Cutaneous Lupus Erythematosus
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease [Phase 3]
Phase 3 study of enpatoran in participants with cutaneous lupus manifestations with or without systemic lupus erythematosus is currently rec…
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2) [Phase 3]
Phase 3 clinical trial of enpatoran in participants with cutaneous manifestations of lupus (with or without systemic disease) is currently r…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: A Study to Learn About the Study Medicine (PF-06823859) in Adults With Active CLE or SLE With Skin Symptoms. [Phase 2]
A Phase 2 study of PF-06823859 in adults with active lupus erythematosus with skin involvement has been terminated.
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE) [Phase 2]
A Phase 2 trial of Edecesertib for Cutaneous Lupus Erythematosus has been terminated.
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: The WILLOW Study With M5049 in SLE and CLE (SCLE and/or DLE) (WILLOW) [Phase 2]
The WILLOW Phase 2 study evaluated M5049 in systemic lupus erythematosus with cutaneous lupus erythematosus (SCLE/DLE) and has completed wit…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: A Study of KK4277 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus [Phase 1]
Phase 1 study of KK4277 in healthy volunteers and patients with systemic lupus erythematosus and cutaneous lupus erythematosus; the trial is…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: Cutaneous Lupus Medication Experience Study
The Wake Forest University Health Sciences-sponsored clinical trial evaluating a medication experience in cutaneous lupus has completed (NCT…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Evaluation of Tofacitinib in Prevention of Photosensitivity in Lupus [Phase 1]
A Phase 1 study evaluating the JAK inhibitor tofacitinib for prevention of photosensitivity in cutaneous lupus has completed, with results p…
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CLINICAL_TRIALS trial_result · 2024-07-30Clinical Trial Update: Open-label Study of Tofacitinib for Moderate to Severe Skin Involvement in Young Adults With Lupus [Phase 1, Phase 2]
An open-label Phase 1/2 trial evaluating the JAK inhibitor tofacitinib for cutaneous lupus erythematosus and systemic lupus erythematosus in…
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Proof of Concept Study of SAR443122 in Patients With Cutaneous Lupus Erythematosus [Phase 2]
Sanofi's SAR443122 completed a Phase 2 proof-of-concept study in patients with cutaneous lupus erythematosus; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-04-05Clinical Trial Update: Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE) [Phase 1]
Phase 1 study of edeCesertib in participants with Cutaneous Lupus Erythematosus was terminated, with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2021-07-21Clinical Trial Update: Study of the Efficacy of 532nm Laser and 1064 nm Laser in the Treatment of Cutaneous Lupus Erythematous Versus Topical Corticosteroids Alone [NA]
Clinical trial evaluating laser therapy versus topical corticosteroids for cutaneous lupus erythematosus; study terminated with results post…
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CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: Nicotinamide Treatment for Lupus-associated Skin Lesions in Lupus Erythematosus [Phase 2]
A Phase 2 clinical trial is evaluating nicotinamide treatment for lupus-associated skin lesions in lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2020-06-23Clinical Trial Update: To Evaluate the Preliminary Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of CC-11050 in Subjects With Discoid Lupus Erythematosus and Subacute Cutaneous Lupus Erythematosus [Phase 2]
Phase 2 clinical trial assessing CC-11050 for safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy in discoid and subacute…
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CLINICAL_TRIALS trial_result · 2020-04-08Clinical Trial Update: Study to Evaluate Safety and Efficacy of Filgotinib and Lanraplenib in Females With Moderately-to-Severely Active Cutaneous Lupus Erythematosus (CLE) [Phase 2]
Phase 2 trial evaluating safety and efficacy of filgotinib and lanraplenib in females with moderately-to-severely active cutaneous lupus ery…
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CLINICAL_TRIALS trial_result · 2019-11-13Clinical Trial Update: Evaluation of Lenalidomide (REVLIMID®) to Treat Subjects With Cutaneous Lupus Erythematosus (CLE) [NA]
Clinical trial update on evaluating lenalidomide (REVLIMID) for treating cutaneous lupus erythematosus; status completed with results posted…
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CLINICAL_TRIALS trial_result · 2019-07-26Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Effect of GSK2646264 in Cutaneous Lupus Erythematosus Subjects [Phase 1]
Phase 1 study evaluating safety, tolerability, PK/PD, and clinical effect of GSK2646264 in adults with cutaneous lupus erythematosus; trial …
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: Role of Proteasomes in a Dermatological Autoimmune Disease: Bullous Pemphigoid
A clinical trial investigating the role of proteasomes in bullous pemphigoid has been terminated; the study included bullous pemphigoid, pem…
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: A Study of Skin and Systemic Biomarkers In Patients With Active Cutaneous Lupus Erythematosus And In Healthy Volunteers
A completed study evaluating skin and systemic biomarkers in patients with active cutaneous lupus erythematosus and in healthy volunteers, s…
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CLINICAL_TRIALS trial_result · 2016-06-01Clinical Trial Update: Efficacy and Safety of Oral Alitretinoin (Toctino®) in the Treatment of Patients With Cutaneous Lupus Erythematosus [Phase 2]
A Phase 2 trial evaluated the efficacy and safety of oral alitretinoin (Toctino) in patients with cutaneous lupus erythematosus. The study s…
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CLINICAL_TRIALS trial_result · 2016-03-09Clinical Trial Update: Sunscreens in Patients With Cutaneous Lupus Erythematosus(CLE) [NA]
This clinical trial update notes the completion of a study evaluating the use of sunscreens in patients with cutaneous lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2015-08-10Clinical Trial Update: IVIg Efficacy Study to Treat Cutaneous Lupus Erythematosus [EARLY_Phase 1]
A Phase 1 study evaluating intravenous immunoglobulin (IVIg) for the treatment of cutaneous lupus erythematosus has completed, with results …
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CLINICAL_TRIALS trial_result · 2014-09-16Clinical Trial Update: Safety Study of AMG 811 in Subjects With Discoid Lupus Erythematosus [Phase 1]
Amgen conducted a Phase 1 safety study of AMG 811 in subjects with discoid lupus erythematosus, which has been terminated.
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CLINICAL_TRIALS trial_result · 2014-09-12Clinical Trial Update: A Non-drug Study Profiling Cutaneous Lupus
A completed non-drug clinical trial profiling cutaneous lupus and related lupus forms including cutaneous, systemic, and discoid lupus eryth…
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CLINICAL_TRIALS trial_result · 2014-05-13Clinical Trial Update: Multicenter Study Assessing the Efficacy & Safety of Hydroxychloroquine Sulfate in Patients With Systemic Lupus Erythematosus or Cutaneous Lupus Erythematosus With Active Lupus Erythematosus Specific Skin Lesion [Phase 3]
Phase 3 trial evaluating hydroxychloroquine sulfate for efficacy and safety in patients with systemic lupus erythematosus or cutaneous lupus…