Cutaneous Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Study of a Strategy Integrating Adjuvant Radiation Therapy Versus Strategy Based on Monitoring in the Treatment of Carcinomas Spinocellular With High Risk of Recurrence [Phase 3]
A Phase 3 clinical trial compares an adjuvant radiation therapy strategy to a monitoring-based strategy for high-risk cutaneous squamous cel…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer [Phase 3]
A Phase 3 trial is evaluating adding cemiplimab to surgery versus surgery alone for advanced eyelid and other cutaneous squamous cell carcin…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
AstraZeneca is conducting a Phase 1/2 trial to evaluate the safety of AZD6750 in adults with select advanced or metastatic solid tumors; the…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune System [Phase 2]
Phase 2 clinical trial update examining amivantamab with hyaluronidase or cetuximab for advanced cutaneous squamous cell carcinoma in people…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial update evaluating RP1 in adults with organ transplants and advanced skin cancers, including Merkel cell carcinoma…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma [Phase 3]
Phase 3 study evaluating intralesional cemiplimab in adults with early-stage cutaneous squamous cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Phase 2 Study of Ivonescimab in Patients With Cutaneous Squamous Cell Carcinoma [Phase 2]
This ClinicalTrials.gov entry reports a Phase 2 study evaluating Ivonescimab in patients with cutaneous squamous cell carcinoma, currently r…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Phase Ib/II Study of an Anti-HER3 Antibody, HMBD-001, With Cetuximab +/- Docetaxel in Advanced Squamous Cell Cancers [Phase 1, Phase 2]
A Phase Ib/II clinical trial evaluating HMBD-001, an anti-HER3 antibody, in combination with cetuximab with or without docetaxel for advance…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Study of TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 study of TransCon TLR7/8 agonist with or without pembrolizumab in patients with advanced or metastatic solid tumors has been ter…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas [Phase 1]
Phase 1 study evaluating safety, efficacy, and pharmacokinetics of EVOLVE104 in patients with advanced urothelial cancer and squamous cell c…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Microneedle Array Plus Doxorubicin in Cutaneous Squamous Cell Cancer (cSCC) [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating a microneedle array delivering doxorubicin for cutaneous squamous cell carcinoma, and the study is …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer [Phase 3]
Phase 3 trial assessing high-dose prophylactic gabapentin to prevent opioid use for oral mucositis pain during chemoradiation in head and ne…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Cutaneous Squamous Cell Carcinoma Staging Study
This clinical trial update indicates that a staging study for Cutaneous Squamous Cell Carcinoma sponsored by Queen Mary University of London…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Transplant Recipients [EARLY_Phase 1]
A randomized controlled trial evaluating topical 5% niacinamide for prevention of skin cancer in organ transplant recipients is in early pha…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Studying Off Label Insurance Coverage for Patients With Cutaneous Cancers a "Filter" Observational Study
An observational study examining off-label insurance coverage for patients with select cutaneous cancers, sponsored by Ohio State University…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Study of Afatinib in Advanced Cutaneous Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating afatinib for advanced cutaneous squamous cell carcinoma; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: ctDNA in Cutaneous Squamous Cell Carcinoma
A clinical trial investigating circulating tumor DNA (ctDNA) in patients with cutaneous squamous cell carcinoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Study of (Neo)Adjuvant Intismeran Autogene (V940) and Pembrolizumab in Cutaneous Squamous Cell Carcinoma (V940-007) [Phase 2, Phase 3]
A phase 2/3 study of Intismeran Autogene (V940) in combination with pembrolizumab for cutaneous squamous cell carcinoma (V940-007) has compl…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study of Adjuvant Cemiplimab Versus Placebo After Surgery and Radiation Therapy in Patients With High Risk Cutaneous Squamous Cell Carcinoma [Phase 3]
Phase 3 trial evaluating adjuvant cemiplimab versus placebo after surgery and radiation for high-risk cutaneous squamous cell carcinoma. The…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Neoadjuvant PD-1 Inhibitor and EGFR Inhibitor in Locally Advanced Cutaneous Squamous Cell Carcinoma [Phase 2]
This clinical trial update describes a Phase 2 neoadjuvant study combining a PD-1 inhibitor with an EGFR inhibitor for locally advanced cuta…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: FLASH Radiotherapy for Skin Cancer [NA]
The clinical trial update indicates that the FLASH radiotherapy study for skin cancers is currently active but not recruiting, sponsored by …
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Exercise to Boost Response to Checkpoint Blockade Immunotherapy [NA]
Clinical trial update describes an active-not-recruiting study investigating whether exercise can boost response to checkpoint blockade immu…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Study of Favezelimab Coformulated With Pembrolizumab (MK-4280A) in Participants With Selected Solid Tumors (MK-4280A-010) [Phase 2]
Phase 2 study MK-4280A-010 evaluating favezelimab coformulated with pembrolizumab in selected solid tumors has completed.
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancers [Phase 2]
Phase 2 clinical trial evaluating EMLA Topical Cream to reduce pain from intradermal Tc-99 injections used for lymphoscintigraphy in patient…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma [Phase 2]
Phase 2 trial of L19IL2 and L19TNF in locally advanced cutaneous squamous cell carcinoma is not yet recruiting.