Diffuse Cutaneous Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-12-04Clinical Trial Update: Phenotyping of Chronic Pain in Diffused Systemic Scleroderma [NA]
A clinical trial investigating chronic pain phenotypes in diffuse cutaneous systemic sclerosis has completed.
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: US Zamto-cel Autoimmune Diseases [Phase 1]
Miltenyi Biomedicine reports a Phase 1 trial of Zamto-cel for autoimmune diseases including lupus nephritis, systemic lupus erythematosus, s…
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: Safety and Tolerability Study of AVID200 in Pts With Diffuse Cutaneous Systemic Sclerosis [Phase 1]
AVID200's Phase 1 safety and tolerability study in patients with diffuse cutaneous systemic sclerosis has completed.
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: Open Label Extension Study of Brentuximab Vedotin in Early dcSSc [Phase 2]
Open-label extension study of Brentuximab Vedotin for early diffuse cutaneous systemic sclerosis; Phase 2, currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: Exercise With Scleroderma Functional Outcomes [NA]
A completed clinical trial evaluating the effects of an exercise program on functional outcomes in patients with systemic sclerosis (sclerod…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Brentuximab Vedotin for Systemic Sclerosis [Phase 1, Phase 2]
A clinical trial update reports completion of Phase 1/2 studies evaluating Brentuximab Vedotin for diffuse cutaneous systemic sclerosis (scl…
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CLINICAL_TRIALS trial_result · 2024-04-19Clinical Trial Update: A Study With TEPEZZA in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc) [Phase 1]
A Phase 1 study of teprotumumab (TEPEZZA) for diffuse cutaneous systemic sclerosis was terminated, and results were posted on 2024-04-19.
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CLINICAL_TRIALS trial_result · 2024-02-05Clinical Trial Update: Safety and Pharmacokinetics of IgPro20 and IgPro10 in Adults With Systemic Sclerosis (SSc) [Phase 2]
Phase 2 clinical trial evaluating safety and pharmacokinetics of IgPro20 and IgPro10 in adults with diffuse cutaneous systemic sclerosis has…
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CLINICAL_TRIALS trial_result · 2023-10-04Clinical Trial Update: Brentuximab Vedotin in Early Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 trial update for Brentuximab Vedotin in early diffuse cutaneous systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2023-08-30Clinical Trial Update: KD025 in Subjects With Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 clinical trial update for KD025 in diffuse cutaneous systemic sclerosis is terminated with results posted.
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CLINICAL_TRIALS trial_result · 2023-06-05Clinical Trial Update: Efficacy and Safety of Belumosudil in Subjects With Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 trial update on belumosudil for diffuse cutaneous systemic sclerosis; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2021-05-24Clinical Trial Update: Proof of Mechanism Study of GSK2330811 in Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 proof-of-mechanism study of GSK2330811 in diffuse cutaneous systemic sclerosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-03-29Clinical Trial Update: Trial to Evaluate Efficacy and Safety of Lenabasum in Diffuse Cutaneous Systemic Sclerosis [Phase 3]
Phase 3 trial evaluating lenabasum for diffuse cutaneous systemic sclerosis has been terminated.
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CLINICAL_TRIALS trial_result · 2020-08-12Clinical Trial Update: Atorvastatin for Microvascular Endothelial Function and Raynaud in Early Diffuse Scleroderma [Phase 2]
Phase 2 trial investigating atorvastatin for microvascular endothelial function and Raynaud phenomenon in early diffuse cutaneous systemic s…
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CLINICAL_TRIALS trial_result · 2019-06-18Clinical Trial Update: A Study of Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 clinical trial evaluating subcutaneous abatacept for diffuse cutaneous systemic sclerosis has completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-03-04Clinical Trial Update: Proof-of-concept Trial of IVA337 in Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 proof-of-concept trial of IVA337 in diffuse cutaneous systemic sclerosis (scleroderma) completed.
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CLINICAL_TRIALS trial_result · 2018-10-02Clinical Trial Update: Safety, Tolerability, Efficacy, and Pharmacokinetics of JBT-101 in Systemic Sclerosis [Phase 2]
Phase 2 trial of JBT-101 in diffuse cutaneous systemic sclerosis was terminated with posted results.
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: IVIG Treatment in Systemic Sclerosis [NA]
Clinical trial update on intravenous immunoglobulin (IVIG) treatment for systemic sclerosis, including the diffuse cutaneous form; the trial…
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CLINICAL_TRIALS trial_result · 2018-05-01Clinical Trial Update: IL1-TRAP, Rilonacept, in Systemic Sclerosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports on IL1-TRAP (rilonacept) for systemic sclerosis (scleroderma), with the study completed and result…
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CLINICAL_TRIALS withdrawal · 2016-07-22Clinical Trial Update: A Double-Blinded Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986020 Versus Placebo in Diffuse Cutaneous Systemic Sclerosis (dcSSc) [Phase 2]
A Phase 2 double-blind trial evaluating BMS-986020 versus placebo in diffuse cutaneous systemic sclerosis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Treatment Outcome in Early Diffuse Cutaneous Systemic Sclerosis
Clinical trial update reporting treatment outcomes in early diffuse cutaneous systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2016-04-11Clinical Trial Update: Rapamycin vs Methotrexate in Diffuse SSc [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial comparing rapamycin versus methotrexate in diffuse systemic sclerosis.
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CLINICAL_TRIALS trial_result · 2015-04-24Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Abatacept in Patients With Diffuse Systemic Sclerosis (Scleroderma) [Phase 1, Phase 2]
Completed Phase 1/2 study evaluating abatacept for diffuse systemic sclerosis (scleroderma); results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-03-05Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of CAT-192 (Human Anti-TGF-Beta1 Monoclonal Antibody) in Patients With Early Stage Diffuse Systemic Sclerosis [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial update reports safety, tolerability, and pharmacokinetics data for CAT-192, a human anti-TGF-beta1 monoclon…
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CLINICAL_TRIALS trial_result · 2012-03-07Clinical Trial Update: Proof of Concept Trial of Gleevec (Imatinib) in Active Diffuse Scleroderma [Phase 2]
A Phase 2 proof-of-concept trial of imatinib (Gleevec) in active diffuse systemic sclerosis (scleroderma) has been terminated.