Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: TAK-653 Escalating Single and Multiple Dose Study in Healthy Participants [Phase 1]
Phase 1 trial update for TAK-653 in healthy participants completed, with results posted.
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CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: Acute Aerobic Exercise and Neuroplasticity in Depression [NA]
Completed clinical trial evaluating whether acute aerobic exercise affects neuroplasticity in individuals with depression.
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CLINICAL_TRIALS trial_result · 2018-10-29Clinical Trial Update: A Multicenter, Relapse Prevention Study With Levomilnacipran Extended Release (ER) in Participants With Major Depressive Disorder [Phase 4]
Phase 4 clinical trial update on relapse prevention with levomilnacipran ER in adults with major depressive disorder; results posted after c…
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CLINICAL_TRIALS trial_result · 2018-10-19Clinical Trial Update: A Study to Evaluate the Effect of Activated Charcoal on the Absorption of LY2216684 in Healthy Subjects [Phase 1]
Phase 1 study assessing the effect of activated charcoal on absorption of LY2216684 in healthy subjects completed; results posted.
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CLINICAL_TRIALS trial_result · 2018-09-17Clinical Trial Update: Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial) [Phase 3]
Phase 3 trial update on the safety and tolerability of oral OPC-34712 as an adjunctive therapy for adults with major depressive disorder.
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CLINICAL_TRIALS trial_result · 2018-08-21Clinical Trial Update: Study of the Safety and Efficacy of Fixed-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder With and Without Anxious Distress [Phase 3]
Phase 3 study evaluating fixed-dose brexpiprazole as adjunctive therapy in adults with major depressive disorder with and without anxious di…
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: Repeat Dose Study of Controlled-Release Paroxetine Tablets and Immediate-Release Paroxetine Tablets in Healthy Japanese Male Subjects [Phase 1]
Phase 1 repeat-dose study evaluating safety and pharmacokinetics of controlled-release and immediate-release paroxetine tablets in healthy J…
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: Single Dose Study of Controlled-Release Paroxetine Tablets in Healthy Japanese Male Subjects [Phase 1]
Phase 1 single-dose pharmacokinetic study of controlled-release paroxetine tablets in healthy Japanese male subjects has completed.
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CLINICAL_TRIALS trial_result · 2018-06-14Clinical Trial Update: Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders [Phase 1]
A Phase 1 outpatient trial for adolescents with comorbid substance use and internalizing disorders has completed.
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CLINICAL_TRIALS trial_result · 2018-06-11Clinical Trial Update: Effectiveness of Non-medical Health Worker (NMHW) Led Counseling on Common Mental Disorders in Rural Mid-western Nepal [NA]
A completed clinical trial evaluated the effectiveness of non-medical health worker–led counseling for common mental disorders in rural Mid-…
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: Family Based Treatment of Depressed Adolescents (AHUS) [NA]
The clinical trial evaluating family-based treatment for depressed adolescents (AHUS) has been terminated.
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CLINICAL_TRIALS research · 2018-04-20Clinical Trial Update: Night in Japan Home Sleep Monitoring Study
An update on an ongoing home sleep monitoring clinical study in Japan sponsored by Shiga University, exploring sleep initiation and maintena…
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: MDD POC Study GSK372475 Subjects Depressive Disease [Phase 2]
Phase 2 trial update for GSK372475 in depressive disorder shows completed status with results posted.
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CLINICAL_TRIALS trial_result · 2017-12-07Clinical Trial Update: Text-Message-Based Depression Prevention for High-Risk Youth in the ED [NA]
Completed clinical trial evaluating text-message-based depression prevention for high-risk youth in the emergency department; results posted…
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CLINICAL_TRIALS research · 2017-11-28Clinical Trial Update: Comorbid Mental Disease and Heart Disease in Men
This clinical trial update from Universite de Moncton discusses comorbidity of heart disease (acute coronary syndrome) with mental health co…
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CLINICAL_TRIALS research · 2017-11-07Clinical Trial Update: Comprehensive Acupuncture for Depressive Disorder With Comorbid Psychogenic Pain [EARLY_Phase 1]
Clinical trial update describing an early-phase (Phase 1) study of comprehensive acupuncture for depressive disorder with comorbid psychogen…
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CLINICAL_TRIALS research · 2017-11-06Clinical Trial Update: Effects of Transcranial Direct Current Stimulation (tDCS) on Individuals With Prader-Willi Syndrome [NA]
A clinical trial update examines the effects of transcranial direct current stimulation (tDCS) in individuals with Prader-Willi syndrome, in…
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CLINICAL_TRIALS trial_result · 2017-10-31Clinical Trial Update: Treatment Outcome of Vascular Depression
This completed University of Pennsylvania trial reports the treatment outcomes for vascular depression.
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Functional MRI Before and After Treatment for Depression [NA]
A terminated Stanford-sponsored clinical trial evaluated functional MRI before and after treatment for depression, with results posted in 20…
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CLINICAL_TRIALS trial_result · 2017-09-11Clinical Trial Update: Desvenlafaxine vs. Placebo Treatment of Chronic Depression [Phase 4]
Phase 4 trial comparing desvenlafaxine to placebo in chronic depression shows completed study with posted results.
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CLINICAL_TRIALS trial_result · 2017-08-28Clinical Trial Update: Effects of Psychoeducation of Relatives to Patients With Serious Mental Illness [NA]
A completed clinical trial studied the effects of psychoeducation for relatives of patients with serious mental illness, including schizophr…
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CLINICAL_TRIALS trial_result · 2017-08-18Clinical Trial Update: Cytochrome P450-2D6 Screening Among Elderly Using Antidepressants (CYSCE) [Phase 4]
A Phase 4 clinical trial evaluating CYP2D6 metabolic screening in elderly patients taking antidepressants for depression has completed, inve…
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CLINICAL_TRIALS trial_result · 2017-08-10Clinical Trial Update: A Study To Evaluate The Effect Of WELLBUTRIN XL On Intraocular Pressure [Phase 1]
Phase 1 study assessing whether WELLBUTRIN XL (bupropion extended-release) affects intraocular pressure in individuals with depressive disor…
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CLINICAL_TRIALS trial_result · 2017-08-04Clinical Trial Update: 28-day Repeat Dose and Drug Interaction Study With Orvepitant (GW823296) [Phase 1]
A Phase 1 clinical trial update reports results from a 28-day repeat-dose and drug interaction study of Orvepitant (GW823296) in depressive …
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CLINICAL_TRIALS trial_result · 2017-08-04Clinical Trial Update: PAXIL CR Bioequivalence Study [Phase 1]
GlaxoSmithKline completed a Phase 1 bioequivalence study of Paxil CR (paroxetine controlled-release) for Depressive Disorder.