Dengue
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EMA approval · 2026-08-19EMA Authorised: Qdenga (Dengue virus, serotype 2, expressing Dengue virus, serotype 1, surface proteins, live, attenuated;Dengue virus, serotype 2, expressing Dengue virus, serotype 3, surface proteins, live, attenuated;Dengue virus, serotype 2, expressing Dengue virus, serotype 4, surface proteins, live, attenuated;Dengue virus, serotype 2, live, attenuated) — Takeda Pharmaceuticals International AG Ireland Branch
The EMA has authorised Qdenga, a live attenuated tetravalent dengue vaccine (serotypes 1, 2, 3, 4) by Takeda, for dengue prevention.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Improving Disease Prevention Strategies by Integrating Socio-spatial Characterization of Human Mobility
This clinical trial update from the Institute of Tropical Medicine, Belgium describes an active-not-recruiting study aimed at improving dise…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Therapeutics for Moderate and Severe Dengue [Phase 3]
Phase 3 clinical trial update for therapeutics targeting moderate and severe dengue indicates the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Demographic Characteristics of TAK-003 Dengue Vaccine Recipients in Vietnam
This clinical trial update describes the demographic characteristics of TAK-003 dengue vaccine recipients in Vietnam.
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Using Digital Technology for the Prevention of Aedes-Borne Diseases in Colombian Communities [NA]
Completed clinical trial in Colombia assessing digital technology for preventing dengue, Zika, and related Aedes-borne diseases.
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Study to Assess the Efficacy, Safety and Pharmacokinetics of EYU688 in Patients With Dengue Fever [Phase 2]
A Phase 2 trial evaluating the safety, efficacy and pharmacokinetics of EYU688 in patients with dengue fever is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Butantan-DV Vaccine in Elderly Populations (DEN-04-IB) [Phase 3]
Phase 3 clinical trial update of the Butantan-DV dengue vaccine in elderly populations; currently recruiting.
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: A Controlled Human Infection Model of Dengue [NA]
A clinical trial is evaluating a controlled human infection model for Dengue and is currently recruiting participants.
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Severe Dengue in Critical Care at Villavicencio, Colombia.
A clinical trial investigating severe dengue in critical care at Villavicencio, Colombia has completed. The study status is COMPLETED.
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EMA approval · 2026-01-30EMA Authorised: Qdenga (Dengue virus, serotype 2, expressing Dengue virus, serotype 1, surface proteins, live, attenuated;Dengue virus, serotype 2, expressing Dengue virus, serotype 3, surface proteins, live, attenuated;Dengue virus, serotype 2, expressing Dengue virus, serotype 4, surface proteins, live, attenuated;Dengue virus, serotype 2, live, attenuated) — Takeda Pharmaceuticals International AG Ireland Branch
The European Medicines Agency authorised Qdenga, a live attenuated tetravalent dengue vaccine from Takeda, for protection against dengue dis…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Dengvaxia US Pregnancy Registry
A US pregnancy registry for the dengue vaccine Dengvaxia is currently recruiting to collect data on pregnancy exposures and outcomes.
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Immunogenicity of an Intradermal Qdenga Vaccine Among Healthy Volunteers [EARLY_Phase 1]
This early Phase 1 trial evaluated the immunogenicity of intradermal Qdenga (TAK-003) dengue vaccine in healthy volunteers; results have bee…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Anakinra in Dengue With Hyperinflammation ( AnaDen ) [Phase 2]
Phase 2 trial evaluating the anti-inflammatory drug anakinra for dengue patients with hyperinflammation; the study is currently active but n…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Pilot Study to Detect DENGUE Virus in Sperm [NA]
A pilot clinical trial conducted at University Hospital, Toulouse to detect Dengue virus in sperm has completed; the snippet notes the compl…
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EMA withdrawal · 2025-12-04EMA Withdrawn: Dengvaxia (chimeric yellow fever dengue virus serotype 1 (live, attenuated);chimeric yellow fever dengue virus serotype 2 (live, attenuated);chimeric yellow fever dengue virus serotype 3 (live, attenuated);chimeric yellow fever dengue virus serotype 4 (live, attenuated)) — Sanofi Winthrop Industrie
The EMA has withdrawn Dengvaxia from use in the European Union.
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Clinical Bridging Study Between V181 (Dengue Quadrivalent Vaccine rDENVΔ30 [Live, Attenuated]) to Butantan Dengue Vaccine (Butantan - DV) in Healthy Adults 18 to 50 Years of Age in Brazil (V181 - 002) [Phase 2]
Phase 2 bridging trial comparing V181 (Dengue Quadrivalent Vaccine rDENVΔ30 [Live, Attenuated]) to the Butantan Dengue Vaccine (DV) in healt…
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: Study to Examine the Effects of Oral Fenretinide [Phase 2]
Phase 2 trial evaluating oral fenretinide for dengue has completed.
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Understanding the Public Impact on Dengue Vaccination Strategies in Yunnan Province, China: A Dynamic Transmission Modeling Study
This clinical trial update reports on a dynamic transmission modeling study assessing the public health impact of dengue vaccination strateg…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Dengue - Sample Collection Study Pakistan
A dengue sample collection study in Pakistan sponsored by Abbott Rapid Dx is registered and not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Quantifying the Epidemiological Impact of Targeted Indoor Residual Spraying on Aedes-borne Diseases [NA]
Emory University completed a trial evaluating the epidemiological impact of targeted indoor residual spraying on Aedes-borne diseases. Resul…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Risk Factors for Hospitalization and Transfusion Criteria in Patients With Dengue Virus Infection
This clinical trial update describes a study investigating risk factors for hospitalization and transfusion thresholds in patients with deng…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Evaluation of T-cell Responses After Vaccination With the Attenuated Tetravalent Dengue Vaccine (Takeda).
This clinical trial update reports on evaluating T-cell immune responses after vaccination with Takeda's attenuated tetravalent dengue vacci…
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: A Study of JNJ-64281802 for the Prevention of Dengue Infection [Phase 2]
A Phase 2 study of JNJ-64281802 for the prevention of dengue infection was terminated, with results posted on 2025-07-31.
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Immune Responses to Dengue and Sepsis
A clinical trial update describing an immunology study on immune responses to Dengue and Sepsis, sponsored by Institut Pasteur du Cambodge, …
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: The Comparative Efficacy of Standard Treatment Plus Ribavirin vs Standard Treatment Alone in Preventing Clinically Significant Hemorrhage in Patients With Dengue Fever [Phase 3]
Phase 3 randomized trial evaluating whether adding ribavirin to standard dengue treatment reduces clinically significant hemorrhage compared…