Desmoplastic Small Round Cell Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR) [Phase 1]
Phase 1 clinical trial update for a B7-H3–targeted autologous CAR-T cell therapy (3CAR) in pediatric solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Clinical Study in Adult and Young Adult Patients With Advanced Desmoplastic Small Round Cell Tumor (DSRCT) ISG-TULIPS [Phase 2]
Phase 2 clinical trial update for ISG-TULIPS evaluating treatment in adults and young adults with advanced Desmoplastic small round cell tum…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Lurbinectedin in FET-Fused Tumors [Phase 1, Phase 2]
Phase 1/2 trial evaluates Lurbinectedin in FET-fused tumors such as Ewing sarcoma and desmoplastic small round cell tumor. Recruitment is on…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating alpha/beta T and B cell depletion with zoledronic acid for solid tumors; recruitment is ongoing.
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Prospective Identification of Predictive Biomarkers of Trabectedin Efficacy in Non-L Soft-tissue Sarcoma Patients [NA]
Trial update reporting prospective identification of predictive biomarkers for trabectedin efficacy across non-liposarcoma soft tissue sarco…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the safety and potential efficacy of PEEL-224 in combination with vincristine and temozolomide in a…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group [NA]
An ongoing clinical trial under the MIRAS project aims to perform multimodal immune characterization of rare soft tissue sarcomas and relate…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Registry to Collect Health Information About Desmoplastic Small Round Cell Tumor
A registry trial at Memorial Sloan Kettering Cancer Center will collect health information from people with Desmoplastic Small Round Cell Tu…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS) [Phase 2]
Phase 2 trial evaluating an immuno-oncology combination as first-line treatment for soft tissue sarcomas; currently recruiting.
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
A Phase 1 trial update for EGFR806 CAR T cell immunotherapy in pediatric and young adult patients with recurrent/refractory solid tumors; th…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Irinotecan, Temozolomide and Bevacizumab in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Newly Diagnosed Patients With Desmoplastic Small Round Cell Tumor [EARLY_Phase 1]
This early-phase 1 clinical trial update describes a combination of irinotecan, temozolomide, and bevacizumab with high-dose alkylator chemo…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: A Study of LY2880070 and Gemcitabine in People With Ewing Sarcoma,Ewing-Like Sarcoma, and Desmoplastic Small Round Cell Tumor [Phase 2]
Phase 2 study of LY-2880070 in combination with gemcitabine for Ewing sarcoma, Ewing-like sarcoma, and desmoplastic small round cell tumor h…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Desmoplastic Small Round Cell Tumor [Phase 1, Phase 2]
A clinical trial update on ramucirumab (LY3009806) being studied in children and young adults with desmoplastic small round cell tumor in Ph…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: A Study of the Drug I131-Omburtamab in People With Desmoplastic Small Round Cell Tumors and Other Solid Tumors in the Peritoneum [Phase 2]
Phase 2 clinical trial update for I-131 Omburtamab in Desmoplastic Small Round Cell Tumor and other peritoneal cancers; the study is current…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults [Phase 2]
A Phase 2 trial evaluating donor stem cell transplant after chemotherapy for recurrent or refractory high-risk solid tumors in pediatric and…
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CLINICAL_TRIALS withdrawal · 2025-05-18Clinical Trial Update: Study of High Dose Intravenous (IV) Ascorbic Acid in Measurable Solid Tumor Disease [Phase 2]
A Phase 2 trial evaluating high-dose intravenous ascorbic acid in measurable solid tumors has been withdrawn, sponsored by Situs Cancer Rese…
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CLINICAL_TRIALS research · 2025-02-26Clinical Trial Update: Safety and Efficacy of CAR-T Cell Therapy for Relapsed/refractory Neuroblastoma and Desmoplastic Small Round Cell Tumors: a Single-arm, Open-label Trial. [Phase 1, Phase 2]
This document outlines an ongoing single-arm, open-label Phase 1/2 trial assessing the safety and efficacy of CAR-T cell therapy in relapsed…
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: A Study of the Drugs Prexasertib, Irinotecan, and Temozolomide in People With Desmoplastic Small Round Cell Tumor and Rhabdomyosarcoma [Phase 1, Phase 2]
A phase 1/2 trial evaluating the combination of prexasertib, irinotecan, and temozolomide in Desmoplastic Small Round Cell Tumor and rhabdom…
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients [EARLY_Phase 1]
Early-phase 1 clinical trial evaluating heated intraperitoneal chemotherapy with doxorubicin and cisplatin for pediatric abdominal/pelvic tu…
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: Pasireotide as Maintenance Treatment in Synovial Sarcoma and Desmoplastic Small Round Cell Tumor [Phase 2]
A Phase 2 clinical trial evaluating pasireotide as maintenance therapy in Desmoplastic Small Round Cell Tumor and Synovial Sarcoma is curren…
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: A Rollover Protocol to Allow for Continued Access to the LSD1 Inhibitor Seclidemstat (SP-2577) [Phase 1, Phase 2]
A rollover protocol update is described to allow continued access to the LSD1 inhibitor seclidemstat (SP-2577) in ongoing Phase 1/Phase 2 tr…
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CLINICAL_TRIALS trial_result · 2022-06-07Clinical Trial Update: Trial of Nab-paclitaxel in Patients With Desmoid Tumors and Multiply Relapsed/Refractory Desmoplastic Small Round Cell Tumors and Ewing Sarcoma [Phase 2]
Phase 2 trial evaluating nab-paclitaxel in desmoid tumors, desmoplastic small round cell tumors, and Ewing sarcoma; study status is complete…
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CLINICAL_TRIALS trial_result · 2019-10-01Clinical Trial Update: Pilot Study of Hyperthermic Peritoneal Perfusion (HIPEC) for Adolescent and Young Adults With Desmoplastic Small Round Cell Tumor [Phase 2]
Phase 2 pilot trial evaluating hyperthermic intraperitoneal perfusion (HIPEC) for adolescents and young adults with desmoplastic small round…
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinoma [Phase 2]
Phase II trial of nivolumab plus ipilimumab in non-resectable soft tissue and bone sarcomas, with exploration across several sarcoma subtype…
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CLINICAL_TRIALS research · 2017-08-22Clinical Trial Update: French National Registry of Rare Peritoneal Surface Malignancies
An update on the French National Registry of Rare Peritoneal Surface Malignancies (NCT02834169) detailing conditions affecting peritoneal su…