Diffuse Large B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Comprehensive Geriatric Assessment to Predict Toxic Events in Older Patients With Non-Hodgkin Lymphoma With Imbedded Pilot Study of Pre-Phase Therapy [NA]
Clinical trial update on evaluating comprehensive geriatric assessment to predict toxic events in older patients with Non-Hodgkin lymphoma, …
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Zanubrutinib, Lenalidomide and Rituximab (ZR2) in Elderly Treatment-naive Patients With Diffuse Large B-cell Lymphoma (DLBCL) [Phase 2]
Phase 2 trial update for Zanubrutinib, Lenalidomide and Rituximab (ZR2) in elderly, treatment-naive Diffuse large B-cell lymphoma. The study…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Glofitamab for Consolidation After First-line Treatment of High-risk Large B-cell Lymphoma [Phase 4]
This clinical trial update reports a Phase 4 study of glofitamab as consolidation after first-line therapy in patients with high-risk diffus…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: A Phase 1/2 Study of IDP-121 in Patients With Relapsed/Refractory Hematologic Malignancies [Phase 1, Phase 2]
IDP-121 is being studied in a Phase 1/2 trial for relapsed/refractory hematologic malignancies and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: Abexinostat and Ibrutinib in Diffuse Large B-cell Lymphoma and Mantle Cell Lymphoma [Phase 1]
A Phase 1 trial evaluating the combination of Abexinostat and Ibrutinib in diffuse large B-cell lymphoma and mantle cell lymphoma has comple…
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: Zanubrutinib Combined With Standard Chemotherapy in the Treatment for Patients With Diffuse Large B Cell Lymphoma [Phase 2]
A Phase 2 trial of Zanubrutinib combined with standard chemotherapy for diffuse large B-cell lymphoma is suspended. The study lists CD79A/B …
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CLINICAL_TRIALS other · 2025-04-24Clinical Trial Update: DALY II USA/ MB-CART2019.1 for DLBCL [Phase 2]
Miltenyi Biomedicine's MB-CART2019.1 (DALY II) is in Phase 2 for refractory/relapsed B-cell lymphomas, including Diffuse Large B-Cell Lympho…
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CLINICAL_TRIALS trial_result · 2025-04-23Clinical Trial Update: 89Zr-DFO-REGN3767 in PET Scans in People With Diffuse Large B Cell Lymphoma (DLBCL) [EARLY_Phase 1]
An early-phase (Phase 1) trial evaluating the PET imaging agent 89Zr-DFO-REGN3767 in patients with diffuse large B-cell lymphoma has complet…
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Axicabtagene Ciloleucel Injection as First-Line Therapy of High-Risk Large B-Cell Lymphoma [NA]
A clinical trial is evaluating axicabtagene ciloleucel as first-line therapy for high-risk diffuse large B-cell lymphoma, with recruitment n…
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Pembrolizumab With Rituximab or Obinutuzumab in Treating Patients With Relapsed or Refractory Follicular Lymphoma or Diffuse Large B Cell Lymphoma [Phase 2]
A Phase 2 trial evaluating pembrolizumab in combination with rituximab or obinutuzumab for relapsed or refractory follicular lymphoma or dif…
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas [Phase 1, Phase 2]
Clinical trial update on a Phase I/II study evaluating the safety of autologous CD20 CAR-T cells in relapsed or refractory B-cell non-Hodgki…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Radiation Dose Optimization in Diffuse Large B- Cell Lymphoma. [NA]
This clinical trial update notes recruitment for a study on optimizing radiation dose in diffuse large B-cell lymphoma, a form of non-Hodgki…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: A Study of R-mini-MCOP in the Treatment of Elderly, Previously Untreated DLBCL [Phase 2]
This entry describes a Phase 2 clinical trial evaluating R-mini-MCOP in elderly, previously untreated diffuse large B-cell lymphoma, which i…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Mixed Molecular Clinical Index (MMCI) in Diffuse Large B-cell Lymphoma (DLBCL)
A clinical trial is currently recruiting to evaluate the Mixed Molecular Clinical Index (MMCI) in patients with diffuse large B-cell lymphom…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Study to Evaluate Efficacy and Safety of Oral Abexinostat in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL) [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of oral abexinostat in patients with relapsed or refractory diffuse large B-cell l…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Study of Loncastuximab Tesirine in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) or High-Grade B-Cell Lymphoma (HGBCL) Following CAR-T Therapy Failure [Phase 2]
A Phase 2 clinical trial evaluating loncastuximab tesirine in patients with relapsed or refractory diffuse large B-cell lymphoma or high-gra…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Autologous CD19 CAR-T Cell Therapy (SYNCAR-001) + Orthogonal IL-2 (STK-009) in Subjects With CD19+ Hematologic Malignancies [Phase 1]
Phase 1 study evaluating autologous CD19 CAR-T cell therapy SYNCAR-001 with orthogonal IL-2 STK-009 in CD19-positive hematologic malignancie…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Molecular Monitoring With Circulating Tumor DNA and Nivolumab Maintenance [EARLY_Phase 1]
This update covers an early-phase trial evaluating circulating tumor DNA monitoring and nivolumab maintenance in Diffuse Large B-Cell Lympho…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Safety and Efficacy of R-CMOP Versus R-CHOP in the Initial Treatment of DLBCL [Phase 1, Phase 2]
A Phase 1/2 clinical trial comparing R-CMOP versus R-CHOP as initial therapy for Diffuse Large B-Cell Lymphoma; the study is currently recru…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Safety and Efficacy of Early Second Infusion of Axi-cel Based on ctDNA for R/R Large B - Cell Lymphoma [Phase 1, Phase 2]
This clinical trial update assesses the safety and efficacy of an early second infusion of axicabtagene ciloleucel guided by ctDNA for relap…
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Chimeric Antigen Receptor (CAR) T Cell Therapy With YESCARTA in the Outpatient Setting [Phase 4]
This Phase 4 trial assesses outpatient administration of Yescarta (axicabtagene ciloleucel) for large B-cell lymphoma, including diffuse lar…
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: Epcoritamab-CAR T Cells for Large B-cell Lymphomas [Phase 2]
Phase 2 clinical trial evaluating epcoritamab-CAR T cells for large B-cell lymphomas, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Avelumab, Utomilumab, Rituximab, Ibrutinib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma or Mantle Cell Lymphoma [Phase 1]
Phase 1 trial evaluating avelumab, utomilumab, rituximab, ibrutinib, and chemotherapy in patients with relapsed or refractory diffuse large …
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Zanubrutinib, Chidamide, and Rituximab Induction With or Without CHOP Versus R-CHOP in Newly Diagnosed Double-Expressor DLBCL [Phase 2]
Phase 2 trial evaluating induction with Zanubrutinib, Chidamide, and Rituximab with or without CHOP versus R-CHOP in newly diagnosed double-…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Clinical Trial of TQB2825 Injection Combined With Chemotherapy in Subjects With Diffuse Large B-cell Lymphoma [Phase 2]
A Phase 2 clinical trial evaluating TQB2825 injection in combination with chemotherapy for diffuse large B-cell lymphoma is currently recrui…