Crohn Disease
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CLINICAL_TRIALS research · 2024-11-29Clinical Trial Update: Standardized Fecal Microbiota Transplantation for Crohn&Apos;s Diseases [NA]
This clinical trial update reports a recruiting study evaluating standardized fecal microbiota transplantation for Crohn's disease.
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Evolution and Treatments of Chronic Inflammatory Systemic Diseases
A recruiting study (NCT04191395) exploring evolution and treatment of chronic inflammatory systemic diseases, including inflammatory bowel d…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Wild Blueberries in Colitis [NA]
Clinical trial update noting ongoing recruitment for a study of wild blueberries in ulcerative colitis and Crohn's disease.
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: High Dose Steroid Therapy to Treat Flares in Patients With Inflammatory Bowel Disease (IBD) [Phase 1]
Phase 1 trial evaluating high-dose systemic corticosteroid therapy to treat flares in inflammatory bowel disease has completed.
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Investigating the Anti-inflammatory Effects of Frondanol in Adults With Inflammatory Bowel Disease [Phase 2, Phase 3]
The study update indicates completion of Phase 2 and Phase 3 trials evaluating Frondanol for anti-inflammatory effects in adults with inflam…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: WAter Preparation in Crohn's Disease's Imagery [NA]
Clinical trial update indicates a NOT_YET_RECRUITING study sponsored by University Hospital, Toulouse addressing Crohn's disease. The trial …
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CLINICAL_TRIALS research · 2024-11-13Clinical Trial Update: The Utility of Hand-held Ultrasound Devices to Detect Bowel Wall Inflammatory Activity in Crohn's Disease
This clinical trial evaluates the utility of hand-held ultrasound devices to detect bowel wall inflammatory activity in Crohn disease, with …
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CLINICAL_TRIALS withdrawal · 2024-11-12Clinical Trial Update: 90Second IBD for the Improvement of Self Efficacy and Quality of Life in Inflammatory Bowel Disease Patients [NA]
The clinical trial investigating 90Second IBD for improving self-efficacy and quality of life in Crohn's disease and ulcerative colitis has …
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: A Study of Moderate to Severe Inflammatory Bowel Disease, Including Ulcerative Colitis (UC) and Crohn's Disease (CD)
Takeda-sponsored trial evaluating a treatment for moderate-to-severe inflammatory bowel disease, including ulcerative colitis and Crohn's di…
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: A Study to Test Long-term Treatment With Spesolimab in Patients With Fistulising Crohn's Disease Who Took Part in Previous Trials [Phase 2]
The Phase 2 study evaluating long-term Spesolimab in patients with fistulising Crohn's disease has been terminated, and trial results have b…
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Induction Optimization With Stelara for Crohn's Disease [Phase 4]
A Phase 4 trial evaluating induction optimization with ustekinumab (Stelara) for Crohn's disease was terminated, with results posted.
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CLINICAL_TRIALS research · 2024-11-04Clinical Trial Update: Fecal Microbiota Transplantation in Pediatric Crohn's Disease [NA]
A pediatric Crohn's disease trial evaluating fecal microbiota transplantation is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: Entyvio (Vedolizumab) Long Term Safety Study
This document reports the completion of a long-term safety study of Vedolizumab (Entyvio) in ulcerative colitis and Crohn's disease.
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Study To Evaluate The Efficacy And Safety Of Oral PF-06651600 And PF-06700841 In Subjects With Moderate To Severe Crohn's Disease [Phase 2]
Pfizer completed a Phase 2 study evaluating the efficacy and safety of oral PF-06651600 and PF-06700841 in moderate-to-severe Crohn's diseas…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Evaluation of the Effectiveness of Kits Promonitor-IFX/ADL and Promonitor-Anti-IFX/ADL in Patients With IBD
This clinical trial update reports on the effectiveness of Promonitor-IFX/ADL and Promonitor-Anti-IFX/ADL kits in patients with inflammatory…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: A Study of Guselkumab for the Treatment of Participants With Crohn's Disease After Surgical Resection [Phase 3]
Phase 3 trial evaluating guselkumab for Crohn's disease after surgical resection was terminated, with results posted.
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CLINICAL_TRIALS research · 2024-10-23Clinical Trial Update: LMT503 First-in-human SAD, MAD, and FE Study [Phase 1]
Lmito Therapeutics reports a first-in-human Phase 1 study of LMT503 evaluating SAD, MAD, and single-dose escalation; the trial is not yet re…
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CLINICAL_TRIALS research · 2024-10-23Clinical Trial Update: Calculating the LEmann IndeX Using InTEstiNal Ultrasound
This clinical trial update describes calculating the LeMan Index using intestinal ultrasound for Crohn's disease and notes that the study is…
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: A Phase 2 Clinical Trial: Xanthohumol Metabolism and Signature (XMaS) in Crohn's Disease [Phase 2]
A Phase 2 trial named XMaS is evaluating xanthohumol metabolism and signature in Crohn's disease. The trial is currently active but not recr…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in Real-World Practice
This update reports the completion of a real-world study evaluating vedolizumab in adults with ulcerative colitis or Crohn's disease.
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FDA approval · 2024-10-10FDA Approved: IMULDOSA — Original Application (Accord BioPharma Inc.)
The FDA approves Imuldosa (ustekinumab-srlf) from Accord BioPharma Inc. under an Original Biologics License Application, expanding treatment…
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: EXL01 in the Maintenance of Steroid-induced Clinical Response/Remission in Participants With Mild to Moderate Crohn's Disease [Phase 1]
A Phase 1 clinical trial evaluating EXL01 for maintenance of steroid-induced response/remission in mild to moderate Crohn's disease has been…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: OTIS Vedolizumab Pregnancy Exposure Registry
This clinical trial registry update reports that the OTIS Vedolizumab Pregnancy Exposure Registry (NCT02678052) has completed data collectio…
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CLINICAL_TRIALS research · 2024-10-08Clinical Trial Update: TRansmural hEaliNg Definition in CroHn's Disease (TRENCH 1)
A clinical trial update indicating that the TRansmural Healing Definition in Crohn's Disease (TRENCH 1) is currently recruiting, sponsored b…
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CLINICAL_TRIALS research · 2024-10-08Clinical Trial Update: Validation of Scoring Systems for Differentiating Intestinal Tuberculosis from Crohn's Disease
A study validating scoring systems to differentiate intestinal tuberculosis from Crohn's disease is currently recruiting.