Critical Illness
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Enhanced Protein Intake to Support Muscle Protein Synthesis in ICU [NA]
A Maastricht University Medical Center trial is investigating whether enhanced protein intake supports muscle protein synthesis in criticall…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Psychological Impact of COVID-19 Outbreak on Caregivers
The clinical trial investigating the psychological impact of the COVID-19 outbreak on caregivers has completed.
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Measuring Total Energy Expenditure in Critically Ill Patients Using the Doubly Labelled Water Method [NA]
This clinical trial update describes a study to measure total energy expenditure in critically ill patients using the doubly labeled water m…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: NIBP Validation Study
An update on an ongoing NIBP validation study sponsored by Philips, currently recruiting for critical illness patients.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Optimizing Enteral Nutrition Regimen for Critically Ill Patients [NA]
This clinical trial update describes a study on optimizing enteral nutrition regimens for critically ill patients that is not yet recruiting…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Night-time Dexmedetomidine-esketamine Infusion and Sleep Quality in ICU Patients [Phase 4]
Phase 4 clinical trial evaluating a night-time infusion of dexmedetomidine and esketamine to improve sleep quality in ICU patients on mechan…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Remimazolam vs Midazolam to Reduce Delirium in Adults ≥65 Undergoing CPB Valve Surgery [Phase 4]
A Phase 4 clinical trial compares remimazolam with midazolam to reduce delirium in adults aged 65 and older undergoing cardiopulmonary bypas…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Effect of Combined IV Bolus Amino Acid Supplementation and Mobilisation on Skeletal Muscle During the First 10 Days in the ICU: A RCT [NA]
This completed randomized controlled trial evaluated whether combining intravenous amino acid bolus supplementation with mobilisation improv…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Practice of Fluid Therapy in Critically Ill Invasively Ventilated Patients
The clinical trial NCT05968066 evaluating fluid therapy and vasopressor use in critically ill, invasively ventilated patients has completed.
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Identifying Diabetes and Impaired Glucose Tolerance in ICU Patients
A recruiting clinical trial aims to identify diabetes and impaired glucose tolerance among ICU patients.
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: ICU Combined Assessment of Cardio-Respiratory Exercise
Clinical trial update for ICU Combined Assessment of Cardio-Respiratory Exercise. The study is currently recruiting and focuses on ICU-acqui…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: The Blood-Interstitial Glucose Gap
This clinical trial update reports the completion of a study on the blood-interstitial glucose gap sponsored by the Chinese Medical Associat…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Surface Electrical Myography, Oxygen Consumption, Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Unit
A clinical trial at Leiden University Medical Center is evaluating surface electrical myography, oxygen consumption, effort, and weaning out…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Physiotherapy and Optimised Nutrition in Survivors of Critical Illness [NA]
A completed clinical trial evaluating physiotherapy and optimized nutrition in survivors of critical illness.
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: The VITDALIZE Study: Effect of High-dose Vitamin D3 on 28-day Mortality in Adult Critically Ill Patients [Phase 3]
A Phase 3 trial is evaluating whether high-dose vitamin D3 can reduce 28-day mortality in adults who are critically ill and vitamin D defici…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Time Limited Trials to Reduce Non-Beneficial Intensive Care Unit Treatments [NA]
This completed clinical trial from the Lundquist Institute studied time-limited trials to reduce non-beneficial ICU treatments in critically…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: General Surgery Patients at the Intensive Care Unit
Clinical trial update indicates a study on general surgery patients in the intensive care unit is not yet recruiting, sponsored by Hospital …
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Blood-Interstitial Fluid Glucose Gap
A completed clinical trial from the Chinese Medical Association evaluated the gap between blood glucose and interstitial fluid glucose in cr…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Capillary Refill Time Calculated With a Video-assisted Method Has a Better Reproducibility Than Visual Method in Critically Ill Patients [NA]
The study found that a video-assisted capillary refill time method has better reproducibility than the traditional visual method in critical…
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CLINICAL_TRIALS other · 2025-11-18Clinical Trial Update: Protein Delivery in Intermittent and Continuous Enteral Nutrition in ICU Patients [NA]
A clinical trial update noting a study on protein delivery during intermittent and continuous enteral nutrition in ICU patients with muscle …
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)
Duke University is conducting the OPTIC opportunistic PK/PD trial in critically ill children that is currently recruiting. The study involve…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Pivotal Evaluation of Abdominal Neuromuscular Electrical Stimulation (VentFree) for Weaning From Mechanical Ventilation [NA]
Clinical trial update evaluating abdominal neuromuscular electrical stimulation (VentFree) for facilitating weaning from mechanical ventilat…
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle [NA]
An ongoing randomized controlled trial at Yale is evaluating a sleep chronobundle to reestablish sleep and circadian alignment in critically…
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CLINICAL_TRIALS trial_result · 2025-10-28Clinical Trial Update: Assessing the Impact of LIve Music in the Intensive Care Unit (ICU) to Improve Care for Critically Ill Patients [NA]
A completed clinical trial evaluated the effect of live music therapy in the ICU on anxiety and pain among critically ill patients.
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: Safety and Feasibility of a Self-Balancing Exoskeleton for Rehabilitation in the Thoracic Surgical Intensive Care Unit: a Pilot Trial [Phase 1, Phase 2]
This Phase 1/2 pilot trial evaluates the safety and feasibility of a self-balancing exoskeleton for rehabilitation in the thoracic surgical …