Desmoid Tumor
📧 Sign up to get email alerts when something new happens for Desmoid Tumor.
Sign up freeTop drugs studied for this disease
-
EMA approval · 2026-07-20EMA Authorised: Ogsiveo (nirogacestat hydrobromide) — Merck Europe B.V.
Marketing authorization has been granted for Ogsiveo (nirogacestat hydrobromide) by EMA for desmoid tumors.
-
CLINICAL_TRIALS trial_result · 2026-06-08Clinical Trial Update: A Study of AL102 in Patients With Progressing Desmoid Tumors [Phase 2, Phase 3]
Clinical trial update for AL102 in progressing desmoid tumors, currently active/not recruiting across Phase 2 and Phase 3.
-
CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: FOG-001 in Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
FOG-001 is being studied in a Phase 1/2 trial across multiple locally advanced or metastatic solid tumors and is currently recruiting; indic…
-
CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study in Adults With Desmoid Tumors [Phase 2]
Phase 2 clinical trial update for adults with desmoid tumors; the study is not yet recruiting.
-
CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: PRISM for Depression and Anxiety in Young Adults With Cancer [NA]
PRISM is a trial evaluating depression and anxiety in young adults with cancer; the study has completed.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by Surgery [Phase 2]
A Phase 2 clinical trial evaluating Nirogacestat for desmoid tumors that are unresectable or recurrent, currently listed as active not recru…
-
CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Evaluation of the Response and Non-response of Nirogacestat in Desmoid Tumors- Clinical Study [Phase 2]
Phase 2 clinical trial update evaluating the response and non-response to nirogacestat in desmoid tumors; study is currently recruiting.
-
CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Individual Patient Compassionate Use of Nirogacestat
The document reports that nirogacestat is available for individual patient compassionate use in Desmoid Tumor and NOTCH gene mutation–positi…
-
FDA approval · 2026-03-10FDA Approved: OGSIVEO — Supplemental Application (SpringWorks Therapeutics, Inc.)
The FDA approved a supplemental application for OGSIVEO (nirogacestat) from SpringWorks Therapeutics.
-
CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: Evaluation of the Cryodestruction of Non Abdominopelvic Desmoid Tumors in Patients Progressing Despite Medical Treatment [NA]
A completed clinical trial evaluated cryodestruction for desmoid tumors in patients not responding to medical therapy.
-
CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Cryoablation Versus Medical Therapy in Desmoid Tumors Progressing After Watchful Waiting [NA]
A clinical trial comparing cryoablation to medical therapy for desmoid tumors that progressed after watchful waiting is currently recruiting…
-
CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Study of Cryoablation and Nirogacestat for Desmoid Tumor [Phase 2]
A Phase 2 clinical trial evaluating cryoablation in combination with nirogacestat for desmoid tumors is currently recruiting.
-
CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Burden of Disease and Living Situation in Desmoid Patients
This clinical trial update examines the burden of disease and living situation in desmoid tumor patients; the study is completed.
-
CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Cryotherapy in the Treatment of Desmoid Tumors [NA]
A clinical trial update describing cryotherapy for desmoid tumors; the study is currently Recruiting.
-
CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers [Phase 1, Phase 2]
Phase 1/2 trial update evaluating nivolumab plus ABI-009 (nab-rapamycin) in patients with advanced sarcoma and selected cancers, with result…
-
CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: Radiomics Compared With Conventional Response Criteria for Predicting Progression of Desmoid Tumor After Cryoablation
This clinical trial evaluates whether radiomics features from imaging can predict progression of desmoid tumors after cryoablation, compared…
-
CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors [Phase 1]
Phase 1 trial completion evaluating MR-guided High Intensity Focused Ultrasound (HIFU) for relapsed or refractory pediatric solid tumors, in…
-
CLINICAL_TRIALS withdrawal · 2024-12-09Clinical Trial Update: Vactosertib and Imatinib Combination in Patients with Advanced Desmoid Tumor/aggressive Fibromatosis (DT/AF) [Phase 2]
A Phase 2 trial evaluating the combination of Vactosertib and Imatinib for advanced Desmoid Tumor / Aggressive Fibromatosis has been withdra…
-
CLINICAL_TRIALS trial_result · 2024-05-13Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor [Phase 1, Phase 2]
This document reports a completed Phase 1/2 clinical trial evaluating the safety and efficacy of Vactosertib in combination with Imatinib in…
-
FDA approval · 2023-11-27FDA Approved: OGSIVEO — Original Application (SpringWorks Therapeutics, Inc.)
FDA approved OGSIVEO (nirogacestat) through an original NDA submitted by SpringWorks Therapeutics, Inc. for the treatment of desmoid tumors.
-
CLINICAL_TRIALS trial_result · 2023-10-05Clinical Trial Update: Imatinib in Patients With Desmoid Tumor and Chondrosarcoma [Phase 2]
Phase 2 clinical trial update for imatinib in patients with advanced desmoid tumor and advanced chondrosarcoma has completed.
-
CLINICAL_TRIALS trial_result · 2023-06-26Clinical Trial Update: A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis [Phase 1, Phase 2]
Pilot study evaluating sirolimus (mTOR inhibitor) in children and young adults with desmoid-type fibromatosis completed; results posted.
-
CLINICAL_TRIALS trial_result · 2022-09-30Clinical Trial Update: A Randomized, Double-blind,Phase Ⅲ Study of Liposome Doxorubicin in Desmoid Tumor [Phase 3]
A Phase 3 randomized, double-blind trial evaluating liposome doxorubicin in desmoid tumor is ongoing; no results reported yet.
-
CLINICAL_TRIALS trial_result · 2022-06-07Clinical Trial Update: Trial of Nab-paclitaxel in Patients With Desmoid Tumors and Multiply Relapsed/Refractory Desmoplastic Small Round Cell Tumors and Ewing Sarcoma [Phase 2]
Phase 2 trial evaluating nab-paclitaxel in desmoid tumors, desmoplastic small round cell tumors, and Ewing sarcoma; study status is complete…
-
CLINICAL_TRIALS trial_result · 2022-03-25Clinical Trial Update: Doxorubicin Eluting Intra-arterial Embolization for Aggressive Desmoid Fibromatosis [Phase 2]
Phase 2 trial evaluating doxorubicin-eluting intra-arterial embolization for aggressive desmoid fibromatosis has completed.