Cutaneous Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: A Safety Study of SEA-TGT (SGN-TGT) in Advanced Cancer [Phase 1]
Seagen's SEA-TGT (SGN-TGT) Phase 1 safety study in advanced cancers has been terminated. The study enrolled patients across multiple cancer …
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: Pembrolizumab, Standard Chemotherapy, Tumor Infiltrating Lymphocytes, and High- or Low-Dose Aldesleukin in Treating Patients With Metastatic Melanoma [Phase 2]
Phase 2 trial evaluating pembrolizumab with standard chemotherapy, tumor-infiltrating lymphocytes, and high- or low-dose aldesleukin in pati…
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: Ipilimumab and Nivolumab for the Treatment of Stage III-IV Unresectable Metastatic Melanoma [Phase 1]
A phase 1 trial evaluating the combination of ipilimumab and nivolumab for stage III/IV unresectable/metastatic cutaneous melanoma has been …
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: Binimetinib and Nivolumab for the Treatment of Locally Advanced Unresectable or Metastatic BRAF V600 Wildtype Melanoma [Phase 2]
This clinical trial update reports that the Phase 2 study of binimetinib plus nivolumab in BRAF V600 wildtype cutaneous melanoma has been te…
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Hepatic Ablation of Melanoma Metastases to Enhance Immunotherapy Response, a Phase I Clinical Trial (HAMMER I) [Phase 1]
HAMMER I is a Phase I trial evaluating hepatic ablation of melanoma liver metastases to enhance response to immunotherapy; the study status …
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Genetically Modified Therapeutic Autologous Lymphocytes Followed by Aldesleukin in Treating Patients With Stage III or Metastatic Melanoma [Phase 1, Phase 2]
Phase 1/2 study evaluating autologous genetically modified lymphocytes followed by Aldesleukin in patients with stage III or metastatic mela…
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors [Phase 1]
Phase 1 study of LY3300054, an anti-PD-L1 antibody, given alone or in combination in adults with advanced refractory solid tumors, including…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Study of Ipilimumab, Nivolumab, and Cabozantinib in Patients With Cutaneous Melanoma [Phase 2]
Phase 2 trial of ipilimumab, nivolumab, and cabozantinib in refractory cutaneous melanoma was terminated. Results have been posted.
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CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery [Phase 3]
A Phase 3 trial comparing high-dose recombinant interferon alfa-2B or ipilimumab to pembrolizumab in patients with surgically removed stage …
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CLINICAL_TRIALS trial_result · 2024-08-12Clinical Trial Update: Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma [Phase 2]
A Phase 2 trial evaluating denosumab in combination with a PD-1 inhibitor in stage III/IV melanoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Leveraging ctDNA Analysis to Improve Early Detection of Cancer Recurrence in the High-Risk Melanoma Setting
A completed clinical trial evaluated circulating tumor DNA (ctDNA) analysis as a tool for earlier detection of melanoma recurrence in high-r…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial assessing ipilimumab with or without bevacizumab in patients with unresectable stage IIIC/IV cutaneous melanoma; results were …
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CLINICAL_TRIALS trial_result · 2024-04-05Clinical Trial Update: Neoadjuvant and Adjuvant Checkpoint Blockade [Phase 2]
A Phase 2 neoadjuvant and adjuvant checkpoint blockade trial in melanoma completed with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic Melanoma [Phase 2]
Phase 2 trial evaluating lifileucel with reduced-dose fludarabine/cyclophosphamide lymphodepletion and interleukin-2 for unresectable or met…
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma [Phase 2]
Phase 2 trial evaluating the timing of pembrolizumab around surgery in high-risk melanoma, comparing post-operative administration to strate…
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CLINICAL_TRIALS trial_result · 2023-06-27Clinical Trial Update: Tacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic Cancers [Phase 1]
Phase 1 trial evaluating the combination of tacrolimus with immune checkpoint inhibitors nivolumab and ipilimumab in kidney transplant recip…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Endostar Plus Toripalimab as Adjuvant Therapy for Resectable Stage III-Oligometastatic Stage IV Cutaneous Melanoma [Phase 2]
A Phase 2 clinical trial evaluating Endostar in combination with toripalimab as adjuvant therapy for resectable stage III or oligometastatic…
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CLINICAL_TRIALS trial_result · 2023-05-01Clinical Trial Update: Testing Treatment With Ipilimumab and Nivolumab Compared to Treatment With Ipilimumab Alone in Advanced Melanoma [Phase 2]
A Phase 2 study compares the combination of ipilimumab and nivolumab versus ipilimumab alone in advanced melanoma, with results posted.
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CLINICAL_TRIALS trial_result · 2022-11-10Clinical Trial Update: Tumor-Infiltrating Lymphocytes After Combination Chemotherapy in Treating Patients With Metastatic Melanoma [Phase 2]
Phase 2 clinical trial evaluating tumor-infiltrating lymphocytes after combination chemotherapy in metastatic melanoma; results posted but n…
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CLINICAL_TRIALS trial_result · 2022-08-08Clinical Trial Update: pDNA Intralesional Cancer Vaccine for Cutaneous Melanoma [EARLY_Phase 1]
Early-phase trial update for a pDNA intralesional cancer vaccine in cutaneous melanoma (Stage III/IV) with results posted.
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CLINICAL_TRIALS trial_result · 2022-06-22Clinical Trial Update: Image Guided Hypofractionated Radiation Therapy, Nelfinavir Mesylate, Pembrolizumab, Nivolumab and Atezolizumab in Treating Patients With Advanced Melanoma, Lung, or Kidney Cancer [Phase 2]
Phase 2 trial investigating image-guided hypofractionated radiation therapy with nelfinavir mesylate and PD-1/PD-L1 inhibitors in advanced m…
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CLINICAL_TRIALS trial_result · 2022-04-19Clinical Trial Update: Safety, Tolerability, Immunogenicity, and Antitumor Activity of GEN-009 Adjuvanted Vaccine [Phase 1, Phase 2]
Phase 1/2 trial update reporting safety, tolerability, immunogenicity, and antitumor activity of GEN-009 adjuvanted vaccine in melanoma and …
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Immunization With 8 Peptides Mixed With CpG 7909 or Montanide ISA51 in Patients With Metastatic Cutaneous Melanoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating immunization with 8 peptides plus CpG 7909 or Montanide ISA51 in metastatic cutaneous melanoma; study status term…
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CLINICAL_TRIALS trial_result · 2022-01-19Clinical Trial Update: PV-10 vs Chemotherapy or Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous Melanoma [Phase 3]
Phase 3 trial comparing PV-10 to chemotherapy or oncolytic viral therapy for locally advanced cutaneous melanoma was terminated with posted …
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CLINICAL_TRIALS trial_result · 2021-11-16Clinical Trial Update: A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma [Phase 2]
Phase 2 trial evaluating CDX-1401 vaccine with or without CDX-301 for various-stage melanoma has completed enrollment with results posted.