Diffuse Cutaneous Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Upfront Autologous HSCT Versus Immunosuppression in Early Diffuse Cutaneous Systemic Sclerosis [Phase 4]
A Phase 4 trial comparing upfront autologous hematopoietic stem cell transplantation to immunosuppression in early diffuse cutaneous systemi…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis [Phase 2]
A Phase 2 multicenter trial assessing HZN-825 in diffuse cutaneous systemic sclerosis has been terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Efficacy of Tofacitinib on Skin Thickening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With Methotrexate [Phase 4]
Phase 4 trial evaluating the efficacy of tofacitinib on skin thickening in diffuse cutaneous systemic sclerosis, compared with methotrexate;…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: An Open-label Extension Trial of HZNP-HZN-825-301 in Adult Participants With Diffuse Cutaneous Systemic Sclerosis (Diffuse Cutaneous SSc) [Phase 2]
An open-label extension trial of HZNP-HZN-825-301 in adults with diffuse cutaneous systemic sclerosis was terminated; results have been post…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease [Phase 1]
A Phase 1 safety and efficacy study of CTX112 in adults with refractory autoimmune diseases, including systemic lupus erythematosus and syst…
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CLINICAL_TRIALS trial_result · 2025-11-03Clinical Trial Update: Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 results from a study evaluating MT-7117 for efficacy, safety, and tolerability in diffuse cutaneous systemic sclerosis have been pos…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis [Phase 2]
Phase 2 clinical trial evaluating autologous stem cell transplantation in systemic sclerosis is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Quantification and Characterization of Circulating Epithelial and Endothelial Cells in Gougerot-Sjögren Syndrome, Compared to Systemic Sclerosis [NA]
A completed clinical trial comparing circulating epithelial and endothelial cells in primary Sjögren's syndrome and diffuse systemic scleros…
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: Safety and Tolerability Study of AVID200 in Pts With Diffuse Cutaneous Systemic Sclerosis [Phase 1]
AVID200's Phase 1 safety and tolerability study in patients with diffuse cutaneous systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: Exercise With Scleroderma Functional Outcomes [NA]
A completed clinical trial evaluating the effects of an exercise program on functional outcomes in patients with systemic sclerosis (sclerod…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Brentuximab Vedotin for Systemic Sclerosis [Phase 1, Phase 2]
A clinical trial update reports completion of Phase 1/2 studies evaluating Brentuximab Vedotin for diffuse cutaneous systemic sclerosis (scl…
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CLINICAL_TRIALS trial_result · 2024-04-19Clinical Trial Update: A Study With TEPEZZA in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc) [Phase 1]
A Phase 1 study of teprotumumab (TEPEZZA) for diffuse cutaneous systemic sclerosis was terminated, and results were posted on 2024-04-19.
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CLINICAL_TRIALS trial_result · 2024-02-05Clinical Trial Update: Safety and Pharmacokinetics of IgPro20 and IgPro10 in Adults With Systemic Sclerosis (SSc) [Phase 2]
Phase 2 clinical trial evaluating safety and pharmacokinetics of IgPro20 and IgPro10 in adults with diffuse cutaneous systemic sclerosis has…
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CLINICAL_TRIALS trial_result · 2023-10-04Clinical Trial Update: Brentuximab Vedotin in Early Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 trial update for Brentuximab Vedotin in early diffuse cutaneous systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2023-08-30Clinical Trial Update: KD025 in Subjects With Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 clinical trial update for KD025 in diffuse cutaneous systemic sclerosis is terminated with results posted.
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CLINICAL_TRIALS trial_result · 2023-06-05Clinical Trial Update: Efficacy and Safety of Belumosudil in Subjects With Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 trial update on belumosudil for diffuse cutaneous systemic sclerosis; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2021-05-24Clinical Trial Update: Proof of Mechanism Study of GSK2330811 in Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 proof-of-mechanism study of GSK2330811 in diffuse cutaneous systemic sclerosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-03-29Clinical Trial Update: Trial to Evaluate Efficacy and Safety of Lenabasum in Diffuse Cutaneous Systemic Sclerosis [Phase 3]
Phase 3 trial evaluating lenabasum for diffuse cutaneous systemic sclerosis has been terminated.
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CLINICAL_TRIALS trial_result · 2020-08-12Clinical Trial Update: Atorvastatin for Microvascular Endothelial Function and Raynaud in Early Diffuse Scleroderma [Phase 2]
Phase 2 trial investigating atorvastatin for microvascular endothelial function and Raynaud phenomenon in early diffuse cutaneous systemic s…
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CLINICAL_TRIALS trial_result · 2019-06-18Clinical Trial Update: A Study of Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 clinical trial evaluating subcutaneous abatacept for diffuse cutaneous systemic sclerosis has completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-03-04Clinical Trial Update: Proof-of-concept Trial of IVA337 in Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 proof-of-concept trial of IVA337 in diffuse cutaneous systemic sclerosis (scleroderma) completed.
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CLINICAL_TRIALS trial_result · 2018-10-02Clinical Trial Update: Safety, Tolerability, Efficacy, and Pharmacokinetics of JBT-101 in Systemic Sclerosis [Phase 2]
Phase 2 trial of JBT-101 in diffuse cutaneous systemic sclerosis was terminated with posted results.
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: IVIG Treatment in Systemic Sclerosis [NA]
Clinical trial update on intravenous immunoglobulin (IVIG) treatment for systemic sclerosis, including the diffuse cutaneous form; the trial…
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CLINICAL_TRIALS trial_result · 2018-05-01Clinical Trial Update: IL1-TRAP, Rilonacept, in Systemic Sclerosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports on IL1-TRAP (rilonacept) for systemic sclerosis (scleroderma), with the study completed and result…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Treatment Outcome in Early Diffuse Cutaneous Systemic Sclerosis
Clinical trial update reporting treatment outcomes in early diffuse cutaneous systemic sclerosis.