effects of Infant Massage on Acceptance, Commitment and Conscience of Influence of Parents With Down Syndrome Babies [NA]
A clinical trial exploring whether infant massage affects acceptance, commitment, and perceived influence among parents of babies with Down …
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CLINICAL_TRIALS trial_result · 2017-03-21Clinical Trial Update: Effects of Infant Massage on Development of Down Syndrome Babies [NA]
A clinical trial evaluating the effects of infant massage on development in babies with Down syndrome has completed.
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Assessment of Bone Density and Bone Turnover Markers in Patients With Down Syndrome and Comparison to the Ts65Dn Model [NA]
Completed clinical trial evaluating bone density and bone turnover markers in individuals with Down syndrome and comparing results to the Ts…
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Studying DNA in Samples From Younger Patients With Down Syndrome and Acute Myeloid Leukemia Treated on COG-AAML0431 Clinical Trial
A completed analysis within the COG-AAML0431 trial looked at DNA samples from younger patients with Down syndrome and acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: Clinical Evaluation of the SEQureDx T21 Test In High Risk Pregnancies
The document reports a completed clinical evaluation of the SEQureDx T21 test for detecting Down syndrome and fetal aneuploidy in high-risk …
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: Clinical Evaluation of the SEQureDx Trisomy Test in Low Risk Pregnancies
The clinical trial evaluating the SEQureDx Trisomy Test for detecting Down syndrome in low-risk pregnancies has completed.
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CLINICAL_TRIALS trial_result · 2016-03-25Clinical Trial Update: Motor Learning Through Virtual Reality Task in Individuals With Down Syndrome [NA]
A completed clinical trial from the University of Sao Paulo studied motor learning using a virtual reality task in individuals with Down syn…
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Biomarkers in Samples From Patients With Down Syndrome and Acute Megakaryoblastic Leukemia
Clinical trial update summarizing biomarker analyses from samples of patients with Down syndrome-associated acute megakaryoblastic leukemia …
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CLINICAL_TRIALS trial_result · 2016-02-11Clinical Trial Update: Normalization of dyrk1A and APP Function as an Approach to Improve Cognitive Performance and Decelerate AD Progression in DS Subjects: Epigallocatechin Gallate as Therapeutic Tool [Phase 2]
Phase 2 clinical trial update evaluating epigallocatechin gallate (EGCG) to normalize dyrk1A and APP function in individuals with Down syndr…
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CLINICAL_TRIALS trial_result · 2016-02-08Clinical Trial Update: Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome [NA]
A completed clinical trial investigated obstructive sleep apnea and its effects on neurocognitive and cardiovascular function in children wi…