Cutaneous Squamous Cell Carcinoma of the Head and Neck
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation [NA]
A clinical trial update describes remote audiometry being studied to monitor treatment-related hearing loss in patients with head and neck s…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation Therapy [Phase 2]
Phase 2 trial evaluating pain management regimens using gabapentin, methadone, and oxycodone with or without venlafaxine in patients with cu…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Evaluation of Skin Tests in Biotherapy Allergies [NA]
A University Hospital, Angers-sponsored trial evaluating skin tests in biotherapy allergies is NOT_YET_RECRUITING. The study lists Locally A…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Pembrolizumab for the Treatment of Locally Advanced and/or Recurrent Orbital or Periocular Cutaneous Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial update indicates pembrolizumab is being studied for locally advanced and/or recurrent orbital or periocular cutaneo…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Surveillance of Regional Nodal Basins in Patients With Primary High Risk Cutaneous Squamous Cell Carcinoma of the Head and Neck
A Johns Hopkins University-sponsored clinical trial investigating surveillance of regional nodal basins in high-risk cutaneous squamous cell…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 3]
Phase 3 trial evaluating combining radiation therapy with immunotherapy for metastatic and stage IV squamous cell carcinomas of the head and…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Impact of Preoperative High-Frequency Ultrasound Cutaneous Lesion Extent Assessment on Excision Margin Positivity in Head and Neck Skin Cancer, and the Relationship Between Preoperative Assessment Methods, Inadequate Excision Margins, and Tumor Recurrence
A clinical trial update evaluating whether preoperative high-frequency ultrasound assessment of skin lesion extent reduces excision-margin p…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: (89Zr Panitumumab) With PET/CT for Diagnosing Metastases in Patients With Head and Neck Squamous Cell Carcinoma [Phase 1]
Phase 1 clinical trial evaluating 89Zr-labeled panitumumab with PET/CT for diagnosing metastases in head and neck squamous cell carcinoma; c…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Quad Shot Radiotherapy in Combination With Immune Checkpoint Inhibition [Phase 2]
Phase 2 trial evaluating quad-shot radiotherapy in combination with an immune checkpoint inhibitor for advanced and recurrent head and neck …
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Magnetic Resonance (MR) Imaging & Blood Biomarkers for Head and Neck Cancer
Clinical trial update on using MR imaging and blood biomarkers for head and neck cancer, including cutaneous squamous cell carcinoma of the …
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Phase 2 Pragmatic Trial of Sentinel Lymph Node Biopsy (SLNB) in Patients With Clinically Node-Negative (cN0), High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck [Phase 2]
Phase 2 pragmatic trial evaluating sentinel lymph node biopsy in high-risk clinically node-negative cutaneous squamous cell carcinoma of the…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Towards Cure Via Only Ultra-short ICB in CSCC [Phase 2]
The Netherlands Cancer Institute is conducting a Phase 2 trial in cutaneous squamous cell carcinoma using ultra-short immune checkpoint bloc…
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck Cancer [Phase 1]
Phase 1 study evaluating adding BAY 1895344 with radiation therapy to pembrolizumab for recurrent head and neck squamous cell carcinomas, ai…
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CLINICAL_TRIALS withdrawal · 2024-07-25Clinical Trial Update: Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer [Phase 2]
Phase 2 trial evaluating Xevinapant added to standard radiation therapy plus cisplatin/carboplatin for head and neck cancers has been withdr…
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CLINICAL_TRIALS trial_result · 2023-09-05Clinical Trial Update: Atezolizumab Before Surgery for the Treatment of Regionally Metastatic Head and Neck Squamous Cell Cancer With an Unknown or Historic Primary Site [Phase 2]
Phase 2 trial update evaluating atezolizumab before surgery in regionally metastatic head and neck cutaneous squamous cell carcinoma; the st…
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CLINICAL_TRIALS trial_result · 2022-07-14Clinical Trial Update: Cemiplimab-rwlc for Unresectable Locally Recurrent and/or Metastatic CSCC [Phase 2]
Phase 2 trial of cemiplimab-rwlc for unresectable locally recurrent and/or metastatic cutaneous squamous cell carcinoma has terminated with …
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CLINICAL_TRIALS trial_result · 2022-05-10Clinical Trial Update: Post-operative Radiation With Cetuximab for Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck [Phase 2]
Phase 2 trial assessing postoperative radiation with cetuximab for locally advanced cutaneous squamous cell carcinoma of the head and neck c…