Cryptococcal Meningitis
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: Optimizing the Dose of Flucytosine for the Treatment of Cryptococcal Meningitis [Phase 2]
Phase 2 trial results report on optimizing the dosing of flucytosine for cryptococcal meningitis, with results posted after completion. The …
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CLINICAL_TRIALS trial_result · 2023-12-21Clinical Trial Update: Amphotericin B for Non-HIV Cryptococcal Meningitis Patients [Phase 4]
Phase 4 trial update for Amphotericin B in non-HIV cryptococcal meningitis is currently enrolling by invitation.
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CLINICAL_TRIALS trial_result · 2023-04-12Clinical Trial Update: Single Dose Liposomal Amphotericin for Asymptomatic Cryptococcal Antigenemia [Phase 2, Phase 3]
Phase 2/3 clinical trial update evaluating single-dose liposomal amphotericin for asymptomatic cryptococcal antigenemia related to cryptococ…
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CLINICAL_TRIALS trial_result · 2023-03-31Clinical Trial Update: Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial (EnACT) [Phase 1, Phase 2]
Clinical trial update for Encochleated oral amphotericin for cryptococcal meningitis (EnACT) in Phase 1 and Phase 2, with completed status.
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CLINICAL_TRIALS trial_result · 2022-09-15Clinical Trial Update: Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial 3 [Phase 3]
A Phase 3 clinical trial evaluating encochleated oral amphotericin for cryptococcal meningitis is ongoing, with status currently unknown.
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CLINICAL_TRIALS trial_result · 2021-10-28Clinical Trial Update: Dexamethasone in Cryptococcal Meningitis [Phase 2]
Phase 2 trial update on dexamethasone for cryptococcal meningitis, completed.
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis [Phase 3]
Phase 3 trial evaluating adjunctive sertraline for HIV-associated cryptococcal meningitis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-12-02Clinical Trial Update: Treatment With Tamoxifen in Cryptococcal Meningitis [Phase 2]
A Phase 2 clinical trial evaluating tamoxifen for treatment of cryptococcal meningitis has been completed.
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CLINICAL_TRIALS trial_result · 2019-10-29Clinical Trial Update: AmB Dose for Cryptococcal Meningitis [Phase 3]
Phase 3 trial update examining AmB dose for cryptococcal meningitis; status is currently unknown.
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Vietnam Cryptococcal Retention in Care Study (CRICS) Federal Financial Report [Phase 1]
Phase 1 CRICS trial in Vietnam involving cryptococcal meningitis has completed and a Federal Financial Report has been filed.
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: High-Dose Fluconazole for the Treatment of Cryptococcal Meningitis in HIV-Infected Individuals [Phase 1, Phase 2]
Clinical trial update on high-dose fluconazole for cryptococcal meningitis in HIV patients; phases 1/2 completed with results posted.
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CLINICAL_TRIALS trial_result · 2016-07-18Clinical Trial Update: Early Versus Delayed Antiretroviral Therapy (ART) in the Treatment of Cryptococcal Meningitis in Africa [NA]
A completed clinical trial evaluating early versus delayed antiretroviral therapy in patients with cryptococcal meningitis and HIV infection…
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CLINICAL_TRIALS trial_result · 2016-02-22Clinical Trial Update: Efficacy of Intrathecal Administration of Liposomal Amphotericin B in Cryptococcal Meningitis [Phase 4]
Phase 4 trial evaluating intrathecal liposomal amphotericin B for cryptococcal meningitis. Current status is unknown.
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CLINICAL_TRIALS trial_result · 2016-01-18Clinical Trial Update: Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC [Phase 3]
A Phase 3 clinical trial in the Democratic Republic of Congo evaluating rapid diagnostic tests and clinical/laboratory predictors for cerebr…
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CLINICAL_TRIALS trial_result · 2014-03-28Clinical Trial Update: Clinical Outcomes of Cryptococcal Meningitis Among HIV-infected Patients in the Era of Antiretroviral Therapy
This is a completed clinical trial update on outcomes of cryptococcal meningitis in HIV-infected patients in the era of antiretroviral thera…
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CLINICAL_TRIALS trial_result · 2012-02-07Clinical Trial Update: Optimal Time to Start Antiretroviral Therapy in HIV-infected Adults With Cryptococcal Meningitis [Phase 4]
This Phase 4 clinical trial update reports results on the optimal timing of starting antiretroviral therapy in adults with HIV infection and…
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CLINICAL_TRIALS trial_result · 2011-03-14Clinical Trial Update: Comparison of Fluconazole and Amphotericin B in the Treatment of Brain Infections in Patients With AIDS [Phase 3]
Phase 3 clinical trial comparing fluconazole to amphotericin B for the treatment of cryptococcal meningitis in patients with AIDS has comple…
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CLINICAL_TRIALS trial_result · 2011-03-14Clinical Trial Update: Multi-center Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis [NA]
A multi-center trial comparing fluconazole and amphotericin B for acute cryptococcal meningitis in HIV-infected patients has completed.
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CLINICAL_TRIALS trial_result · 2010-06-23Clinical Trial Update: Amphotericin Alone or in Combination With Fluconazole for AIDS-Associated Meningitis [Phase 2]
A Phase 2 trial comparing amphotericin B alone versus amphotericin B combined with fluconazole for AIDS-associated cryptococcal meningitis c…
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CLINICAL_TRIALS trial_result · 2009-06-03Clinical Trial Update: Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis [Phase 2]
Phase 2 trial evaluating the safety and antifungal activity of recombinant interferon-gamma 1b added to standard therapy in cryptococcal men…
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CLINICAL_TRIALS trial_result · 2009-02-19Clinical Trial Update: Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS [Phase 2]
Phase 2 trial update evaluating the efficacy and safety of Mycograb as adjunctive therapy for cryptococcal meningitis in AIDS patients; the …
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CLINICAL_TRIALS trial_result · 2008-12-12Clinical Trial Update: Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS [Phase 2]
Phase 2 trial evaluating the efficacy and safety of Mycograb as adjunctive therapy for cryptococcal meningitis in AIDS patients has been ter…