Diabetic Macular Edema
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Home- vs Hospital-based Care of Anti-VEGF Treatment for Diabetic Macular Edema: Non-inferiority RCT [NA]
A non-inferiority randomized trial is evaluating home-based versus hospital-based anti-VEGF treatment for diabetic macular edema and is curr…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: EC-104 Intravitreal Implant for the Treatment of Diabetic Macular Edema [Phase 1, Phase 2]
Clinical trial update for EC-104 intravitreal implant to treat Diabetic Macular Edema; a Phase 1/2 study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: A Study to Investigate RO7200220 as Monotherapy and in Combination With Ranibizumab in Participants With Diabetic and Uveitic Macular Edema [Phase 1]
A Phase 1 trial evaluating RO7200220 as monotherapy and in combination with ranibizumab in participants with diabetic macular edema and uvei…
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: A Study Intravitreal THN391 in Diabetic Macular Oedema Secondary to Non-Proliferative Diabetic Retinopathy. [Phase 1]
A Phase 1 intravitreal study of THN391 for diabetic macular edema due to non-proliferative diabetic retinopathy is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Describing Patient With DME, Their Patient Journey and Disease Progression
This document provides a clinical trial update describing a patient with diabetic macular edema, including their treatment journey and disea…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Micropulse for Suppression of Diabetic Macular Edema [NA]
The University of California, Davis completed a clinical trial evaluating micropulse laser treatment to suppress diabetic macular edema, wit…
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CLINICAL_TRIALS trial_result · 2024-11-27Clinical Trial Update: Ocular Safety and Usability Study for FYB203 PFS [Phase 4]
Phase 4 ocular safety and usability study of FYB203 PFS has completed, evaluating safety outcomes and usability in age-related macular degen…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Comparative Study Between IVI of Ranibizumab with and Without Prior ACP in Patients with DME Using OCT-A [Phase 4]
A Phase 4 trial evaluating intravitreal ranibizumab with versus without prior ACP in diabetic macular edema using OCT-A; the study has compl…
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CLINICAL_TRIALS research · 2024-11-26Clinical Trial Update: Aflibercept in Recurrent or Persistent CNV
This clinical trial update indicates recruitment for a study of aflibercept in recurrent or persistent choroidal neovascularization. The con…
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: Mean Visual Acuity Changes Following Five Injections of Aflibercept [NA]
This clinical trial reports mean visual acuity changes after five aflibercept injections in diabetic macular edema. The study is sponsored b…
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CLINICAL_TRIALS withdrawal · 2024-11-25Clinical Trial Update: An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting
A clinical trial investigating aflibercept 8 mg for neovascular age-related macular degeneration and diabetic macular edema in real-world se…
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Oxulumis® Suprachoroidal Microcatherization of Triesence® in Diabetic Macular Edema [Phase 2]
A Phase 2 trial evaluating suprachoroidal administration of Triesence for diabetic macular edema has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Participants With Diabetic Macular Edema [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics, and pharmacodynamics of GSK2798745 in participants with diabetic macular ed…
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: Safety and Effect of Intravitreal Injection of a Derivative of Nucleoside Reverse Transcriptase Inhibitor in Subjects with Diabetic Macular Edema [Phase 1]
Phase 1 trial evaluating safety and preliminary efficacy of intravitreal injection of a derivative of a nucleoside reverse transcriptase inh…
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: A Study to Evaluate ASP8232 in Reducing Central Retinal Thickness in Subjects With Diabetic Macular Edema (DME) [Phase 2]
Phase 2 clinical trial evaluating ASP8232 for reducing central retinal thickness in diabetic macular edema has completed.
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: A Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Participants With Diabetic Macular Edema [Phase 3]
This Clinical Trial Update reports the long-term safety and tolerability results from a Phase 3 study of Faricimab in participants with Diab…
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FDA approval · 2024-10-10FDA Approved: EYLEA HD — Supplemental Application (Regeneron Pharmaceuticals, Inc)
The FDA approved a supplemental application for EYLEA HD (aflibercept) from Regeneron, enabling use of the high-dose formulation for treatin…
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: The Use of ARA290 for the Treatment of Diabetic Macular Oedema [Phase 2]
Phase 2 trial of the drug ARA-290 for diabetic macular edema was terminated.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: To Compare Brolucizumab to Aflibercept in Chinese Patients With Visual Impairment Due to Diabetic Macular Edema [Phase 3]
Phase 3 trial comparing brolucizumab to aflibercept in Chinese patients with diabetic macular edema has completed and results have been post…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Efficacy and Safety of Intravitreal Injection of Bevacizumab with and Without Oral Curcumin [Phase 2, Phase 3]
A Phase 2/3 clinical trial is investigating intravitreal bevacizumab with and without oral curcumin for diabetic macular edema and macular e…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Evaluation of NeoRetina Artificial Intelligence Algorithm for the Screening of Diabetic Retinopathy at the CHUM [NA]
A CHUM-based study is evaluating the NeoRetina artificial intelligence algorithm for screening diabetic retinopathy, including diabetic macu…
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CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: Evaluation of Therapeutic Efficacy of Faricimab for Clinical AMD, DME, and RVO Patients [Phase 2, Phase 3]
Clinical trial update evaluating the efficacy of Faricimab for age-related macular degeneration, diabetic macular edema, and retinal vein oc…
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: A Trial to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME) [Phase 3]
Phase 3 trial comparing KSI-301 to Aflibercept in diabetic macular edema was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME) [Phase 3]
A Phase 3 study comparing KSI-301 with Aflibercept in diabetic macular edema was terminated, with results posted on 2024-08-22.
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: Discovering Early Biomarkers in Circulating Endothelial Cells for Diabetes Complications by Single Cell RNA Sequencing
A completed study from Aarhus University Hospital investigates early biomarkers in circulating endothelial cells for diabetes complications …