Dental Pulp Necrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Metagenomic Analysis and Postoperative Pain in Infected Root Canals Using Different Irrigation Protocols [NA]
This clinical trial update describes metagenomic analysis and postoperative pain evaluation in infected root canals using different irrigati…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: CTZ Paste for Emergency Dental Treatment in Public Health Settings: A Randomized Trial [EARLY_Phase 1]
An early-phase randomized trial evaluating CTZ Paste for emergency dental treatment in public health settings, currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Effect of 1% Melatonin Gel Versus Calcium Hydroxide as an Intracanal Medicament on the Intensity of Postoperative Pain, Bacterial Load Reduction and Periapical MMP-9 Levels in Patients With Necrotic Pulp. [NA]
Clinical trial comparing 1% melatonin gel to calcium hydroxide as intracanal medicaments in patients with dental pulp necrosis, assessing po…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Assessment of a New Apexification Method for Patients Presenting a Non Vital Immature Tooth [Phase 3]
Phase 3 trial update showing completion of a new apexification method for treating non-vital immature teeth in patients with dental pulp nec…
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: The Effect of Sealer Type and Obturation Technique on Postoperative Pain [NA]
A completed clinical trial evaluating whether sealer type and obturation technique affect postoperative pain in dental pulp necrosis.
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Influence of Maintaining Apical Patency on Post-Endodontic Pain in Molars [NA]
The document describes a clinical trial evaluating if maintaining apical patency affects post-endodontic pain in molars. The sponsor is Coll…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Chitosan Irrigation in Premolar Root Canal Therapy (Randomized Trial) [NA]
A clinical trial evaluating chitosan irrigation in premolar root canal therapy is currently recruiting patients with apical periodontitis, d…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Antimicrobial Efficacy of Four Different Irrigation Protocols [NA]
Completed Cairo University clinical trial evaluated the antimicrobial efficacy of four irrigation protocols for dental pulp necrosis; result…
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Pain and Microbial Reduction of Antimicrobial Corticosteroid Mixture Versus Cryotherapy in Necrotic Teeth [NA]
A completed clinical trial comparing an antimicrobial corticosteroid mixture to cryotherapy for reducing pain and microbial load in necrotic…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: One Vs Two Visits Root Canal Treatments in Infected Teeth [NA]
A Malmö University trial compares one-visit versus two-visit root canal treatment in teeth with apical periodontitis and dental pulp necrosi…
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CLINICAL_TRIALS withdrawal · 2023-09-21Clinical Trial Update: Nanodiamond-Gutta Percha Composite Biomaterials for Root Canal Therapy [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating nanodiamond-gutta percha composite biomaterials for root canal therapy has been withdrawn.
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CLINICAL_TRIALS trial_result · 2022-03-16Clinical Trial Update: Root Canal Treatment in Primary Molars With Necrotic Pulp Using Two Different Pulp Therapies [Phase 2]
Phase 2 trial updating outcomes for root canal treatment in primary molars with necrotic pulp comparing two pulp therapies.
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CLINICAL_TRIALS trial_result · 2022-01-13Clinical Trial Update: Nanodiamond Modified Gutta Percha (NDGP) Composite for Non-surgical Root Canal Therapy (RCT) Filler Material [NA]
Clinical trial completed evaluating nanodiamond-modified gutta-percha composite for non-surgical root canal therapy; results posted.
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CLINICAL_TRIALS trial_result · 2018-05-30Clinical Trial Update: Efficiency of Triple Antibiotic Paste, Ciprofloxacin/Propolis, Ciprofloxacin/Metronidazole, Propolis/Metronidazole Combinations on Revascularization Process of Immature Necrotic Maxillary Incisors of Patients 8-18 Years Old. [Phase 4]
Phase 4 trial evaluating four antibiotic regimens (Triple Antibiotic Paste; Ciprofloxacin/Propolis; Ciprofloxacin/Metronidazole; Propolis/Me…
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Reciprocation vs Rotational Single-file Systems in Postoperative Pain [NA]
This clinical trial compared Reciprocation versus Rotational Single-file systems for postoperative pain in teeth with apical periodontitis o…
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: Postoperative Pain and PTN and Reciproc [NA]
Clinical trial comparing ProTaper Next and Reciproc endodontic file systems for postoperative pain in apical periodontitis and dental pulp n…
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CLINICAL_TRIALS trial_result · 2017-11-07Clinical Trial Update: Comparison Between Reciproc and Protaper Next [NA]
A completed clinical trial comparing Reciproc and Protaper Next endodontic file systems in patients with dental pulp necrosis.
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: Antimicrobial Photodynamic Therapy Associated With the Conventional Endodontic Treatment: A Clinical and Microbiological Study [NA]
Completed clinical trial evaluating antimicrobial photodynamic therapy as an adjunct to conventional endodontic treatment for dental infecti…
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CLINICAL_TRIALS research · 2016-11-15Clinical Trial Update: Comparing Between XP Endo Finisher and Conventional Irrigation Method On Post-Operative Flare Ups In Necrotic Teeth [NA]
A clinical trial comparing XP Endo Finisher to a conventional irrigation method to assess post-operative flare-ups in teeth with dental pulp…
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CLINICAL_TRIALS trial_result · 2016-04-28Clinical Trial Update: Revitalization of Immature Permanent Teeth With Necrotic Pulps Using SHED Cells [NA]
An update on a clinical trial investigating revitalization of immature permanent teeth with necrotic pulps using SHED cells. The study is sp…
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CLINICAL_TRIALS trial_result · 2012-11-21Clinical Trial Update: Effect Of Different Lining Materials in Stepwise Excavation [Phase 2]
A Phase 2 clinical trial update evaluating different lining materials for stepwise excavation in dental pulp necrosis.
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CLINICAL_TRIALS trial_result · 2012-03-09Clinical Trial Update: Measurement of Bite Force in Humans
A completed clinical trial update describing the measurement of bite force in humans. The study addressed dental pulp necrosis and periapica…
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CLINICAL_TRIALS trial_result · 2008-02-27Clinical Trial Update: Efficacy of Chlorexidine as Intracanal Medicament in Primary Teeth [Phase 2]
Phase 2 trial evaluating chlorhexidine as an intracanal medicament in primary teeth reports efficacy data. The study is sponsored by Univers…