Critical Illness
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: 12-hour Time Limited Feeding in Critical Care [NA]
This entry describes a study evaluating 12-hour time-limited feeding in critically ill patients, which is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Sedation Efficacy and Safety of Remazolam Besylate in Ventilated Surgical Critically Ill Patients [Phase 4]
Phase 4 clinical trial evaluating the sedation efficacy and safety of Remazolam Besylate in ventilated, critically ill surgical patients; cu…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Effectiveness of Familiar Voices and Nature Sounds Among Critically Ill Comatose Patients [NA]
A completed clinical trial evaluating whether familiar voices and nature sounds aid recovery or comfort in critically ill, comatose patients…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Assessment of Kidney Function and Osteomuscular Status After Critical Care
The trial update indicates that the study assessing kidney function and osteomuscular outcomes after critical care has been suspended.
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Protein Dosing Strategies in Critically Ill Patients: Comparing Actual Body Weight and Fat-Free Mass Approaches in an Observational Cohort Study
This observational cohort study explores protein dosing strategies in critically ill patients, comparing dosing based on actual body weight …
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: Real-Time Algorithm-Driven Ventilation Feedback to Improve Lung-Protective Ventilation in Critically Ill Patients [NA]
A clinical trial is evaluating real-time algorithm-driven ventilation feedback to promote lung-protective ventilation in critically ill pati…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Pathological Myeloid Activation After Sepsis and Trauma
A clinical trial sponsored by the University of Florida is investigating pathological myeloid activation after sepsis and trauma. The study …
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Role of End-Tidal CO2 During Passive Leg Raising to Predict Fluid Responsiveness in ICU
A clinical trial evaluating whether end-tidal CO2 changes during a passive leg-raising maneuver can predict fluid responsiveness in ICU pati…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Population Pharmacokinetics of Remifentanil in Low-Weight Critically Ill Patients
A population pharmacokinetics study of remifentanil in low-weight critically ill patients is currently recruiting to improve dosing guidance…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Prevalence of Sarcopenia in Patients Admitted to ICU and Its Progression During Hospitalization.
Clinical trial update indicates that the study examining the prevalence of sarcopenia in ICU patients and its progression during hospitaliza…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Intrahospital Transport in Patients With High-flow Nasal Oxygenation: Prospective Observational Study
A completed prospective observational study evaluating intrahospital transport safety for patients receiving high-flow nasal oxygen.
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Intraabdominal Hypertension and Occurrence of Microaspiration in Cirrhotics Under Mechanical Ventilation
Clinical trial investigating intraabdominal hypertension and microaspiration in cirrhotic patients on mechanical ventilation is currently re…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Impact of Mallinckrodt Electronic Device on Continuous Control of Tracheal Cuff Pressure [NA]
A completed clinical trial evaluated Mallinckrodt's electronic device for continuous control of tracheal cuff pressure in critically ill pat…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Impact of Tracheal Cuff Shape on Microaspiration in Intensive Care Units [NA]
A completed clinical trial examining how tracheal cuff shape affects microaspiration in ICU patients on mechanical ventilation.
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: PICU Up!: A Pilot Stepped-wedge Trial of a Multicomponent Early Mobility Intervention for Critically Ill Children [NA]
Status update for the PICU Up! trial—a pilot stepped-wedge study evaluating an early mobility intervention in critically ill children. The c…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: CONFOCAL-2 Interventional Pilot Study [Phase 1, Phase 2]
A Phase 1/2 interventional pilot study (CONFOCAL-2) completed, investigating a therapy for critical illness and respiratory failure.
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Adjuvant Continuous Infusion of Nefopam Versus Standard of Care in Mechanically Ventilated Critically Ill Patients: Randomized Double-blind Controlled Study [Phase 3]
A Phase 3 randomized, double-blind trial comparing adjuvant continuous infusion of nefopam to standard analgesia in mechanically ventilated …
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Pressure Support and Positive End Expiratory Pressure During Spontaneous Breathing Trial [NA]
Clinical trial update on pressure support and positive end-expiratory pressure during spontaneous breathing trials in critically ill adults …
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 randomized study evaluating point-of-care AI assistance to improve outcomes in critic…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Crystalloid Fluid Choice and Neurological Outcome in Patients After Subarachnoid Haemorrhage [NA]
An ongoing clinical trial is evaluating crystalloid fluid choice and neurological outcomes in patients after subarachnoid hemorrhage, and is…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Factor Associated With Mortality in the ICU
A clinical trial from Hospital Departamental de Villavicencio is examining factors associated with mortality in critically ill ICU patients …
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Azithromycin for Critical Asthma - Pediatrics [Phase 2, Phase 3]
A pediatric trial update indicates ongoing Phase 2 and Phase 3 studies evaluating azithromycin for pediatric asthma with critical illness; r…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Pilot Study on Device-assisted Mobilisation of Critically Ill Patients [NA]
Pilot study completion evaluating device-assisted mobilisation to address muscle weakness in critically ill patients, sponsored by Charité U…
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: Family-Participatory Early Rehabilitation in Critically Ill Patients [NA]
A clinical trial evaluating family-participatory early rehabilitation in critically ill patients has completed.
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Antimicrobial Treatment in Patients With Ventilator-associated Tracheobronchitis [Phase 4]
A Phase 4 trial evaluating antimicrobial therapy for ventilator-associated tracheobronchitis in mechanically ventilated, critically ill pati…