Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: The Risk of Venous Thromboembolism in Systemic Inflammatory Disorders: a United Kingdom (UK) Matched Cohort Study
Results from a UK matched-cohort study examine the risk of venous thromboembolism among people with systemic inflammatory disorders. The tri…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease [Phase 2]
A Phase 2 clinical trial is investigating therapeutic targets beyond inflammation for Crohn's disease and is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: PATHFINDER: Evaluating the Optimal First-Line Treatment Strategy for Moderate-to-Severely Active Ileal-dominant Crohn's Disease [Phase 4]
Clinical Trial Update: PATHFINDER is a Phase 4 study evaluating optimal first-line treatment strategies for moderate-to-severely active ilea…
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CLINICAL_TRIALS withdrawal · 2025-06-11Clinical Trial Update: CUP Certolizumab Pegol (CDP-870) in Adults Suffering From Crohn's Disease (CD)
The clinical trial of certolizumab pegol (CDP-870) in adults with Crohn's disease is no longer available.
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: A Double-Blind, Randomized, Placebo-Controlled Phase II Clinical Trial to Evaluate the Safety and Efficacy of L2-01 in Subjects With Crohn's Disease [Phase 2]
Phase II trial protocol evaluating safety and efficacy of L2-01 versus placebo in Crohn's disease; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: Evaluation of Ability to Detect Bowel Gas During Laparoscopic Right Colectomy With Intracorporeal Anastomosis [NA]
This clinical trial update reports on the ability to detect bowel gas during laparoscopic right colectomy with intracorporeal anastomosis; t…
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Prevention of Recurrent Clostridium Difficile Infection (CDI) in Patients With Inflammatory Bowel Disease (IBD). [Phase 4]
Phase 4 trial evaluating prevention of recurrent Clostridioides difficile infection in patients with inflammatory bowel disease. The study w…
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CLINICAL_TRIALS withdrawal · 2025-06-05Clinical Trial Update: A Pilot Study to Explore the Role of Gut Flora in Crohn's Disease
A pilot clinical trial studying the role of gut flora in Crohn's disease sponsored by ProgenaBiome has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: A Study to Learn About the Study Medicine Called Infliximab (Genetical Recombination)[Infliximab Biosimilar 3] in People With Rheumatoid Arthritis, Ulcerative Colitis, Crohn's Disease, or Psoriasis
Pfizer-sponsored trial of infliximab biosimilar 3 in rheumatoid arthritis, ulcerative colitis, Crohn's disease, and psoriasis has completed …
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease [Phase 3]
This is a Phase 3 clinical trial evaluating vedolizumab with and without upadacitinib in adults with Crohn's disease; the study is currently…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Spondylo-arthritis Screening Tool Among Patient Suffering From Inflammatory Bowel Disease
This clinical trial update describes the development of a screening tool to identify spondyloarthritis in patients with inflammatory bowel d…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Dietary Modification In Inflammatory Bowel Disease Patients [NA]
A dietary modification study in Crohn's disease patients is currently recruiting. The protocol focuses on diet rather than pharmacologic the…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: ROLL'YN-UST: an Observational Study in Patients Treated by Steqeyma®, an Ustekinumab Biosimilar
An observational study evaluating Steqeyma, a biosimilar of ustekinumab, in patients with Crohn's disease and plaque psoriasis; recruitment …
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CLINICAL_TRIALS trial_result · 2025-05-30Clinical Trial Update: The Effects of Bifidobacterium Breve Bif195 for Small Intestinal Crohn's Disease [NA]
A completed clinical trial evaluating the effects of the probiotic Bif195 (Bifidobacterium breve Bif195) for small intestinal Crohn's diseas…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Threonine Requirement in Adult Males With Crohn's Disease Using IAAO [NA]
A clinical trial is recruiting adult males with Crohn's disease to study threonine requirements using IAAO, sponsored by The Hospital for Si…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Efficacy and Safety of Discontinuing 5-ASA in Patients With Inflammatory Bowel Disease [NA]
This clinical trial update assesses the efficacy and safety of discontinuing 5-ASA therapy in patients with inflammatory bowel disease, incl…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Investigation of the Correlation Between Polyamine Levels and Their Key Enzymatic Activities in Association With Inflammatory Bowel Disease Progression
A clinical trial investigating whether polyamine levels and the activity of their key enzymes correlate with the progression of inflammatory…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: NAZA - Nottingham/Astra ZenecA Prospective IBD Cohort Study
This clinical trial update shows a prospective inflammatory bowel disease (IBD) cohort study conducted in Nottingham is currently recruiting…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Cellvizio to Evaluate Margins in Crohn's Ileal Disease [NA]
A clinical trial update indicates that Cellvizio will be used to evaluate margins in Crohn's ileal disease, with recruitment ongoing. The st…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease: an Open-label Randomized Controlled Trial [Phase 3]
An open-label Phase 3 trial is evaluating azathioprine versus methotrexate as part of combination therapy with adalimumab in Crohn's disease…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: TDM Guided Early Optimization of ADAL in Crohn's Disease [NA]
Clinical trial NCT03261102 is evaluating therapeutic drug monitoring-guided early optimization of adalimumab in Crohn's disease. The study i…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Phase 1b/2a Trial of Allogeneic HSCT From an HLA-partially Matched Related or Unrelated Donor After TCRab+ T-cell/CD19+ B-cell Depletion for Patients With Monogenic and/or Early-onset Medically Refractory Crohn Disease [Phase 1, Phase 2]
Phase 1/2 trial evaluating allogeneic hematopoietic stem cell transplantation with TCRab+ T-cell and CD19+ B-cell depletion for monogenic or…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Small Bowel Deep Learning Algorithm Project [NA]
Clinical trial update for a small bowel deep learning algorithm project focused on Crohn disease, sponsored by London North West Healthcare …
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FDA approval · 2025-05-22FDA Approved: STARJEMZA — Original Application (Hikma Pharmaceuticals USA Inc.)
FDA approved STARJEMZA (ustekinumab-hmny) from Hikma Pharmaceuticals USA Inc. as a biosimilar to ustekinumab, enabling marketing for the sam…
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Post-marketing Registry Study of Infliximab for Injection in Chinese Pediatric Crohn's Disease Patients [Phase 4]
A Phase 4 post-marketing registry study evaluating infliximab injections in Chinese pediatric Crohn's disease patients is currently recruiti…