Crohn Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2025-07-08Clinical Trial Update: A Study to Check How Often People Treated With Darvadstrocel for Crohn's Disease Are Diagnosed With Cancer
A clinical trial evaluating cancer incidence in people treated with darvadstrocel for Crohn's disease with complex perianal fistula has been…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: VTX958 for the Treatment of Moderately to Severely Active Crohn's Disease [Phase 2]
A Phase 2 trial evaluating VTX958 for moderately to severely active Crohn's disease has been terminated.
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FDA approval · 2025-07-01FDA Approved: MESALAMINE — Supplemental Application (Alembic Pharmaceuticals Limited)
FDA approves a supplemental application for Mesalamine from Alembic Pharmaceuticals Limited.
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Randomized Controlled Trial Comparing Remote Patient Monitoring vs Standard Care in IBD Patients Initiating or Changing Advanced Therapy [Phase 3]
A Phase 3 randomized trial is evaluating remote patient monitoring versus standard care for inflammatory bowel disease patients initiating o…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Personalized AZithromycin/metronidAZole Therapy in Pediatric Crohn's Disease (CD) [Phase 2]
A Phase 2 trial assessing personalized azithromycin and metronidazole therapy for pediatric Crohn's disease was terminated, with results pos…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: An Observational Study to Assess Participant-Reported Real-World Experience of Risankizumab On-body Injector (OBI) for the Treatment of Crohn's Disease in Adult Participants in the United Kingdom (UK)
An observational study assessing adult participants' real-world experiences using the Risankizumab On-body Injector for Crohn's disease in t…
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FDA label_change · 2025-06-27FDA Approved: USTEKINUMAB — Supplemental Application (Janssen Biotech, Inc.)
FDA approves a supplemental application for Ustekinumab (Stelara) by Janssen Biotech, resulting in updated labeling.
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FDA approval · 2025-06-26FDA Approved: MERCAPTOPURINE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved Hikma Pharmaceuticals USA Inc.'s supplemental application for mercaptopurine, enabling continued marketing of the generic p…
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Empagliflozin as a Treatment for Severe Congenital Neutropenia Due to G6PC3 Deficiency [Phase 1]
A Phase 1 clinical trial evaluating empagliflozin for severe congenital neutropenia due to G6PC3 deficiency has completed, per the NIAID-spo…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: A Retrospective Observational Study of Ustekinumab Among Bio-naive Participants With Crohn's Disease in China
A completed retrospective observational study evaluating ustekinumab use in biologic-naive Crohn's disease patients in China.
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Assessing Interventions of Diet in IBD [NA]
A McMaster University-led clinical trial is recruiting to evaluate the effects of dietary interventions on inflammatory bowel disease, inclu…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: A Study on the Associations of Toll-like Receptor 5 Gene Polymorphisms With Crohn's Disease in Chinese Patients
This completed clinical trial investigates associations between Toll-like receptor 5 gene polymorphisms and Crohn's disease in Chinese patie…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Enabling Microbiomics- Driven Personalized Nutrition
A Mayo Clinic-led clinical trial is exploring microbiome-driven personalized nutrition for inflammatory bowel disease and irritable bowel sy…
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EMA approval · 2025-06-24EMA Authorised: Zessly (infliximab) — Sandoz GmbH
EMA authorised Zessly (infliximab) from Sandoz GmbH as a biosimilar for treatment of several inflammatory diseases, including rheumatoid art…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: IUS Predicts Guselkumab Efficacy in Patients With Moderate to Severe Crohn's Disease：a Prospective Study
A prospective study is evaluating whether intestinal ultrasound can predict guselkumab efficacy in moderate-to-severe Crohn's disease. The t…
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FDA approval · 2025-06-17FDA Approved: MESALAMINE — Supplemental Application (Actavis Pharma, Inc.)
FDA approved a supplemental application for MESALAMINE from Actavis Pharma, Inc., resulting in approval of a supplemental to the approved ge…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Comparing Endoscopic Strictureplasty vs. Balloon Dilation in Crohn's Disease Strictures [NA]
A clinical trial comparing endoscopic strictureplasty versus balloon dilation for Crohn's disease-related strictures is currently recruiting…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Safety and Efficacy of EcoActive on Intestinal Adherent Invasive E. Coli in Patients With Inactive Crohn's Disease [Phase 1, Phase 2]
This clinical trial update reports ongoing Phase 1/2 evaluation of EcoActive for safety and efficacy in patients with inactive Crohn's disea…
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FDA approval · 2025-06-13FDA Approved: AZATHIOPRINE — Supplemental Application (Ascend Laboratories, LLC)
The FDA approved a supplemental application for azathioprine from Ascend Laboratories, LLC.
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Spiritual Needs of European Patients With Inflammatory Bowel Disease and Their Caregivers
This clinical trial update describes a study funded by the University of Padova examining the spiritual needs of European patients with infl…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease
This clinical trial update reports on biomarkers of intestinal fibrosis in small bowel Crohn's disease. The study is currently active but no…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Serum Bovine Immunoglobulin (SBI) in Children and Young Adults With Inflammatory Bowel Disease (IBD) [EARLY_Phase 1]
The early-phase trial of Serum Bovine Immunoglobulin (SBI) in children and young adults with inflammatory bowel disease has been terminated.
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Contrast Enhanced Ultrasound in Human Crohn's Disease-Lumason
This is a clinical trial update about using Lumason-enhanced ultrasound to study Crohn's disease, sponsored by Cincinnati Children's Hospita…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy [Phase 1, Phase 2]
Pilot and feasibility phase 1/2 trial investigating 2'-fucosyllactose as a dietary supplement in inflammatory bowel disease patients on stab…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Reverse-Engineering of Exclusive Enteral Nutrition (RE-EEN) in Crohn's Disease: A Multi-Center Trial [NA]
A multi-center clinical trial evaluating reverse-engineering of exclusive enteral nutrition (RE-EEN) in Crohn's disease is currently recruit…