Cutaneous Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Neo-adjuvant Immunotherapy in Patients With Localized Melanoma [Phase 2]
Phase 2 clinical trial update on neo-adjuvant immunotherapy for localized melanoma, currently recruiting.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Exercise to Boost Response to Checkpoint Blockade Immunotherapy [EARLY_Phase 1]
This clinical trial update describes an Early Phase 1 study at H. Lee Moffitt Cancer Center examining whether exercise can boost responses t…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: A Phase 2 Clinical Trial of Neoadjuvant Relatlimab and Nivolumab in High Risk, Clinical Stage II Cutaneous Melanoma [Phase 2]
Phase 2 neoadjuvant trial of relatlimab plus nivolumab in high-risk clinical stage II cutaneous melanoma; the study is currently active and …
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions [Phase 1, Phase 2]
A Phase 1/2 study evaluating darovasertib (IDE196), a PKC inhibitor, in patients with solid tumors harboring GNAQ/GNA11 mutations or PRKC fu…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: COmparison of the Use of a PERforator Flap Versus Total Skin GRAft in the Management of Loss of Substance After Resection of Cutaneous Melanoma - Pilot Study
This clinical trial registry entry outlines a pilot study comparing perforator flap reconstruction versus total skin grafting for managing t…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating natural killer cell therapy (UD TGFβi NK cells) in combination with temozolomide for patients with …
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Vemurafenib, Cobimetinib, Atezolizumab, and Tiragolumab in Treating Patients With High-Risk Stage III Melanoma [Phase 2]
Phase 2 trial update evaluating a four-drug combination (vemurafenib, cobimetinib, atezolizumab, and tiragolumab) for high-risk stage III cu…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform
An observational basket trial sponsored by Elephas aims to collect tissue to develop and train a live tumor diagnostic platform across multi…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program [Phase 2]
Phase 2 trial evaluating in-home versus in-clinic subcutaneous nivolumab administration under the CC Beyond Walls program; the study is curr…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Clear Me: Interception Trial to Detect and Clear Molecular Residual Disease in Patients With High-risk Melanoma [Phase 2]
A Phase 2 trial named Clear Me aims to detect and clear molecular residual disease in high-risk melanoma and is currently recruiting, includ…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of Patients With Brain Metastases From Cutaneous Melanoma [Phase 1, Phase 2]
An ongoing Phase 1/2 clinical trial evaluating defactinib and avutometinib, with or without encorafenib, in patients with brain metastases f…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors
This ClinicalTrials.gov entry describes a recruiting USC-led study evaluating social health, activity behaviors, and quality of life among y…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: The Impact of an Antibiotic (Cefazolin) Before Surgery on the Microbiome in Patients With Stage I-II Melanoma [Phase 1]
Phase 1 clinical trial evaluating whether preoperative Cefazolin affects the gut microbiome in patients with stage I–II cutaneous melanoma.
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: A Randomized Phase III Study of Management of Treatment Naive Primary Melanoma in Elderly Patients [Phase 3]
A Phase III randomized trial evaluating management of treatment-naive primary cutaneous melanoma in elderly patients is currently not recrui…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Time-of-Day Specified Immunotherapy for Advanced Melanoma, The TIME Trial [Phase 2]
Phase 2 trial evaluating time-of-day specified immunotherapy for advanced melanoma; currently recruiting.
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Symptoms of Immune Checkpoint Inhibitor Therapy in Cutaneous Melanoma
An UCSF-led clinical trial is recruiting to characterize symptoms experienced by patients with cutaneous melanoma treated with immune checkp…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Quality of Life, Lifestyle, and Psychosocial Factors in Patients With Melanoma
This clinical trial is evaluating quality of life, lifestyle factors, and psychosocial aspects in patients with cutaneous melanoma and is cu…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Hepatic Arterial Infusion of Autologous Tumor Infiltrating Lymphocytes in Patients With Melanoma and Liver Metastases [Phase 1]
Phase 1 trial evaluating hepatic arterial infusion of autologous tumor-infiltrating lymphocytes in patients with metastatic melanoma to the …
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Locoregional or Systemic Administration of Autologous Tumor Infiltrating Lymphocytes in Patients With Metastatic Melanoma [Phase 1]
A Phase 1 clinical trial is evaluating locoregional or systemic administration of autologous tumor-infiltrating lymphocytes in patients with…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases [Phase 2]
Phase 2 study compares encorafenib + binimetinib + nivolumab versus ipilimumab + nivolumab in BRAF-V600 mutation melanoma with brain metasta…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Guardant Health's ORACLE trial is currently recruiting to evaluate residual cancer using a liquid biopsy across multiple cancer types.
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Efficacy And Safety Of Anti-PD-1/PD-L1 Antibodies In Combination With Bevacizumab And Metronomic Cyclophosphamide In Patients With Non-Small Cell Lung Cancer And Cutaneous Melanoma Previously Treated With Immune Checkpoint Blockade [Phase 2]
Phase 2 clinical trial evaluating anti-PD-1/PD-L1 antibodies in combination with bevacizumab and metronomic cyclophosphamide in patients wit…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of APG-115 alone or with pembrolizumab in metastatic melanoma and other advanced solid tumors; the trial is currently active…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Research of Double-positive Circulating Cells (Tumor Marker / CD45+) in Several Types of Metastatic Cancers [NA]
A multi-cancer prospective study evaluating double-positive circulating cells (CD45+ tumor marker) in several types of metastatic cancers; r…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Tebentafusp in Molecular Relapsed Disease (MRD) Melanoma [Phase 2]
Phase 2 clinical trial update for tebentafusp in molecularly relapsed melanoma shows an active but not recruiting study targeting both cutan…