Cutaneous Lupus Erythematosus
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: Cutaneous Lupus Medication Experience Study
The Wake Forest University Health Sciences-sponsored clinical trial evaluating a medication experience in cutaneous lupus has completed (NCT…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Evaluation of Tofacitinib in Prevention of Photosensitivity in Lupus [Phase 1]
A Phase 1 study evaluating the JAK inhibitor tofacitinib for prevention of photosensitivity in cutaneous lupus has completed, with results p…
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositis [Phase 1]
Amgen's Phase 1 study evaluating VIB7734 in multiple autoimmune diseases including systemic lupus erythematosus, cutaneous lupus erythematos…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Identification of Cutaneous and Blood Biomarkers Predictive of Response to Systemic Treatments During Chronic Inflammatory Skin Diseases
This clinical trial update describes a study to identify cutaneous and blood biomarkers that predict response to systemic treatments across …
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CLINICAL_TRIALS trial_result · 2024-07-30Clinical Trial Update: Open-label Study of Tofacitinib for Moderate to Severe Skin Involvement in Young Adults With Lupus [Phase 1, Phase 2]
An open-label Phase 1/2 trial evaluating the JAK inhibitor tofacitinib for cutaneous lupus erythematosus and systemic lupus erythematosus in…
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CLINICAL_TRIALS research · 2024-07-19Clinical Trial Update: Characterizing Adherence to Treatment and Satisfaction With Care in Patients With Cutaneous Lupus
A clinical trial evaluating adherence to treatment and satisfaction with care in patients with cutaneous lupus erythematosus; currently recr…
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Proof of Concept Study of SAR443122 in Patients With Cutaneous Lupus Erythematosus [Phase 2]
Sanofi's SAR443122 completed a Phase 2 proof-of-concept study in patients with cutaneous lupus erythematosus; results have been posted.
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: Deep Phenotyping of Cutaneous Lupus Erythematosus [NA]
This clinical trial is recruiting to deeply phenotype Cutaneous Lupus Erythematosus to better understand its clinical and molecular features…
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CLINICAL_TRIALS trial_result · 2024-04-05Clinical Trial Update: Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE) [Phase 1]
Phase 1 study of edeCesertib in participants with Cutaneous Lupus Erythematosus was terminated, with results posted in 2024.
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CLINICAL_TRIALS research · 2023-08-25Clinical Trial Update: Low-dose UVA1 Radiation in Cutaneous Lupus Patients [NA]
Clinical trial completed assessing low-dose UVA1 radiation in patients with cutaneous lupus erythematosus; results posted in 2023.
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CLINICAL_TRIALS research · 2021-12-16Clinical Trial Update: Relevance of Monitoring Blood and Salivar Levels of Drugs Used in Rheumatic Autoimmune Diseases [Phase 4]
A Phase 4 trial evaluating the relevance of monitoring blood and salivary levels of drugs used in rheumatic autoimmune diseases, including S…
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CLINICAL_TRIALS trial_result · 2021-07-21Clinical Trial Update: Study of the Efficacy of 532nm Laser and 1064 nm Laser in the Treatment of Cutaneous Lupus Erythematous Versus Topical Corticosteroids Alone [NA]
Clinical trial evaluating laser therapy versus topical corticosteroids for cutaneous lupus erythematosus; study terminated with results post…
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CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: Nicotinamide Treatment for Lupus-associated Skin Lesions in Lupus Erythematosus [Phase 2]
A Phase 2 clinical trial is evaluating nicotinamide treatment for lupus-associated skin lesions in lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2020-06-23Clinical Trial Update: To Evaluate the Preliminary Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of CC-11050 in Subjects With Discoid Lupus Erythematosus and Subacute Cutaneous Lupus Erythematosus [Phase 2]
Phase 2 clinical trial assessing CC-11050 for safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy in discoid and subacute…
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CLINICAL_TRIALS trial_result · 2020-04-08Clinical Trial Update: Study to Evaluate Safety and Efficacy of Filgotinib and Lanraplenib in Females With Moderately-to-Severely Active Cutaneous Lupus Erythematosus (CLE) [Phase 2]
Phase 2 trial evaluating safety and efficacy of filgotinib and lanraplenib in females with moderately-to-severely active cutaneous lupus ery…
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CLINICAL_TRIALS trial_result · 2019-11-13Clinical Trial Update: Evaluation of Lenalidomide (REVLIMID®) to Treat Subjects With Cutaneous Lupus Erythematosus (CLE) [NA]
Clinical trial update on evaluating lenalidomide (REVLIMID) for treating cutaneous lupus erythematosus; status completed with results posted…
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CLINICAL_TRIALS trial_result · 2019-07-26Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Effect of GSK2646264 in Cutaneous Lupus Erythematosus Subjects [Phase 1]
Phase 1 study evaluating safety, tolerability, PK/PD, and clinical effect of GSK2646264 in adults with cutaneous lupus erythematosus; trial …
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CLINICAL_TRIALS withdrawal · 2018-06-28Clinical Trial Update: Cutaneous Lupus Erythematosus and Elidel [NA]
A clinical trial investigating Elidel (pimecrolimus) for cutaneous lupus erythematosus and discoid lupus erythematosus has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: Role of Proteasomes in a Dermatological Autoimmune Disease: Bullous Pemphigoid
A clinical trial investigating the role of proteasomes in bullous pemphigoid has been terminated; the study included bullous pemphigoid, pem…
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CLINICAL_TRIALS other · 2017-02-08Clinical Trial Update: European Society of Cutaneous Lupus Erythematosus (EUSCLE)
Clinical trial update from the European Society of Cutaneous Lupus Erythematosus (EUSCLE); the trial status is currently unknown.
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: A Study of Skin and Systemic Biomarkers In Patients With Active Cutaneous Lupus Erythematosus And In Healthy Volunteers
A completed study evaluating skin and systemic biomarkers in patients with active cutaneous lupus erythematosus and in healthy volunteers, s…
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CLINICAL_TRIALS trial_result · 2016-06-01Clinical Trial Update: Efficacy and Safety of Oral Alitretinoin (Toctino®) in the Treatment of Patients With Cutaneous Lupus Erythematosus [Phase 2]
A Phase 2 trial evaluated the efficacy and safety of oral alitretinoin (Toctino) in patients with cutaneous lupus erythematosus. The study s…
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CLINICAL_TRIALS trial_result · 2016-03-09Clinical Trial Update: Sunscreens in Patients With Cutaneous Lupus Erythematosus(CLE) [NA]
This clinical trial update notes the completion of a study evaluating the use of sunscreens in patients with cutaneous lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2015-08-10Clinical Trial Update: IVIg Efficacy Study to Treat Cutaneous Lupus Erythematosus [EARLY_Phase 1]
A Phase 1 study evaluating intravenous immunoglobulin (IVIg) for the treatment of cutaneous lupus erythematosus has completed, with results …
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CLINICAL_TRIALS trial_result · 2014-09-16Clinical Trial Update: Safety Study of AMG 811 in Subjects With Discoid Lupus Erythematosus [Phase 1]
Amgen conducted a Phase 1 safety study of AMG 811 in subjects with discoid lupus erythematosus, which has been terminated.