Down Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-27Clinical Trial Update: Developing a Down Syndrome Health Instrument
A completed clinical trial evaluating a health instrument for individuals with Down syndrome, with results posted.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without Thymectomy
A recruiting clinical study investigating immune system aging and dysregulation in people with Down syndrome, comparing those who have under…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Patterns of Neurodevelopmental Disorders
This clinical trial update reports that a Richard Frye-sponsored study on patterns of neurodevelopmental disorders, including autism spectru…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Escalating Doses of Memantine in Down Syndrome (MEDS-123) [Phase 1]
Phase 1 clinical trial from University Hospitals Cleveland Medical Center evaluating escalating doses of memantine in individuals with Down …
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Qualitative Effects of AEF0217 in Down Syndrome People
An ongoing study assessing qualitative effects of the experimental drug AEF0217 in people with Down syndrome.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: AEF0217 in Participants With Down Syndrome [Phase 2]
Aelis Farma's Phase 2 trial of AEF0217 in participants with Down syndrome is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome [Phase 2]
A Phase 2 clinical trial sponsored by the University of Arizona is evaluating medications to improve cognition in children with Down syndrom…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Endotype DIrected Treatment for OSA in Down Syndrome [Phase 4]
A Phase 4 clinical trial is recruiting to evaluate endotype-directed treatment for obstructive sleep apnea in individuals with Down syndrome…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Trial-Ready Cohort-Down Syndrome (TRC-DS)
The clinical trial update indicates the Trial-Ready Cohort-Down Syndrome (TRC-DS) at the University of Southern California is currently recr…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Oro-myofunctional Characteristics and Obstructive Sleep Apnea in Infants With Down Syndrome
This clinical trial update notes an ongoing study examining oro-myofunctional characteristics and obstructive sleep apnea in infants with Do…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Gamma Frequency Stimulation in Individuals With Down Syndrome [NA]
An update on a clinical trial studying gamma frequency stimulation in individuals with Down syndrome, currently recruiting.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome [NA]
A clinical trial update for HomeGrown, a family-based lifestyle intervention designed to support healthy development in young children with …
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders
Clinical trial update on an intensive multimodal neurorehabilitation program aimed at enhancing neuroplasticity in pediatric neurodevelopmen…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Metric-Optimized Spectacle Prescriptions for Children With Down Syndrome [Phase 2]
A Phase 2 clinical trial in children with Down syndrome to optimize spectacle prescriptions for refractive error correction and improved vis…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Effects of the Otago Exercise Program on Balance, Endurance, and Motor Coordination in Children With Down Syndrome [NA]
The trial is currently recruiting and will evaluate the Otago Exercise Program's effects on balance, endurance, and motor coordination in ch…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Sleep Intervention and Quality of Life in Down Syndrome [NA]
A clinical trial at the University of Alabama at Birmingham is recruiting participants to study a sleep intervention and its effect on quali…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Qualitative Exploratory Study Among Reunionese Women and Their Partners Who Have a Child With Trisomy 21
A completed qualitative exploratory study conducted in Reunion Island examining the experiences of Reunionese women and their partners who h…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Using Personal Mobile Technology to Identify Obstructive Sleep Apnea in Children With Down Syndrome (UPLOAD)
This clinical trial investigates using personal mobile technology to identify obstructive sleep apnea in children with Down syndrome. The st…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia [NA]
A University of Michigan clinical trial is recruiting to evaluate a self-supporting nasopharyngeal airway device for treating upper airway o…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Brain Outcomes With Lifestyle Change in Down Syndrome [NA]
A clinical trial is currently recruiting to assess how lifestyle changes affect brain outcomes in people with Down syndrome, with potential …
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography
Clinical trial entry for an observational study evaluating diastolic function in newborns during the transitional period and infancy using s…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Therapies for Down Syndrome Regression Disorder [Phase 2]
Phase 2 clinical trial update for therapies addressing Down Syndrome Regression Disorder. The study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: The Neurocognitive Bases of Trust in Intellectual Disability
A clinical trial update describing research into the neurocognitive bases of trust in individuals with intellectual disability, focusing on …
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
A clinical trial update describing a study to learn more about the health of persons with Down syndrome after treatment for acute leukemia.
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Effects of Jump Rope on Navicular Drop in Down Syndrome [NA]
A recruiting clinical trial is evaluating whether a jump rope exercise program can affect navicular drop in individuals with Down syndrome.