Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-04-06Clinical Trial Update: A Dose-finding and Confirmatory Trial of OPC-6535 in Patients With Active Crohn's Disease [Phase 2, Phase 3]
Phase 2/3 trial of OPC-6535 in active Crohn's disease completed; results posted.
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CLINICAL_TRIALS trial_result · 2021-03-04Clinical Trial Update: A Research Study to Bank Samples for Future Evaluation to Identify Biomarkers That Predispose Crohn's Disease and Ulcerative Colitis Patients to Develop Hepatosplenic T-Cell Lymphoma (HSTCL) [Phase 4]
A Phase 4 study sponsored by Janssen banked samples from Crohn's disease and ulcerative colitis patients to identify biomarkers that may pre…
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CLINICAL_TRIALS trial_result · 2021-03-02Clinical Trial Update: Observational, Real World Study Of Inflectra In Patients With Inflammatory Bowel Disease
Observational real-world study of Inflectra in inflammatory bowel disease completed with results posted.
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FDA approval · 2021-02-24FDA Approved: ADALIMUMAB — Supplemental Application (Sandoz Inc)
FDA approval of a supplemental application for the adalimumab biosimilar ADALIMUMAB-ADAZ from Sandoz Inc.
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CLINICAL_TRIALS trial_result · 2021-02-24Clinical Trial Update: Open Label Efficacy and Safety of Anti-MAP (Mycobacterium Avium Ssp. Paratuberculosis) Therapy in Adult Crohn's Disease [Phase 3]
Phase 3 open-label trial assessing efficacy and safety of Anti-MAP therapy in adults with Crohn's disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-02-18Clinical Trial Update: Study to Evaluate Efficacy and Safety of Two Drug Regimens in Subjects With Moderate to Severe Crohn's Disease [Phase 3]
Phase 3 trial evaluating two regimens for moderate to severe Crohn's disease has completed and results were posted.
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CLINICAL_TRIALS trial_result · 2021-02-17Clinical Trial Update: Intraoperative TAP Block With Bupivacaine/Dexamethasone Against Liposomal Bupivacaine (Exparel®) [Phase 4]
Phase 4 trial comparing intraoperative TAP block with bupivacaine/dexamethasone to liposomal bupivacaine (Exparel) for postoperative pain; s…
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CLINICAL_TRIALS trial_result · 2021-02-15Clinical Trial Update: A Dose-finding Study of OPC-6535 in Patients With Active Crohn's Disease [Phase 2]
Phase 2 dose-finding trial for OPC-6535 in active Crohn's disease was terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-02-08Clinical Trial Update: Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease [Phase 2]
Phase 2 trial updating on gut microbiota modification for refractory Crohn's disease; results posted after completion.
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CLINICAL_TRIALS trial_result · 2021-02-04Clinical Trial Update: Fecal Microbiota Transplantation in Pediatric Patients [Phase 1]
Phase 1 clinical trial evaluating fecal microbiota transplantation in pediatric patients with inflammatory bowel diseases, completed with re…
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FDA approval · 2021-01-29FDA Approved: MERCAPTOPURINE — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA approved a supplemental application for mercaptopurine by Mylan Pharmaceuticals, updating the regulatory status for the marketed product…
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FDA approval · 2021-01-25FDA Approved: MERCAPTOPURINE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approves a supplemental application for mercaptopurine submitted by Hikma Pharmaceuticals USA Inc., indicating changes to the product's …
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FDA approval · 2021-01-15FDA Approved: AZULFIDINE EN-TABS — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
FDA approved a supplemental application for AZULFIDINE EN-TABS (sulfasalazine) from Pfizer, resulting in updated labeling and/or approved in…
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CLINICAL_TRIALS trial_result · 2021-01-15Clinical Trial Update: Anastomotic Leakage and Value Of Indocyanine Green in Decreasing Leakage Rates [Phase 3]
Phase 3 trial investigating the use of indocyanine green to reduce anastomotic leakage in colorectal surgery for colorectal cancer and Crohn…
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: Loss of Response of Adalimumab Biosimilar vs Adalimumab Original, in Inflammatory Bowel Disease. [Phase 4]
Phase 4 trial comparing loss of response between an adalimumab biosimilar and the original adalimumab in Crohn's disease and ulcerative coli…
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FDA approval · 2021-01-07FDA Approved: AZATHIOPRINE SODIUM — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approves a supplemental application for azathioprine sodium from Hikma Pharmaceuticals USA Inc., updating the generic product's approval…
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CLINICAL_TRIALS trial_result · 2020-12-22Clinical Trial Update: ASTIC Autologous Stem Cell Transplantation for Crohn's Disease [Phase 3]
Phase 3 trial of ASTIC autologous stem cell transplantation for Crohn's disease was terminated.
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CLINICAL_TRIALS trial_result · 2020-12-21Clinical Trial Update: Vedolizumab IV in Pediatric Participants With Ulcerative Colitis (UC) or Crohn's Disease (CD) [Phase 2]
Phase 2 trial of Vedolizumab IV in pediatric patients with Ulcerative Colitis or Crohn's Disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-12-14Clinical Trial Update: Diagnostic Validity of [18F]FSPG PET for the Assessment of Disease Activity in Inflammatory Bowel Disease [Phase 2]
Phase 2 trial assessing the diagnostic validity of 18F-FSPG PET for disease activity in inflammatory bowel diseases including ulcerative col…
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FDA approval · 2020-12-11FDA Approved: USTEKINUMAB — Supplemental Application (Janssen Biotech, Inc.)
FDA approved a supplemental application for ustekinumab filed by Janssen Biotech, Inc. The action updates the product's labeling.
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CLINICAL_TRIALS trial_result · 2020-12-10Clinical Trial Update: Usefulness of Contrast-enhanced Ultrasound (CEUS) in Crohn's Disease Pediatric Patients [Phase 4]
Phase 4 trial exploring the usefulness of contrast-enhanced ultrasound in pediatric Crohn's disease patients.
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FDA approval · 2020-12-01FDA Approved: USTEKINUMAB — Supplemental Application (Janssen Biotech, Inc.)
FDA approves a supplemental application for ustekinumab (Stelara) from Janssen Biotech, Inc., reflecting an approval of changes to its label…
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CLINICAL_TRIALS withdrawal · 2020-10-27Clinical Trial Update: Phase 4, Vedolizumab-4002 Post-marketing, Disease-Drug-Drug Interaction Study [Phase 4]
Phase 4 post-marketing study of Vedolizumab-4002 investigating drug–drug interactions has been withdrawn.
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CLINICAL_TRIALS trial_result · 2020-10-23Clinical Trial Update: Stricture Definition and Treatment (STRIDENT) Drug Therapy Study [Phase 4]
Phase 4 clinical trial update for STRIDENT drug therapy study addressing Crohn disease and inflammatory bowel diseases with intestinal stric…
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CLINICAL_TRIALS trial_result · 2020-10-08Clinical Trial Update: Efficacy and Safety Trial of RPC1063 for Moderate to Severe Crohn's Disease [Phase 2]
Phase 2 trial results for RPC1063 in moderate to severe Crohn's disease have been completed with results posted.