Diffuse Astrocytoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma [NA]
Clinical trial evaluating hippocampal-avoidance using proton therapy in various low-grade gliomas; the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas [Phase 1, Phase 2]
Clinical trial update on a phase 1/2 study evaluating retifanlimab with or without difluoromethylornithine for progressive high-grade glioma…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Pediatric Long-Term Follow-up and Rollover Study [Phase 4]
Pediatric long-term follow-up and rollover study (Phase 4) sponsored by Novartis is active but not recruiting, tracking outcomes in children…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma [EARLY_Phase 1]
Early-phase study evaluating the use of 18F-FDOPA PET imaging to plan surgery and radiation therapy for adults with newly diagnosed malignan…
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma [Phase 2]
Phase 2 trial comparing proton beam therapy with intensity-modulated radiation therapy for preserving brain function in IDH-mutant grade II/…
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma [Phase 1]
Phase 1 study of CC-90010 assesses CNS penetration, pharmacokinetics, and pharmacodynamics in progressive/recurrent diffuse astrocytoma, ana…
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CLINICAL_TRIALS trial_result · 2020-12-10Clinical Trial Update: Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas [Phase 1, Phase 2]
Clinical trial update on proton beam radiation therapy for various adult brain tumors, spanning Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2020-11-04Clinical Trial Update: Vaccine for Patients With Newly Diagnosed or Recurrent Low-Grade Glioma [Phase 2]
Phase 2 clinical trial update for a vaccine in newly diagnosed or recurrent low-grade glioma, with completed status and results posted.
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CLINICAL_TRIALS trial_result · 2019-09-09Clinical Trial Update: Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas [Phase 1]
Phase 1 trial evaluating alisertib in combination with fractionated stereotactic radiosurgery for adults with recurrent high-grade gliomas h…
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CLINICAL_TRIALS trial_result · 2019-04-25Clinical Trial Update: Everolimus in Treating Patients With Recurrent Low-Grade Glioma [Phase 2]
Phase 2 clinical trial of everolimus in adults with recurrent low-grade glioma has completed; results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2017-03-27Clinical Trial Update: Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases [NA]
A clinical trial comparing gadobutrol to gadopentetate dimeglumine or gadobenate dimeglumine before DCE-MRI in patients with multiple sclero…
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CLINICAL_TRIALS trial_result · 2016-04-18Clinical Trial Update: Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma [Phase 1, Phase 2]
Clinical trial update for Temsirolimus and Perifosine in recurrent or progressive malignant glioma (Phase 1/2) with completed status and pos…
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CLINICAL_TRIALS trial_result · 2016-02-29Clinical Trial Update: Sunitinib in Treating Patients With Recurrent Malignant Gliomas [Phase 2]
Phase 2 trial evaluating sunitinib for adults with recurrent malignant gliomas has completed; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2015-06-15Clinical Trial Update: Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma [Phase 1, Phase 2]
This entry reports the completion and posted results of a Phase 1/2 trial evaluating erlotinib in combination with temsirolimus for recurren…
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CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: Natural History of Brain Function, Quality of Life, and Seizure Control in Patients With Brain Tumor Who Have Undergone Surgery
This completed clinical trial examined the natural history of brain function, quality of life, and seizure control in adults with brain tumo…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction [Phase 1]
Phase 1 clinical trial evaluating erlotinib in patients with solid tumors and liver or kidney dysfunction has been completed.
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CLINICAL_TRIALS research · 2013-01-16Clinical Trial Update: Use of EF5 to Measure the Oxygen Level in Tumor Cells of Patients Undergoing Surgery or Biopsy for Newly Diagnosed Supratentorial Malignant Glioma [NA]
A terminated clinical trial evaluated the use of EF5 to measure oxygen levels in tumor cells of patients with newly diagnosed supratentorial…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors [Phase 1]
This document is a terminated Phase 1 trial update evaluating PET imaging with 18F-EF5 to measure oxygenation in brain tumor cells of adults…