Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Analysis of Intestinal Defensin Expression in Acute GVHD
A completed University of Freiburg trial analyzes intestinal defensin expression in acute graft-versus-host disease. The study also relates …
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Individual Treatment of Ustekinumab in Perianal Fistulizing Crohn's Disease
This clinical trial update describes a study evaluating ustekinumab for perianal fistulizing Crohn's disease that is not yet recruiting.
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FDA approval · 2024-12-17FDA Approved: STEQEYMA — Original Application (CELLTRION USA, Inc.)
FDA approved STEQEYMA (ustekinumab-stba) from Celltrion USA as a biosimilar to ustekinumab under an original biologics license application. …
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Health-related Physical Fitness in Patients with Inflammatory Bowel Disease
A completed clinical trial evaluating health-related physical fitness in patients with inflammatory bowel disease, including ulcerative coli…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Development and Validation of a New Paediatric Inflammatory Bowel Disease NUTrition Risk Score (PIBD-NUTS)
Development and validation of a new pediatric nutrition risk score for inflammatory bowel disease (PIBD-NUTS) is being studied, with ongoing…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Effects of Vaping on Post-operative Recurrence of Crohn's Disease
This clinical trial is investigating whether vaping affects endoscopic recurrence of Crohn's disease after surgical resection and is current…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Impact of Diet and Lifestyle Modification on the Intestinal Barrier Integrity in Crohn's Disease [NA]
A clinical trial assesses the effect of diet and lifestyle modification on intestinal barrier integrity in Crohn's disease and is currently …
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EMA withdrawal · 2024-12-13Alofisel withdrawn from the EU market
The EMA has withdrawn Alofisel from the EU market. It determined that the medicine's benefit in Crohn's disease is no longer demonstrated.
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: Urine Metabolites in the Diagnosis of Disease
Luventix, Inc. is sponsoring a clinical trial that investigates urine metabolites for disease diagnosis and is currently recruiting, targeti…
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: Autophagy in Paediatric Crohn's Disease [NA]
This clinical trial, sponsored by Hospices Civils de Lyon, investigates autophagy in pediatric Crohn's disease and is not yet recruiting.
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: MSC Intratissular Injection in Crohn Disease Patients [Phase 1, Phase 2]
A Phase 1/2 clinical trial from the University of Liege is evaluating an intratissular injection of mesenchymal stem cells for Crohn's disea…
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Remote Monitoring of Patients With an Inflammatory Bowel Disease Under no or Maintenance Therapy [NA]
Clinical trial update describing a study on remote monitoring for inflammatory bowel disease patients who are not on active therapy or are o…
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: The CROCO Study: CROhn's Disease COhort Study [NA]
This document provides an update on the CROCO Study, a Crohn's disease cohort trial sponsored by GLSMED Learning Health S.A., currently recr…
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Prevention of Postoperative Endoscopic Recurrence with Endoscopy-driven Versus Systematic Biological Therapy [Phase 4]
Phase 4 clinical trial comparing an endoscopy-driven strategy with systematic biological therapy to prevent postoperative endoscopic recurre…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: InDuctIon TREatment with SubCuTaneous Infliximab for Crohn's Disease [Phase 3]
A Phase 3 trial is evaluating subcutaneous infliximab for Crohn's disease and is currently recruiting at Academic Medical Center - Universit…
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: Inflammatory Bowel Disease(IBD), Treatment Response
The clinical trial evaluating treatment response in inflammatory bowel diseases, including ulcerative colitis and Crohn's disease, sponsored…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Use of FDG PET/CT to Evaluate Crohn Disease [Phase 2]
A Phase 2 clinical trial evaluating FDG PET/CT imaging as a tool to assess Crohn's disease activity.
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Assessment of Non-invasive Tools for Detecting Active Inflammatory Bowel Disease
This clinical trial update describes a study evaluating non-invasive tools for detecting active inflammatory bowel disease. The conditions i…
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Markers of Oxidative Stress in Inflammatory Bowel Diseases: Risk Factors and Implications for a Dietetic Approach [NA]
This clinical trial update describes research on oxidative stress markers in inflammatory bowel diseases and explores risk factors and impli…
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Evaluation of the Efficacy of Local Budesonide Treatment in Children with Crohn's Disease Located in the Esophagus And/or Stomach And/or Duodenum [Phase 2, Phase 3]
A pediatric clinical trial evaluating local budesonide for Crohn's disease located in the esophagus, stomach, and/or duodenum, currently in …
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Induction Study #2 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease [Phase 3]
A Phase 3 induction study evaluating oral ozanimod for moderately to severely active Crohn's disease has completed and posted results.
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic
A Czech Republic clinical study on the epidemiology, management, and comorbidity patterns of alopecia areata has completed.
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: Risankizumab in Children With Crohn's Disease (RisaKids) [NA]
A pediatric trial called RisaKids is evaluating risankizumab (Skyrizi) for Crohn's disease and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-02Clinical Trial Update: Open-Label Extension and Safety Study for Participants With Crohn's Disease Previously Enrolled in the Etrolizumab Phase III Study GA29144 [Phase 3]
Open-label extension and safety study of etrolizumab in Crohn's disease patients previously enrolled in the GA29144 phase III trial has term…
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FDA approval · 2024-11-29FDA Approved: YESINTEK — Original Application (Biocon Biologics Inc.)
FDA approved Yesintek (ustekinumab) from Biocon Biologics Inc. under an Original Application. It covers the established ustekinumab indicati…