Dihydropyrimidine Dehydrogenase Deficiency
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: The PhOCus Trial: Implementation of Pharmacogenomic Testing in Oncology Care [NA]
This clinical trial update describes implementing pharmacogenomic testing in oncology care to guide treatment decisions, with focus on gastr…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Safety of Trifluridine/Tipiracil in Patients With Dihydropyrimidine Dehydrogenase Deficiency Diagnosed With Metastatic Colorectal or Gastroesophageal Cancer [Phase 2]
Phase 2 trial investigating the safety of trifluridine/tipiracil (Lonsurf) in patients with dihydropyrimidine dehydrogenase (DPD) deficiency…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Nudge Strategies for DPYD Testing in Patients With Gastrointestinal Cancers Treated With Fluoropyrimidines [NA]
A completed clinical trial evaluated nudge strategies to increase DPYD testing before fluoropyrimidine therapy in patients with gastrointest…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders
The NHGRI-sponsored study is a natural history project to understand clinical, genomic, pharmacological, laboratory, and dietary factors in …