Cytokine Release Syndrome
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Continuous Temperature Monitoring (CTM) for Cytokine Release Syndrome (CRS), an Immune-Related Adverse Event [NA]
ClinicalTrials.gov update describes a study on continuous temperature monitoring to detect cytokine release syndrome during immunotherapy, w…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Ruxolitinib With and Without CTLA-4 Ig Abatacept for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation [Phase 1]
A Phase 1 clinical trial is evaluating ruxolitinib with and without abatacept (CTLA-4Ig) for prophylaxis of graft-versus-host disease and cy…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Early Detection of Complications During Immunotherapy for Haematological Malignancy [NA]
Clinical trial update from Rigshospitalet, Denmark on early detection of complications during immunotherapy for hematologic cancer, includin…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Tadekinig Alfa (IL-18BP) Rescue Therapy for CAR T Cell Related Cytokine Release Syndrome (CRS) and HLH-like Syndrome [EARLY_Phase 1]
Early-phase Phase 1 trial evaluating tadekinig alfa, an interleukin-18 binding protein, as rescue therapy for CAR T cell–related cytokine re…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Adjunctive Methylene Blue for Immunotherapy-related CRS and ICANS: Phase I Study [Phase 1]
Phase I study evaluating adjunctive methylene blue for immunotherapy-related cytokine release syndrome and ICANS; recruiting in China.
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: A Phase II Study of Siltuximab for CRS/ICANs After CAR-T in Multiple Myeloma [Phase 2]
This is an update on a Phase II clinical trial evaluating siltuximab for preventing or treating CRS/ICANs after CAR-T therapy in patients wi…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Study of Cytokine Release Syndrome Prophylaxis and Treatment With Siltuximab Prior to Epcoritamab [Phase 1]
A Phase 1 clinical trial is investigating prophylaxis and treatment of cytokine release syndrome with siltuximab prior to epcoritamab in non…