Cytomegalovirus Retinitis
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CLINICAL_TRIALS trial_result · 2021-11-04Clinical Trial Update: The Safety and Effectiveness of Ganciclovir in the Prevention of Cytomegalovirus (CMV) of the Eyes and Disease of the Stomach and Intestines in Patients With HIV [Phase 2]
Phase 2 trial assessing safety and effectiveness of ganciclovir for CMV-related eye and GI diseases in HIV patients; study completed.
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CLINICAL_TRIALS trial_result · 2021-11-03Clinical Trial Update: A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure [Phase 2]
Phase II dose-ranging, open-label trial evaluating foscarnet salvage therapy for AIDS patients with sight-threatening CMV retinitis who cann…
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CLINICAL_TRIALS trial_result · 2021-11-01Clinical Trial Update: Comparison of Two Methods in the Treatment of Cytomegalovirus of the Eyes in Patients With AIDS [Phase 2]
Phase 2 clinical trial comparing two treatment methods for cytomegalovirus retinitis in AIDS patients; study completed.
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: High-dose Intravitreal Injection of Ganciclovir for the Treatment of CMVR in HIV-negative Patients [NA]
Completion of a clinical trial evaluating high-dose intravitreal ganciclovir for cytomegalovirus retinitis in HIV-negative patients is repor…
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: A Comparison of Valganciclovir and Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes [Phase 3]
A Phase 3 trial comparing valganciclovir with ganciclovir for the treatment of cytomegalovirus retinitis in HIV-infected patients has comple…
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CLINICAL_TRIALS trial_result · 2016-03-14Clinical Trial Update: Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT) [Phase 3]
Phase 3 study evaluating ganciclovir and cidofovir for CMV retinitis in AIDS patients; the trial is completed and results were posted in 201…
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: Studies of the Ocular Complications of AIDS (SOCA)--HPMPC Peripheral CMV Retinitis Trial (HPCRT) [Phase 2, Phase 3]
Clinical trial update for the SOCA HPCRT study evaluating HPMPC (cidofovir) for CMV retinitis in HIV/AIDS patients; the Phase 2/Phase 3 tria…
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: Studies of the Ocular Complications of AIDS (SOCA)--Monoclonal Antibody CMV Retinitis Trial (MACRT) [Phase 2, Phase 3]
Phase 2/3 trial evaluating a CMV-specific monoclonal antibody for ocular complications in AIDS patients with Cytomegalovirus retinitis; resu…
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CLINICAL_TRIALS trial_result · 2015-10-22Clinical Trial Update: Studies of the Ocular Complications of AIDS (SOCA)--Foscarnet-Ganciclovir CMV Retinitis Trial (FGCRT) [Phase 3]
Phase 3 clinical trial update for FGCRT evaluating combination therapy with Foscarnet and Ganciclovir for CMV retinitis in individuals with …
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CLINICAL_TRIALS trial_result · 2015-09-14Clinical Trial Update: Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT) [Phase 3]
Phase 3 trial update from the SOCA studies on Cytomegalovirus retinitis retreatment in HIV/AIDS patients; results for the CRRT have been pos…
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: Longitudinal Study of Ocular Complications of AIDS (LSOCA)
This entry notes that the Longitudinal Study of Ocular Complications of AIDS (LSOCA) sponsored by Johns Hopkins has completed.
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CLINICAL_TRIALS trial_result · 2013-06-05Clinical Trial Update: Pharmacokinetics of Cidofovir During Continuous Venovenous Hemofiltration [Phase 4]
A Phase 4 study assessing cidofovir pharmacokinetics during continuous venovenous hemofiltration in patients with cytomegalovirus retinitis …
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CLINICAL_TRIALS trial_result · 2012-11-01Clinical Trial Update: HPMPC (Cidofovir) Peripheral CMV Retinitis Trial Protocol [NA]
This entry notes completion of a clinical trial protocol evaluating cidofovir (HPMPC) for peripheral cytomegalovirus retinitis in HIV-infect…
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CLINICAL_TRIALS trial_result · 2012-10-25Clinical Trial Update: A Phase II/III Trial of Human Anti-CMV Monoclonal Antibody MSL 109 (MACRT) [Phase 2]
This document provides an update on a Phase II/III trial evaluating the human anti-CMV monoclonal antibody MSL-109 (MACRT) for cytomegalovir…
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CLINICAL_TRIALS trial_result · 2011-03-14Clinical Trial Update: A Randomized, Controlled Study of Intravenous Ganciclovir Therapy for Peripheral Cytomegalovirus Retinitis in Patients With AIDS [Phase 3]
This completed Phase 3 randomized trial evaluated intravenous ganciclovir for peripheral cytomegalovirus retinitis in patients with AIDS.
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CLINICAL_TRIALS trial_result · 2011-03-14Clinical Trial Update: Studies of the Ocular Complications of AIDS (SOCA) CMV Retinitis Trial: Foscarnet-Ganciclovir Component [NA]
Clinical trial update for the SOCA study evaluating foscarnet-ganciclovir in CMV retinitis associated with AIDS; the study status is complet…
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CLINICAL_TRIALS trial_result · 2011-03-01Clinical Trial Update: CMV Retinitis Retreatment Trial [Phase 2]
A Phase 2 retreatment trial investigating cytomegalovirus retinitis in HIV-infected individuals has completed.
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CLINICAL_TRIALS trial_result · 2011-02-23Clinical Trial Update: Comparison of Two Drugs, Cidofovir and Ganciclovir, in Treating Patients With AIDS Who Have CMV Retinitis [Phase 4]
Phase 4 trial comparing cidofovir and ganciclovir for cytomegalovirus retinitis in HIV/AIDS patients has completed.
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CLINICAL_TRIALS trial_result · 2009-09-17Clinical Trial Update: Ganciclovir Implant Study for Cytomegalovirus Retinitis [Phase 3]
A Phase 3 study evaluating a ganciclovir implant for cytomegalovirus retinitis has completed.
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CLINICAL_TRIALS trial_result · 2008-09-30Clinical Trial Update: A Treatment Protocol for the Use of Intravenous Ganciclovir in AIDS Patients With Immediately Sight-Threatening CMV Retinitis [Phase 3]
Phase 3 trial evaluating intravenous ganciclovir for immediately sight-threatening cytomegalovirus retinitis in AIDS patients has completed.
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CLINICAL_TRIALS trial_result · 2008-08-04Clinical Trial Update: A Comparison of HIV-Infected Patients With and Without Opportunistic (AIDS-Related) Infection
This clinical trial compares HIV-infected patients with and without AIDS-related opportunistic infections, examining outcomes related to cyt…
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: A Study to Evaluate the Effects of Stopping Maintenance Therapy for Cytomegalovirus (CMV) Retinitis After Effective Anti-HIV Therapy
A completed clinical trial assessing whether stopping maintenance therapy for Cytomegalovirus Retinitis is safe after effective anti-HIV the…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Efficacy of Elevated CD4 Counts on CMV Retinitis
This completed clinical trial evaluated whether elevated CD4 counts improve outcomes in cytomegalovirus retinitis among individuals with acq…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Immune Activity Against CVM Retinitis
A completed clinical trial evaluated immune activity against Cytomegalovirus retinitis in individuals with Acquired Immunodeficiency Syndrom…