Down Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Amyloid Lowering for Alzheimer's in Down's With Donanemab Investigation [Phase 4]
A Phase 4 clinical trial to evaluate donanemab for amyloid lowering in Alzheimer's disease associated with Down syndrome is not yet recruiti…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Effects of Powerball in Children With Down Syndrome [NA]
This document reports a recruiting clinical trial evaluating the effects of Powerball in children with Down syndrome.
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome [Phase 3]
A Phase 3 clinical trial update from the University of Colorado, Denver investigates sympathetic nervous system function in individuals with…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: The Efficacy of Therapy in Patients With Acute Myeloid Leukemia and Down Syndrome in Russia [Phase 3]
A Phase 3 clinical trial in Russia evaluating the efficacy of a therapy for patients with acute myeloid leukemia and Down syndrome is curren…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: The Effect of the HEP Approach in Infants With Down Syndrome [NA]
A clinical trial update indicates ongoing recruitment for evaluating the HEP Approach in infants with Down syndrome.
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: The Human Trisome Project
Clinical trial update for The Human Trisome Project (NCT02864108) shows the University of Colorado, Denver is currently recruiting participa…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome
This ClinicalTrials.gov study update describes computer modeling of airways in children and young adults with Down syndrome and obstructive …
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Validation of Sleep Questionnaires in the Down Syndrome Population [NA]
This update describes validation of sleep questionnaires for individuals with Down syndrome to assess obstructive sleep apnea, with the stud…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea [Phase 3]
Phase 3 clinical trial evaluating hypoglossal nerve stimulation for cognition and language in individuals with Down syndrome and obstructive…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Prevalence of Translocation Phenotyping in Children With Down Syndrome and Their Parents
The trial aims to determine how often translocation phenotyping is performed in children with Down syndrome and in their parents. The study …
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Evaluation of Fetal Bladder Emptying During the 11-14 Weeks' Ultrasound Examination as a Negative Predictive Marker for Chromosomal Abnormalities
A study evaluating fetal bladder emptying at 11-14 weeks as a negative predictive marker for chromosomal abnormalities, to inform prenatal s…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Drumming Lessons' Influence on Children With Down Syndrome [NA]
A Vanderbilt University study is exploring whether drumming lessons influence outcomes in children with Down syndrome; the trial status is n…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Parent Child Interaction Therapy vs Conventional Parent Led Therapy in Down Syndrome [NA]
A completed clinical trial comparing Parent-Child Interaction Therapy to conventional parent-led therapy in individuals with Down syndrome a…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: PAP for Children With DS and OSAS [NA]
A clinical trial update indicates a study evaluating positive airway pressure therapy for children with Down syndrome and obstructive sleep …
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Using Technologies to Promote HEalthy Lifestyles in Adolescents With Intellectual Disabilities [NA]
A clinical trial update indicates that a University of Seville study aiming to promote healthy lifestyles in adolescents with intellectual d…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: tDCS for Catatonic Depression in Down Syndrome: A Pilot Study [NA]
This clinical trial update describes a pilot study using transcranial direct current stimulation to treat catatonic depression in individual…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Elucidating Age-related Comorbidity Patterns in Down Syndrome (DS)
A completed clinical trial investigating age-related comorbidity patterns in individuals with Down syndrome.
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Neuropsychological Evaluation in Intellectual Disability (ENDI)
ClinicalTrials.gov entry for the ENDI study, a neuropsychological evaluation project in individuals with Down syndrome, currently not yet re…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition [Phase 2]
Phase 2 clinical trial update from Vanderbilt University Medical Center examining cholinergic integrity in individuals with Down syndrome to…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Nutritional Status in Children With Down Syndrome
A planned clinical trial from Assiut University is studying nutritional status in children with Down syndrome and is currently not recruitin…
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Effects of Down Dog Yoga on Pre-writing Skills in Children With Down Syndrome [NA]
This clinical trial is studying whether a yoga program called Down Dog improves pre-writing skills in children with Down syndrome. The trial…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Measuring Aided Language Development [NA]
Clinical trial update from the University of Central Florida evaluating aided language development; recruitment is ongoing for participants …
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Harness-based Mobility Intervention for Infants With Down Syndrome [NA]
A clinical trial evaluating a harness-based mobility intervention for infants with Down syndrome is currently recruiting at Boston Universit…
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Periodontitis and Inflammation in Children With Down Syndrome/Trisomy 21: Study on Biological Samples [NA]
An ongoing recruiting clinical study from Assistance Publique - Hôpitaux de Paris investigates periodontitis and inflammation in children wi…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Relationship Between Eating Patterns, Body Composition and the Detection of Fatty Liver in Children and Adolescents With Trisomy 21: LiverTy Project
Ongoing LiverTy clinical trial in children and adolescents with Down syndrome investigates how eating patterns and body composition relate t…