Diabetic Macular Edema
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: VEGFA-targeting Gene Therapy to Treat Retinal and Choroidal Neovascularization Diseases [EARLY_Phase 1]
An early-phase clinical trial from Shanghai BDgene is evaluating a VEGFA-targeting gene therapy for neovascular age-related macular degenera…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: A Study to Evaluate the Safety and Tolerability of EXN407 [Phase 1, Phase 2]
The study of EXN407 in diabetic macular edema completed Phase 1 and Phase 2 with results posted.
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CLINICAL_TRIALS research · 2025-05-09Clinical Trial Update: Medico Economic Evaluation of Fluocinolone Acetonide Implant Versus Dexametheasone Implant in Resistant Diabetic Macular Oedema [Phase 4]
Phase 4 clinical trial evaluating the economic comparison between fluocinolone acetonide intravitreal implant (Iluvien) and dexamethasone in…
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CLINICAL_TRIALS trial_result · 2025-05-04Clinical Trial Update: Targeted Laser in Diabetic Macular Edema [NA]
Completed clinical trial evaluating targeted laser therapy for diabetic macular edema and diabetic retinopathy.
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Safety, Tolerability and PK of Subcutaneous D-4517.2 in Subjects With Wet AMD or DME [Phase 2]
Phase 2 study update on the safety, tolerability, and pharmacokinetics of subcutaneous D-4517.2 in participants with neovascular age-related…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Is Community Based Monitoring of Diabetic Maculopathy and Pre-proliferative Diabetic Retinopathy Safe? [NA]
A clinical trial is assessing the safety of community-based monitoring for diabetic maculopathy and pre-proliferative diabetic retinopathy a…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: Phase 2 Trial of RGX-314 in Adults With Center Involved - Diabetic Macular Edema (CI - DME) [Phase 2]
A Phase 2 trial evaluating RGX-314 for center-involved diabetic macular edema is currently recruiting in adults.
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Impact of Intravitreal Faricimab on Renal Function in Diabetic Patients [NA]
Clinical trial update notes ongoing recruitment for a study evaluating the impact of intravitreal Faricimab on renal function in patients wi…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Long-Term Follow-up Study of ADVM-022 in DME (INFINITY-EXT)
This clinical trial update covers the long-term follow-up study of ADVM-022 in diabetic macular edema (INFINITY-EXT); the trial is currently…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Investigating the Metabolic and Lipidomic Profiles That Are Associated With Varying Grades of Diabetic Maculopathy and Retinopathy in South Wales
A clinical trial in South Wales is examining the metabolic and lipidomic profiles linked to different severities of diabetic retinopathy and…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Implementation of the Intravitreal Injection Administered by Nurses
A clinical trial update describes implementing intravitreal injections administered by nurses, potentially expanding access in studies for m…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Safety and Efficacy of IBE-814 Intravitreal (IVT) Implant - a Sustained, Low Dose Dexamethasone Therapy [Phase 2]
Phase 2 study assessing the safety and efficacy of the IBE-814 dexamethasone intravitreal implant for diabetic macular edema and macular ede…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: A 3-month Study to Assess the Safety of ONS-5010 in Subjects With Visual Impairment Due to Retinal Disorders [Phase 3]
A 3-month Phase 3 safety study of ONS-5010 in subjects with visual impairment due to retinal disorders has completed.
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Comparison of Intravitreal Bevacizumab Injection with Combination of Suprachoroidal Triamcinolone Acetonide Along with Intravitreal Bevacizumab Injection in the Treatment of Diabetic Macular Edema in Pseudophakic Patients [Phase 4]
A Phase 4 trial completed in pseudophakic patients with diabetic macular edema comparing intravitreal bevacizumab alone versus bevacizumab w…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Change in Ocular Perfusion After Intravitreal Anti-VEGF in Patients with Age-related Maculopathy or Diabetic Macula Edema
A completed clinical trial reports a change in ocular perfusion after intravitreal anti-VEGF therapy in patients with age-related macular de…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: Effectiveness of Intravitreal Injection of Aflibercept 8 mg in Resistant Diabetic Macular Edema, Retinal Vein Occlusion and Myopic Choroidal Neovascularisation Patients [EARLY_Phase 1]
Phase 1 trial evaluating intravitreal aflibercept 8 mg for resistant diabetic macular edema, retinal vein occlusion, and myopic choroidal ne…
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FDA approval · 2025-03-12FDA Approved: ILUVIEN — Supplemental Application (ANI Pharmaceuticals, Inc.)
FDA approved a supplemental application for ILUVIEN (fluocinolone acetonide intravitreal implant) by ANI Pharmaceuticals, Inc.
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Effect of AIV007 by Periocular Administration in Subjects with Macular Edema Secondary to Neovascular Age-related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) [Phase 1]
Phase 1 clinical trial update for AIV007 delivered periocularly in patients with macular edema due to Neovascular Age-Related Macular Degene…
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CLINICAL_TRIALS trial_result · 2025-03-04Clinical Trial Update: Study of EYP-1901 in Patients With Diabetic Macular Edema (DME) [Phase 2]
Phase 2 study of EYP-1901 for diabetic macular edema has completed.
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Early Combined Use of Dexamethasone Intravitreal Implant and Anti-VEGF in the Treatment of DME. [NA]
Update on a trial investigating early combined dexamethasone intravitreal implant with anti-VEGF therapy for diabetic macular edema; current…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Early Changes in OCT Biomarkers After the First Intravitreal Anti-VEGF Injection in Treatment-naïve DME
This clinical trial update describes a study evaluating early OCT biomarker changes after the first intravitreal anti-VEGF injection in trea…
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CLINICAL_TRIALS other · 2025-02-21Clinical Trial Update: A Phase 2 Study to Evaluate the Efficacy and Safety of ENN0403 in Subjects with DME [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of ENN0403 for diabetic macular edema is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Study of JMKX003948 Ophthalmic Suspension in Healthy Participants [Phase 1]
Phase 1 clinical trial update for JMKX003948 Ophthalmic Suspension in healthy participants; study status is not yet recruiting.
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: Predicting Diabetic Retinopathy From Risk Factor Data and Digital Retinal Images
Clinical trial update describing a study that aims to predict diabetic retinopathy using risk factor data and digital retinal images; the tr…
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: Aqueous Biomarker Levels in Diabetic Retinopathy and Diabetic Macular Edema
A clinical trial examining aqueous biomarker levels in Diabetic Retinopathy and Diabetic Macular Edema was terminated. No results are report…