Crohn Disease
📧 Sign up to get email alerts when something new happens for Crohn Disease.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2021-10-25Clinical Trial Update: Imaging Biomarkers in Crohn's Associated Spondyloarthritis
Completed clinical trial evaluating imaging biomarkers in Crohn's disease-associated spondyloarthritis; results posted in 2021.
-
CLINICAL_TRIALS trial_result · 2021-10-21Clinical Trial Update: Triple Combination Therapy in High Risk Crohn's Disease (CD) [Phase 4]
Phase 4 clinical trial update for a triple combination therapy in high-risk Crohn's disease has completed with results posted.
-
FDA approval · 2021-10-15FDA Approved: ADALIMUMAB-ADBM — Supplemental Application (QUALLENT PHARMACEUTICALS HEALTH LLC)
FDA approves a supplemental application for the adalimumab biosimilar ADALIMUMAB-ADBM from Quallent Pharmaceuticals Health LLC. The approval…
-
CLINICAL_TRIALS trial_result · 2021-10-07Clinical Trial Update: Phase 3 Study of Cx601 in Participants With Complex Perianal Fistulising Crohn's Disease [Phase 3]
Phase 3 study of Cx601 (darvadstrocel) for complex perianal fistulas in adults with Crohn's disease has completed and posted results.
-
CLINICAL_TRIALS trial_result · 2021-09-28Clinical Trial Update: Pediatric Crohn's Disease AdalImumab Level-based Optimization Treatment (PAILOT) Trial [Phase 4]
Phase 4 pediatric trial assessing adalimumab level-based optimization (PAILOT) for Crohn's disease has completed.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2021-09-16Clinical Trial Update: Phase 2a Study of PRV-6527 in Subjects With Moderately to Severely Active Crohn's Disease [Phase 2]
Phase 2a study of PRV-6527 in moderately to severely active Crohn's disease has completed.
-
FDA approval · 2021-08-17FDA Approved: ENTYVIO — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA approved a supplemental application for ENTYVIO (vedolizumab) submitted by Takeda Pharmaceuticals America, Inc.
-
CLINICAL_TRIALS trial_result · 2021-08-05Clinical Trial Update: Ultra-proactive Therapeutic Drug Monitoring in Inflammatory Bowel Disease [Phase 4]
Phase 4 trial update on proactive therapeutic drug monitoring in inflammatory bowel disease has completed.
-
CLINICAL_TRIALS trial_result · 2021-07-21Clinical Trial Update: Trial of Specific Carbohydrate and Mediterranean Diets to Induce Remission of Crohn's Disease [NA]
A completed clinical trial evaluating specific carbohydrate and Mediterranean diets for inducing remission in Crohn's disease, with results …
-
CLINICAL_TRIALS trial_result · 2021-07-20Clinical Trial Update: Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases [Phase 2]
Phase 2 clinical trial evaluating low-dose IL-2 to induce regulatory T cells in various autoimmune and inflammatory diseases; trial complete…
-
CLINICAL_TRIALS trial_result · 2021-07-12Clinical Trial Update: An Open Label Safety and Tolerability Study of AIN457 in Patients With Moderate to Severe Crohn's Disease [Phase 2]
Phase 2 open-label safety and tolerability study of AIN457 in moderate to severe Crohn's disease was terminated; results were posted in 2021…
-
CLINICAL_TRIALS withdrawal · 2021-06-23Clinical Trial Update: A Study to Test Efficacy, Safety, and Pharmacokinetics of Certolizumab Pegol in Children and Adolescents With Moderately to Severely Active Crohn's Disease [Phase 3]
Phase 3 trial investigating Certolizumab Pegol in children and adolescents with Crohn's disease was withdrawn.
-
FDA approval · 2021-06-17FDA Approved: INFLECTRA — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
FDA approves a supplemental application for INFLECTRA (infliximab-dyyb) from Pfizer Laboratories Div Pfizer Inc, marking FDA action on a bio…
-
CLINICAL_TRIALS trial_result · 2021-06-15Clinical Trial Update: Efficacy and Safety of Oral OPS-2071 in Participants With Crohn's Disease Showing Symptoms of Active Inflammation [Phase 2]
Phase 2 trial assessing the efficacy and safety of oral OPS-2071 in Crohn's disease with active inflammation; study terminated with results …
-
CLINICAL_TRIALS trial_result · 2021-06-09Clinical Trial Update: Efficacy and Safety of Vedolizumab in Biologic-naïve Korean Patients With Moderate to Severe Inflammatory Bowel Disease [Phase 3]
Phase 3 trial evaluating vedolizumab in biologic-naïve Korean patients with moderate to severe inflammatory bowel disease (Crohn's disease a…
-
CLINICAL_TRIALS trial_result · 2021-06-09Clinical Trial Update: Dietary Treatment of Crohn's Disease [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating dietary treatment for Crohn's disease has completed.
-
CLINICAL_TRIALS trial_result · 2021-06-08Clinical Trial Update: A Trial of Yoga in Pediatric Inflammatory Bowel Disease [NA]
A completed clinical trial investigated yoga as an intervention for pediatric inflammatory bowel disease; results have been posted.
-
CLINICAL_TRIALS trial_result · 2021-05-25Clinical Trial Update: Safety and Efficacy of ALX-0600 in Subjects With Active Crohn's Disease [Phase 2]
A Phase 2 clinical trial evaluating ALX-0600 for safety and efficacy in active Crohn's disease has completed.
-
CLINICAL_TRIALS trial_result · 2021-05-19Clinical Trial Update: Study of Treat to Target Versus Routine Care Maintenance Strategies in Crohn's Disease Patients Treated With Ustekinumab [Phase 3]
A Phase 3 trial comparing treat-to-target maintenance strategies versus routine care in Crohn's disease patients treated with ustekinumab ha…
-
CLINICAL_TRIALS trial_result · 2021-05-18Clinical Trial Update: 5-HTP in Patients With IBD in Clinical and Biologic Remission:Effect on Fatigue Scores [Phase 2]
Phase 2 trial evaluating 5-HTP in patients with inflammatory bowel disease in clinical and biologic remission to assess effects on fatigue s…
-
CLINICAL_TRIALS trial_result · 2021-05-14Clinical Trial Update: Safety and Efficacy of ALX-0600 in Subjects With Active Crohn's Disease Who Completed Protocol CL0600-008 [Phase 2]
Phase 2 trial update on ALX-0600 for Crohn's disease completed; safety and efficacy data reported.
-
CLINICAL_TRIALS trial_result · 2021-05-11Clinical Trial Update: Efficacy and Safety Study of Ontamalimab as Induction Therapy in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 306) [Phase 3]
Phase 3 trial for ontamalimab as induction therapy in moderate to severe Crohn's disease; study terminated with posted results.
-
CLINICAL_TRIALS trial_result · 2021-04-29Clinical Trial Update: Efficacy and Safety Study of Ontamalimab as Induction Therapy in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 305) [Phase 3]
Phase 3 trial of ontamalimab as induction therapy for moderate-to-severe Crohn's disease terminated; results posted in 2021.
-
CLINICAL_TRIALS trial_result · 2021-04-28Clinical Trial Update: A Clinical Trial of Antibody GSK1070806 in the Treatment of Patients With Moderate to Severe Crohn's Disease [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the antibody GSK1070806 for moderate to severe Crohn's disease has completed.
-
CLINICAL_TRIALS research · 2021-04-21Clinical Trial Update: Perianal Fistula (PAF) Validation and Burden of Illness Study
A completed clinical trial update studying perianal fistula in inflammatory bowel disease, focusing on validation and burden of illness.