Detrusor Overactivity
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Does Position Influence the Diagnosis of Detrusor Overactivity in a Neurological Population [NA]
Clinical trial evaluating whether patient position influences the diagnosis of detrusor overactivity in individuals with neurological disord…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Children Toxine Botulinum Detrusor Injection in Neurogenic Vesical Hyperactivity Syndrom: Non Inferiority Multicenter Controlled Therapeutic Study Between Two Reported Weight's Doses [Phase 3]
Phase 3 non-inferiority multicenter trial comparing two weight-based doses of botulinum toxin injected into the detrusor for pediatric neuro…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Effects of Sacral and Tibial Stimulation on Bladder Function in Subacute Suprasacral Spinal Cord Injury [NA]
A clinical trial is evaluating sacral and tibial nerve stimulation to improve bladder function in subacute suprasacral spinal cord injury; c…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Platelet-Rich Plasma Versus Botulinum Toxin for Refractory Overactive Bladder: A Randomized Trial [NA]
This document describes an ongoing randomized trial sponsored by Benha University comparing platelet-rich plasma injections to botulinum tox…
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: Central Nervous System Changes Following OnabotulinumtoxinA Injection in the Bladder
A completed clinical trial evaluating central nervous system changes after intravesical OnabotulinumtoxinA injections for bladder symptoms, …
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CLINICAL_TRIALS trial_result · 2020-05-29Clinical Trial Update: Oral vs Intravesical Analgesia for Office Bladder Botox Injections [Phase 4]
A Phase 4 trial comparing oral versus intravesical analgesia for office-based bladder Botox injections in overactive bladder conditions is u…
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: Efficacy Study of Pudendal Neuromodulation for the Treatment of Neurogenic Overactive Bladder [NA]
This clinical trial update reports that a study evaluating pudendal neuromodulation for neurogenic overactive bladder and urinary incontinen…
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CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: Injections of Botulinum Toxin A in Treatment of Patients With Detrusor Overactivity and Impaired Contractility [Phase 2]
Phase 2 clinical trial evaluating injections of Botulinum toxin type A for detrusor overactivity with impaired contractility; study complete…
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CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: UNGF Assessment in Patients With Detrusor Overactivity Undergoing Sacral Neuromodulation
The clinical trial evaluating UNGF assessment in detrusor overactivity patients undergoing sacral neuromodulation has completed. It was spon…
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FDA approval · 2014-07-18FDA Approved: OXYTROL — Supplemental Application (Allergan, Inc.)
FDA approved a supplemental application for OXYTROL (oxybutynin) from Allergan, Inc.
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CLINICAL_TRIALS trial_result · 2014-07-11Clinical Trial Update: Over Active Bladder Instillation Study - Botox [Phase 3]
Phase 3 study of intravesical Botox for overactive bladder was terminated with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-04-21Clinical Trial Update: Botulin-A Toxin Instillations and Overactive Bladder [Phase 1, Phase 2]
A Mayo Clinic-sponsored Phase 1/2 trial evaluated botulinum toxin type A instillations for overactive bladder/detrusor overactivity; results…
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CLINICAL_TRIALS trial_result · 2014-04-07Clinical Trial Update: Study of 2 Doses of Solifenacin Succinate in Female Subjects With Overactive Bladder. [Phase 4]
A Phase 4 clinical trial update evaluating two doses of solifenacin succinate in women with overactive bladder has completed and posted resu…
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CLINICAL_TRIALS trial_result · 2013-07-31Clinical Trial Update: Extended-Release Oxybutynin for the Treatment of Neurogenic Detrusor Overactivity [Phase 4]
This Phase 4 trial of extended-release oxybutynin for neurogenic detrusor overactivity was terminated. Results were posted in July 2013.
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CLINICAL_TRIALS trial_result · 2012-09-21Clinical Trial Update: A Parallel Group Study to Compare Sativex® With Placebo in the Treatment of Detrusor Overactivity in Patients With Multiple Sclerosis [Phase 3]
A Phase 3 parallel-group study compared Sativex with placebo for detrusor overactivity in patients with multiple sclerosis; the trial is com…
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FDA approval · 2011-11-02FDA Approved: OXYBUTYNIN CHLORIDE — Supplemental Application (Lannett Company, Inc.)
FDA approved a supplemental application for oxybutynin chloride from Lannett Company, expanding the availability of a generic formulation.
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CLINICAL_TRIALS trial_result · 2011-01-11Clinical Trial Update: Refractory Urge Incontinence and Botox Injections [Phase 3]
A Phase 3 trial evaluating botulinum toxin injections for refractory urge incontinence due to detrusor overactivity was terminated.
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CLINICAL_TRIALS trial_result · 2009-12-24Clinical Trial Update: A Study To Assess If 10 mg Vardenafil (BAY38-9456) Taken Twice Daily For 6 Weeks Has An Effect On Bladder Function [Phase 2]
A Phase 2 study tested whether 10 mg vardenafil taken twice daily for six weeks affects bladder function in participants with overactive bla…
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CLINICAL_TRIALS trial_result · 2009-10-28Clinical Trial Update: Ultrasonographic Bladder Wall Thickness and Different Forms of Detrusor Overactivity
This completed clinical trial from Università degli Studi dell'Insubria examined ultrasonographic bladder wall thickness across different fo…
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CLINICAL_TRIALS research · 2009-01-15Clinical Trial Update: Botulinum A Toxin in Patients With Parkinson's Disease [Phase 4]
Phase 4 clinical trial update evaluating botulinum toxin type A in patients with Parkinson's disease and related conditions; trial status is…