Down Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Effect of Cognitive-motor Training Versus Pilates Exercises on Postural Stability in Down Syndrome. [NA]
Ongoing clinical trial comparing cognitive-motor training to Pilates exercises to assess effects on postural stability in children with Down…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Adapting RDAD for DS [NA]
A clinical trial update indicates the University of Kansas Medical Center is adapting the RDAD program for individuals with Down syndrome an…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Physical Activity and Community EmPOWERment Project [NA]
Clinical trial update from the University of North Carolina on the Physical Activity and Community Empowerment project. The study is current…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Rebound Therapy on Ventilatory Functions in Down Syndrome [NA]
The trial 'Rebound Therapy on Ventilatory Functions in Down Syndrome' is not yet recruiting and is studying the effects of rebound therapy o…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Proactive Speech and Language Intervention for Infants With Down Syndrome [NA]
This update describes an ongoing clinical trial evaluating proactive speech and language intervention for infants with Down syndrome, sponso…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS) [NA]
This is a clinical trial update for TOPS-DS, describing recruitment for a personalized surgical treatment approach for obstructive sleep apn…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Developing a Down Syndrome Health Instrument
A Massachusetts General Hospital clinical trial has completed development work on a Down syndrome health instrument. The tool is intended to…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Effects of (tDCS) Combined With Virtual Reality Versus CPT on Brain, Cognitive, and GMS in Children With DS. [NA]
A clinical trial is evaluating whether transcranial direct current stimulation (tDCS) plus virtual reality improves brain function, cognitio…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: The Impact of Core Stability Versus Respiratory Muscle Strengthening Exercises on Bone Mineral Density in Children With Down Syndrome [NA]
A ClinicalTrials.gov study comparing core stability to respiratory muscle strengthening exercises to evaluate effects on bone mineral densit…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome [Phase 3]
Phase 3 compassionate-use trial evaluating epithelial-on corneal collagen crosslinking with UVA exposure for eyes with ectatic corneal disea…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Group-based Resistance Training for Adults With Down Syndrome [NA]
A clinical trial update for a group-based resistance training program in adults with Down syndrome, noting the study is active but not recru…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Immune Profile and Respiratory Parameters in Down Syndrome Children With Acute Pneumonia: Pre-Intervention Analysis
A clinical trial assessing immune profiles and respiratory parameters in Down syndrome children with acute pneumonia before any intervention…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Effects of Chronic Creatine and Beta-Hydroxy-Beta-Methylbutyrate Supplementation on Oxidative Stress, Inflammation, Muscle Strength, and Body Composition in Individuals With Down Syndrome [NA]
This clinical trial is evaluating the effects of chronic creatine and beta-hydroxy-beta-methylbutyrate supplementation on oxidative stress, …
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: LEvetiracetam to Prevent Seizures in Symptomatic Alzheimer's Disease in Adults With Down Syndrome [Phase 3]
A Phase 3 clinical trial is evaluating whether Levetiracetam can prevent seizures in adults with Down syndrome who have symptomatic Alzheime…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Optimizing the Management of OSA in Children With Down Syndrome
This clinical trial, sponsored by University Hospital Strasbourg, aims to optimize the management of obstructive sleep apnea in children wit…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: A Multicenter Retrospective Analysis of Postoperative Respiratory Complications in Children With Obstructive Sleepapnea
A multicenter retrospective study examining postoperative respiratory complications in children with obstructive sleep apnea, currently recr…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Phenolic Complex k110-42 Therapy on Cognitive Functions in Down Children [Phase 3]
A Phase 3 clinical trial evaluating Phenolic Complex k110-42 for cognitive function in children with Down syndrome; the study is not yet rec…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study) [Phase 1, Phase 2]
This clinical trial update indicates that AC Immune's Alzheimer’s-focused candidate ACI-24.060 is being evaluated in Phase 1 and Phase 2 stu…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Sensitivity of the NIH Toolbox to Stimulant Treatment in Intellectual Disabilities [Phase 1]
Phase 1 clinical trial update evaluating how sensitive the NIH Toolbox is to stimulant treatment in individuals with intellectual disabiliti…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down Syndrome [Phase 1]
Phase 1 clinical trial evaluating NAD augmentation to prevent or reverse Alzheimer's disease in people with Down syndrome; currently not yet…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Role of Early Motor Experience in Infants With Down Syndrome [NA]
This document reports on a completed clinical trial conducted by Georgia State University examining the role of early motor experience in in…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Leucettinib-21 First-in-Human Phase 1 in Healthy Volunteers and Subjects With Down Syndrome and Alzheimer's Disease [Phase 1]
A first-in-human Phase 1 study of Leucettinib-21 is enrolling healthy volunteers and individuals with Down syndrome and Alzheimer's disease.…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Cervical Spine Abnormalities in Down Syndrome
This clinical trial update from Sohag University examines cervical spine abnormalities in people with Down syndrome. The study is currently …
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Effects of Vojta Therapy on Functional Mobility and Gait Parameters in Children With Down Syndrome [NA]
A clinical trial is investigating the effects of Vojta Therapy on functional mobility and gait in children with Down syndrome and is current…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Physical Fitness in DS: A Comparison of Cuevas Medak and Rebound Exercises [NA]
This clinical trial compares Cuevas Medak and rebound exercises to evaluate physical fitness in individuals with Down syndrome; recruitment …