Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2017-08-03Clinical Trial Update: Relative Bioavailability and Food Effect Study for GSK163090 in Healthy Male and Female Volunteers [Phase 1]
Phase 1 relative bioavailability and food-effect study of GSK163090 in healthy volunteers to characterize pharmacokinetics and potential foo…
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: Food and Relative Bioavailability Study [Phase 1]
Phase 1 study update on food effect and relative bioavailability sponsored by GlaxoSmithKline for a depressive disorder indication.
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: A Study To Investigate Effects Of GSK561679 On Brain Activation During Emotional Processing In Healthy Volunteers [Phase 1]
This Phase 1 study investigated the effects of GSK561679 on brain activation during emotional processing in healthy volunteers. The trial st…
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CLINICAL_TRIALS trial_result · 2017-07-07Clinical Trial Update: Emotional Processing in Healthy Volunteers in the Presence of an Investigational Anxiolytic [Phase 1]
A Phase 1 study by GlaxoSmithKline evaluating emotional processing in healthy volunteers in the presence of an investigational anxiolytic; t…
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: An Open Label Positron Emission Tomography Study in Healthy Male Subjects to Investigate Brain DAT and SERT Occupancy,Pharmacokinetics and Safety of Single Oral Doses of GSK1360707, Using 11C- PE2I and 11C-DASB as PET Ligands [Phase 1]
Phase 1 open-label PET study in healthy male subjects to evaluate brain DAT and SERT occupancy, pharmacokinetics, and safety after single or…
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: The Impact of Giving a Massage [EARLY_Phase 1]
This early Phase 1 trial evaluated the impact of giving a massage on mental-state measures related to depression, anxiety, or stress; the st…
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Bupropion and Specific Cardiovascular Malformations
A completed clinical trial update on bupropion exposure during pregnancy and its possible link to congenital cardiovascular malformations.
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CLINICAL_TRIALS trial_result · 2017-05-25Clinical Trial Update: Training Protocol 'Drop it'. The Impact of a Training Protocol Focused on Coping With Negative Repetitive Thinking on Cognitive and Behavioural Functioning of People Suffering From GAD or Minor or Moderate Depressive Disorder or Depressive Disorder in Remission [NA]
This clinical trial update reports the completion of a study evaluating a training protocol to cope with negative repetitive thinking in peo…
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CLINICAL_TRIALS research · 2017-05-11Clinical Trial Update: The Impact of Lifestyle on Mental Health Among Young Men in the Gilgel Gibe Field Research Center, Ethiopia: Pilot Study
A completed pilot study from Ethiopia examining how lifestyle factors affect mental health, focusing on common mental disorders and psychoti…
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CLINICAL_TRIALS trial_result · 2017-05-05Clinical Trial Update: Evaluation of a Health Plan Initiative to Mitigate Chronic Opioid Therapy Risks
A completed clinical trial evaluated a health plan–level initiative to mitigate risks from chronic opioid therapy, with results posted in 20…
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CLINICAL_TRIALS research · 2017-04-26Clinical Trial Update: A Clinical Evaluation of Subcallosal Cingulate Gyrus Deep Brain Stimulation for Treatment-Resistant Depression [NA]
An update on a clinical evaluation of Subcallosal Cingulate Gyrus Deep Brain Stimulation for treatment-resistant depression, sponsored by Ab…
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CLINICAL_TRIALS withdrawal · 2017-04-04Clinical Trial Update: Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions
This clinical trial update notes that the study evaluating quality of life in Freeman-Sheldon syndrome and related conditions has been termi…
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CLINICAL_TRIALS trial_result · 2017-03-17Clinical Trial Update: Pharmacological Intervention in Depression After Traumatic Brain Injury [Phase 4]
A Phase 4 clinical trial evaluating a pharmacological intervention for depression following traumatic brain injury has completed.
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Spot Depression Study
The update notes the completion of the Spot Depression Study (NCT02804867) conducted by the University of Cambridge, investigating treatment…
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CLINICAL_TRIALS research · 2016-12-22Clinical Trial Update: Interpersonal Counseling (IPC) for Treatment of Depression in Adolescents [NA]
This entry reports an update on a clinical trial evaluating interpersonal counseling (IPC) for treating depressive disorder in adolescents, …
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CLINICAL_TRIALS trial_result · 2016-09-15Clinical Trial Update: PET (Positron Emission Tomography)/Public Speaking Study With A Combination Of 2 Medications In Social Anxiety Patients [Phase 2]
Phase 2 PET/public speaking trial using a two-drug combination in social anxiety disorder has completed; results are not detailed in the pro…
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CLINICAL_TRIALS research · 2016-08-23Clinical Trial Update: The Clinical Research on the Relationship Between Depression and Gut Microbiota in TBI Patients
Clinical trial update on the relationship between depression and gut microbiota in patients with traumatic brain injury. The study focuses o…
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CLINICAL_TRIALS trial_result · 2016-08-16Clinical Trial Update: Developing and Testing of Culturally Adapted Cognitive Behavior Therapy (CaCBT) for Pashto Speaking Pakistanis and Afghans [NA]
A completed clinical trial evaluating culturally adapted cognitive-behavioral therapy for Pashto-speaking Pakistanis and Afghans with depres…
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CLINICAL_TRIALS trial_result · 2016-06-10Clinical Trial Update: Research Evaluating the Value of Augmenting Medication With Psychotherapy [Phase 4]
Phase 4 trial evaluating whether augmenting medication with psychotherapy improves outcomes in depression and depressive disorders. Results …
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CLINICAL_TRIALS trial_result · 2016-05-10Clinical Trial Update: Treatment of Depressive Symptoms in Breast Cancer Patients: Comparison of Cognitive Therapy and Bright Light Therapy [NA]
This clinical trial compared cognitive therapy and bright light therapy for depressive symptoms in breast cancer patients. The study has com…
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CLINICAL_TRIALS trial_result · 2016-04-21Clinical Trial Update: Comorbidities and Virologic Outcome Among Patients on Anti-retroviral Therapy in Rural Lesotho
This completed trial from rural Lesotho studied how comorbidities such as metabolic syndrome, depression, alcoholism, and hepatitis affect v…
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CLINICAL_TRIALS trial_result · 2016-04-14Clinical Trial Update: Correlating Real and Virtual World Behavioral Fluctuations in Adolescence
A completed clinical trial update examining associations between real-world and virtual-world behaviors in adolescents, focusing on attentio…
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CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: Buprenorphine for Treatment Resistant Depression [Phase 3]
Phase 3 trial evaluating buprenorphine for treatment-resistant depression has completed. Results were posted in March 2016.
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CLINICAL_TRIALS trial_result · 2016-03-11Clinical Trial Update: Health Care Management for the Elderly in Community Through Screening [NA]
This clinical trial update notes completion of a study on elderly community health management through screening, focusing on major depressiv…
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CLINICAL_TRIALS trial_result · 2015-11-26Clinical Trial Update: Study of the Safety and Efficacy of Fixed Dose OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Pyxis Trial) [Phase 3]
OPC-34712 was studied as adjunctive therapy in adults with major depressive disorder in a Phase 3 trial. The study is completed and results …