Decompensated Cirrhosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: New Prognostic Predictive Models of Mortality of Decompensated Cirrhotic Patients Waiting for Liver Transplantation [NA]
This study completed development of predictive models to estimate mortality risk for patients with decompensated cirrhosis awaiting liver tr…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: A Study to See if an Investigational Medicine Called VS-01 Can Help and How Safe it is in the Treatment of Patients With Overt Hepatic Encephalopathy [Phase 2]
Genfit's Phase 2 trial of the investigational medicine VS-01 for hepatic encephalopathy in patients with acute-on-chronic liver failure and …
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Concordance Between Echocardiographic Assessment Performed in the Initial Phase of Decompensated Cirrhosis With Edema and Ascites by an Expert Intensive Care Physician and a Non-expert Gastroenterologist
This clinical trial update evaluates concordance between echocardiographic assessments performed by an expert intensive care physician and a…
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Introducing Palliative Care (PC) Within the Treatment of End Stage Liver Disease (ESLD) [NA]
A clinical trial evaluating the integration of palliative care into the treatment of end-stage liver disease has completed, with results pos…
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: Effects of Long-Term Administration of Human Albumin in Participants With Decompensated Cirrhosis and Ascites [Phase 3]
Phase 3 trial evaluating long-term administration of human albumin in people with decompensated cirrhosis and ascites has completed and resu…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Coagulation Parameters With Albumin in Decompensated Cirrhosis (CoPA-D). [NA]
CoPA-D is a completed clinical trial evaluating the effect of albumin on coagulation parameters in patients with Decompensated cirrhosis.
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Low-dose Albumin Infusion for the Prevention of Paracentesis Induced Circulatory Dysfunction (PICD), After Large Volume Paracentesis (LVP) in Decompensated Cirrhosis Liver. [Phase 4]
Phase 4 clinical trial conducted in Bangladesh completed evaluating low-dose albumin infusion to prevent paracentesis-induced circulatory dy…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Effect of Albumin Infusion on Oxidative Albumin Modification, Albumin Binding Capacity and Plasma Thiol Status
A completed clinical trial evaluated the effect of albumin infusion on oxidative modification of albumin, albumin binding capacity, and plas…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: A Study for Evaluation of BIV201 to Reduce Ascites and Complications in Patients With Cirrhosis and Refractory Ascites [Phase 2]
Phase 2 study evaluating BIV201 to reduce ascites and complications in patients with cirrhosis and refractory ascites has been terminated.
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CLINICAL_TRIALS trial_result · 2023-01-06Clinical Trial Update: Primary Prophylaxis for Spontaneous Bacterial Peritonitis [Phase 2, Phase 3]
A Phase 2/3 clinical trial investigating primary prophylaxis for spontaneous bacterial peritonitis in decompensated cirrhosis has been termi…
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CLINICAL_TRIALS trial_result · 2021-11-16Clinical Trial Update: Treatment With Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis [Phase 2]
Phase 2 clinical trial evaluating human umbilical cord-derived mesenchymal stem cells for decompensated cirrhosis.
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CLINICAL_TRIALS trial_result · 2021-06-07Clinical Trial Update: Avatrombopag in Patients With End-stage Liver Disease and Thrombocytopenia [Phase 4]
Phase 4 trial investigating avatrombopag for thrombocytopenia in patients with liver failure and related conditions, status currently unknow…
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CLINICAL_TRIALS trial_result · 2020-12-16Clinical Trial Update: Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-17
A companion protocol update for a methacetin breath test in the Meridian Bioscience study (NCT03462576) related to decompensated cirrhosis; …
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Injectable Collagen Scaffold™ Combined With HUC-MSCs Transplantation for Patients With Decompensated Cirrhosis [Phase 1, Phase 2]
Phase 1/2 trial investigating Injectable Collagen Scaffold™ combined with human umbilical cord mesenchymal stem cells for decompensated cirr…
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CLINICAL_TRIALS trial_result · 2019-03-19Clinical Trial Update: Emricasan, a Caspase Inhibitor, for Treatment of Subjects With Decompensated NASH Cirrhosis [Phase 2]
Phase 2 clinical trial update for emricasan, a caspase inhibitor, in subjects with decompensated cirrhosis due to non-alcoholic steatohepati…
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CLINICAL_TRIALS trial_result · 2019-01-17Clinical Trial Update: Early TIPS With Polytetrafluoroethylene (PTFE) Covered Stents for Acute Variceal Bleeding in Patients With Advanced Cirrhosis [NA]
Clinical trial update on early transjugular intrahepatic portosystemic shunt (TIPS) using PTFE-covered stents for acute variceal bleeding in…
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With Ribavirin in Adults With Genotype 1 and Ombitasvir/Paritaprevir/Ritonavir With Ribavirin in Adults With Genotype 4 Chronic Hepatitis C Virus Infection and Decompensated Cirrhosis [Phase 3]
Phase 3 trial evaluating the safety and efficacy of ombitasvir/paritaprevir/ritonavir with dasabuvir and ribavirin in adults with genotype 1…
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: To Study The Incidence And Outcome Of Paracentesis Induced Circulatory Dysfunction in Decompensated Cirrhotics Undergoing Less Than 5 Litres Of Ascitic Fluid Tap With Or Without Albumin Infusion. [NA]
This ClinicalTrials.gov study evaluated the incidence and outcomes of paracentesis-induced circulatory dysfunction in patients with decompen…
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CLINICAL_TRIALS trial_result · 2017-01-09Clinical Trial Update: Fecal Microbiota Transplantation for Decompensated Cirrhosis [Phase 1, Phase 2]
This document reports an ongoing Phase 1/2 clinical trial evaluating fecal microbiota transplantation for decompensated cirrhosis; the curre…
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CLINICAL_TRIALS trial_result · 2016-11-22Clinical Trial Update: A Trial to Study the Influence of Growth Factors on Bone Marrow and Hepatic Regeneration in Patients With Decompensated Cirrhosis. [NA]
A completed clinical trial studying the influence of growth factors on bone marrow and hepatic regeneration in patients with decompensated c…
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CLINICAL_TRIALS trial_result · 2016-10-18Clinical Trial Update: To Assess the Efficacy of Granulocyte Colony Stimulating Factor Versus Standard Medical Therapy in Patients of Decompensated Cirrhosis [Phase 3]
A Phase 3 trial evaluating granulocyte colony-stimulating factor versus standard medical therapy in decompensated cirrhosis has completed.
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: Sofosbuvir and Ribavirin in Patients With Chronic HCV With Cirrhosis and Portal Hypertension With or Without Liver Decompensation [Phase 2]
Phase 2 trial evaluating sofosbuvir and ribavirin in adults with chronic hepatitis C and cirrhosis, including patients with portal hypertens…
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CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: TIPS With 8- OR 10-mm Covered Stent for Preventing Variceal Rebleeding [NA]
A completed clinical trial evaluated using 8- or 10-mm covered stents for transjugular intrahepatic portosystemic shunt (TIPS) to prevent va…
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CLINICAL_TRIALS trial_result · 2015-08-03Clinical Trial Update: Biomarkers for the Prognosis of Decompensated Alcoholic Liver Disease
A completed University of Nottingham clinical trial investigated biomarkers to predict prognosis in decompensated alcoholic liver disease.
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CLINICAL_TRIALS trial_result · 2014-02-28Clinical Trial Update: Rifaximin Predicts the Complications of Decompensated Cirrhosis [Phase 4]
Phase 4 trial update evaluating rifaximin for predicting complications in patients with decompensated cirrhosis.