Diabetic Kidney Disease
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CLINICAL_TRIALS trial_result · 2026-08-24Clinical Trial Results: Renal Hemodynamics, Energetics and Insulin Resistance: A Follow-up Study
A completed clinical trial investigating renal hemodynamics, energetics, and insulin resistance in subjects with type 2 diabetes, with resul…
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CLINICAL_TRIALS trial_result · 2026-07-28Clinical Trial Results: Uric Acid Lowering Trial in Youth Onset T2D [Phase 2]
Phase 2 trial results for an uric acid-lowering therapy in youth-onset type 2 diabetes; study is completed with results posted.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Mechanisms of Diabetic Kidney Disease in American Indians
A clinical trial on mechanisms of diabetic kidney disease in American Indians funded by NIDDK has been suspended.
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease [Phase 2]
Regeneron is sponsoring a Phase 2 clinical trial to assess ANGPTL3 inhibition in adults with diabetic kidney disease, and the study is curre…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study [Phase 4]
This Phase 4 DESIGN study reports results on how dietary sodium intake modulates ertugliflozin-induced changes in GFR, renal oxygenation, an…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Family Investigation of Nephropathy and Diabetes (F.I.N.D.)
The Family Investigation of Nephropathy and Diabetes (F.I.N.D.) trial registry entry describes an NIDDK-supported study on diabetic nephropa…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Pentoxifylline in Diabetic Kidney Disease [Phase 4]
This update notes an ongoing Phase 4 clinical trial of pentoxifylline for diabetic kidney disease, sponsored by the VA Office of Research an…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Spironolactone Alternate Dosing vs Finerenone in Elevated Potassium - K Safety Study [Phase 4]
A Phase 4 trial comparing alternate dosing of spironolactone versus finerenone to evaluate safety in patients with elevated potassium relate…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Multimodal Magnetic Resonance Imaging in Evaluation of Diabetic Kidney Disease
A clinical trial evaluating multimodal magnetic resonance imaging in Diabetic Kidney Disease is currently recruiting at Shengjing Hospital.
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: The Evaluation of the Drug R3R01 for the Excretion of Protein in the Urine in Patients With Diabetic Kidney Disease. [Phase 2]
A Phase 2 clinical trial is evaluating R3R01 for reducing proteinuria in patients with diabetic kidney disease and is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Safety and Efficacy of Mesenchymal Stromal Cells (Amimestrocel ) in Diabetic Kidney Disease [Phase 2]
Phase 2 clinical trial evaluating safety and efficacy of amimestrocel, a mesenchymal stromal cell therapy, in diabetic kidney disease; curre…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Improving Kidney Care in Type 2 Diabetes: A Study of Pharmacist Prescribing Versus Usual Care [NA]
A recruiting clinical trial comparing pharmacist prescribing against usual care for kidney care in adults with Type 2 diabetes, including di…
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CLINICAL_TRIALS other · 2026-03-16Clinical Trial Update: Evaluation of MTX-439 in Healthy Adults and Adults With Diabetic Kidney Disease [Phase 1]
Clinical Trial Update notes that MTX-439 is in a Phase 1 trial in healthy adults and adults with diabetic kidney disease and is currently no…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Investigation on the Impact of Finerenone on Myocardial Remodeling in Patients With Diabetic Kidney Disease and Heart Failure [Phase 4]
Phase 4 clinical trial investigating the effect of finerenone on myocardial remodeling in patients with diabetic kidney disease and heart fa…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Goal-Directed Therapy to Reduce Kidney and Cardiovascular Risk in Diabetic Kidney Disease (GOLD-STANDARD) [NA]
This clinical trial update announces the GOLD-STANDARD study evaluating goal-directed therapy to reduce kidney and cardiovascular risk in di…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Immune System in Diabetic Kidney Disease
Enrollment by invitation is underway for a clinical study investigating the immune system in diabetic kidney disease, sponsored by Universit…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Treatment Optimization for Patients With Type 2 Diabetes Using Empagliflozin and Finerenone in a Remote Clinical Trial [Phase 4]
A Phase 4 clinical trial update reports on optimizing therapy for type 2 diabetes patients with kidney involvement using empagliflozin and f…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Exercise Study Testing Enhanced Energetics of Mitochondria Video Integrated Delivery of Activity Training in CKD [NA]
A clinical trial evaluating an exercise intervention aimed at improving mitochondrial energetics in chronic kidney disease has completed.
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Formoterol in Diabetes [Phase 2]
Phase 2 clinical trial investigating formoterol for diabetic nephropathy and diabetic kidney disease is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: Study of Roxadustat's Effect on Anemia in Patients With Diabetic Kidney Disease [Phase 4]
A Phase 4 clinical trial evaluating Roxadustat for anemia in patients with diabetic kidney disease has completed.
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Impact of Diabetes-Related Metabolic Derangements on Clinical Outcomes in Hospitalized Patients With Chronic Kidney Disease
A clinical trial is investigating how diabetes-related metabolic derangements affect outcomes in hospitalized patients with chronic kidney d…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Gut Microbiota and Serum Metabolites as Predictors of Glycemic Variability and Outcomes in Diabetic Kidney Disease
This clinical trial investigates whether gut microbiota composition and serum metabolites can predict glycemic variability and outcomes in p…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Rubix LS Diabetic Kidney Disease (DKD) Registry Study
This entry provides an update on the Rubix LS Diabetic Kidney Disease (DKD) registry study, a clinical trial registry investigating diabetic…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: "Residual Kidney Function and Oxidative Stress in Incremental vs Standard Peritoneal Dialysis (2 Mexican Centers)" [NA]
ClinicalTrials.gov update notes an active-not-recruiting study comparing incremental versus standard peritoneal dialysis, focusing on residu…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Finerenone for Cardiorenal Protection in Diabetic CKD: Impact on Renal Function Decline and Heart Failure [NA]
This clinical trial update describes evaluating finerenone for cardiorenal protection in diabetic kidney disease and heart failure, with the…