Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Chidamide Plus R-CHOP in Newly Diagnosed Double-Expressor Diffuse Large B-Cell Lymphoma With Other Molecular Subtypes [Phase 2]
This Phase 2 clinical trial assesses chidamide in combination with R-CHOP for newly diagnosed double-expressor diffuse large B-cell lymphoma…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: CHiR Therapy for Elderly DLBCL Intolerant to Chemo [Phase 2]
Phase 2 clinical trial evaluating CHiR Therapy for elderly patients with diffuse large B-cell lymphoma intolerant to chemotherapy is current…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Clinical Study of HiR+X Therapy for Newly Diagnosed Elderly Patients With DLBCL Intolerant to Chemotherapy [Phase 2]
A Phase 2 clinical trial of HiR+X Therapy for newly diagnosed elderly patients with Diffuse Large B-Cell Lymphoma who are intolerant to chem…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Hypofractionation Radiotherapy in Combination with Glofitamab in Relapsed/refractory Diffuse B-cell Lymphoma with Baseline High Tumor Burden [Phase 2]
Phase 2 trial evaluating hypofractionated radiotherapy in combination with glofitamab for relapsed/refractory diffuse large B-cell lymphoma …
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Glofitamab Combination With Chidamide in Patients With Recurrent/Refractory DLBCL [Phase 2]
Phase 2 trial evaluating the combination of glofitamab and chidamide for recurrent or refractory diffuse large B-cell lymphoma is currently …
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: Connect® Lymphoma Disease Registry: A US-Based Prospective Observational Cohort Study
A US-based observational lymphoma registry sponsored by Celgene has been terminated.
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: Multidisciplinary Care Program to Secure MEdication Therapy for HematoLOgy Patients Receiving Injectable Anticancer Drugs
A completed clinical trial evaluating a multidisciplinary care program to ensure medication therapy for hematology patients receiving inject…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: A Study of RNK05047 in Subjects With Advanced Solid Tumors/Diffuse Large B-cell Lymphoma (CHAMP-1) [Phase 1, Phase 2]
CHAMP-1 is a Phase 1/2 study evaluating RNK05047 in adults with advanced solid tumors or diffuse large B-cell lymphoma, currently recruiting…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: CD70-targeted immunoPET Imaging of Malignant Cancers [NA]
A clinical trial evaluating CD70-targeted immunoPET imaging in multiple cancers is currently recruiting, including renal cell carcinoma, dif…
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CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: The Incidence of Hepatitis B in Diffuse Large B-Cell Lymphoma/Chronic Lymphoid Leukemia HBsAg-positive Treated With Rituximab, Chemotherapy and Tenofovir Alafenamide [Phase 2]
A Phase 2 trial evaluating the incidence of hepatitis B in HBsAg-positive patients with diffuse large B-cell lymphoma or chronic lymphocytic…
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CLINICAL_TRIALS withdrawal · 2025-02-21Clinical Trial Update: QUILT-3.061: CD19 t-haNK in Subjects With Diffuse Large B-Cell Lymphoma [Phase 1]
A Phase 1 trial of CD19 t-haNK for diffuse large B-cell lymphoma has been withdrawn.
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Lenalidomide Combined With G-CHOP in the Treatment of Newly Diagnosed DLBCL With FL [Phase 2]
A Phase 2 clinical trial evaluating lenalidomide in combination with G-CHOP for newly diagnosed diffuse large B-cell lymphoma with follicula…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: AZA Combined With RCHOP in P53-mutated DLBCL. [Phase 2]
Phase 2 clinical trial evaluating azacitidine in combination with the R-CHOP regimen for TP53-mutated diffuse large B-cell lymphoma, current…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: A Multicenter, Prospective, Real-world Study of a Regimen Containing Tucidinostat for Primary Treatment of DLBCL
A multicenter prospective real-world study evaluating a tucidinostat-containing regimen as first-line treatment for diffuse large B-cell lym…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Study of Pomalidomide Combination with Rituximab and Anti-PD-1 Antibody （PPR） in Third or Later Line Therapy of DLBCL [NA]
This clinical trial update describes a study of pomalidomide with rituximab and an anti-PD-1 antibody (PPR) for third- or later-line diffuse…
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: NKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell Lymphoma [Phase 2, Phase 3]
A Phase 2/3 clinical trial of NKTR-255 after CD19-directed CAR-T therapy in relapsed/refractory large B-cell lymphoma has been terminated.
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Multicenter Retrospective Observational Study of Relapsed Diffuse Large B-Cell Lymphoma Presenting As Indolent Lymphoma
This clinical trial update notes a multicenter retrospective observational study evaluating relapsed Diffuse Large B-Cell Lymphoma presentin…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Relmacabtagene Autoleucel As Second-Line Therapy in Adult Patients with Aggressive B-cell NHL [Phase 2]
A Phase 2 clinical trial evaluating Relmacabtagene autoleucel as second-line therapy for adults with aggressive B-cell non-Hodgkin lymphomas…
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: Telehealth-based Symptom Management for Veterans Treated With Selinexor
ClinicalTrials.gov update indicates a telehealth-based symptom management study for veterans treated with selinexor is currently active but …
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: A Safety Study of SEA-TGT (SGN-TGT) in Advanced Cancer [Phase 1]
Seagen's SEA-TGT (SGN-TGT) Phase 1 safety study in advanced cancers has been terminated. The study enrolled patients across multiple cancer …
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: A Study of Evaluating the Safety and Efficacy of ATG-010 in Relapsed/Refractory Diffuse Large B-Cell Lymphoma [Phase 2]
Phase 2 trial evaluating ATG-010 for safety and efficacy in relapsed/refractory diffuse large B-cell lymphoma has completed, with results po…
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: ME-401 and R-CHOP in Newly Diagnosed Diffuse Large B-Cell Lymphoma [Phase 1, Phase 2]
The Phase 1/2 study of ME-401 in combination with R-CHOP for newly diagnosed Diffuse Large B-Cell Lymphoma was terminated, with results post…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Sequential Treatment of CD19 CARNK and 7x19 CAR-T in R/R B Cell Lymphoma [Phase 1]
A Phase 1 trial assessing sequential administration of CD19 CAR-NK cells followed by 7x19 CAR-T cells in relapsed/refractory B-cell lymphoma…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Prospective Analysis of Circulating Nucleosomes in Patients Receiving a First Line Treatment for a Non-Hodgkin Lymphoma [NA]
A prospective analysis of circulating nucleosomes in patients receiving first-line treatment for non-Hodgkin lymphoma, including Follicular …
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CLINICAL_TRIALS research · 2025-02-04Clinical Trial Update: Polatuzumab, Rituximab and Orelabrutinib Combination Regimen (PRO) in the Treatment of Elderly Frail Patients with Treatment-naive Non-GCB DLBCL [Phase 2]
This is a Phase 2 clinical trial evaluating a three-drug regimen of polatuzumab vedotin, rituximab, and orelabrutinib for elderly, frail pat…